Assessment of Myocardial Perfusion with Contrast Enhanced Echocardiography

Routine two-dimensional echocardiography is an excellent, high resolution means of delineating anatomical structures and determining myocardial function. The more recent addition of Doppler ultrasound techniques allows assessment of the direction and velocity of intracardiac blood flow and has proven valuable for investigating cardiac valvular and shunt lesions. Until recently, cardiac ultrasound has offered no method of evaluating myocardial perfusion, other than the assessment of the end result of ischemia, that is detection of wall-motion abnormalities. During the past several years, the potential of contrast echocardiography to fill this void in cardiac ultrasound has been demonstrated. The purpose of this review is to review the background of this exciting new development and outline its current status with respect to the quantitation of myocardial blood flow and infarct size determination.

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