Activation of the CKI-CDK-Rb-E2F Pathway in Full Genome Hepatitis C Virus-expressing Cells*
暂无分享,去创建一个
Yutaka Hoshikawa | Kazunari Taira | Michael Reth | F. Shibasaki | M. Reth | M. Kohara | K. Taira | Y. Hoshikawa | K. Tsukiyama-Kohara | Michinori Kohara | Shigenobu Toné | Yohsuke Minatogawa | Kazuaki Inoue | Futoshi Shibasaki | Kazuaki Inoue | Hideko Nuriya | Kyoko Tsukiyama-Kohara | Isao Maruyama | Asao Katsume | Hiroshi Ohmori | Jun Ohkawa | J. Ohkawa | I. Maruyama | Y. Minatogawa | S. Toné | A. Katsume | H. Nuriya | Hiroshi Ohmori | H. Ohmori
[1] C C Howe,et al. Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. , 1980, Science.
[2] S. Shurtleff,et al. D-type cyclin-dependent kinase activity in mammalian cells , 1994, Molecular and cellular biology.
[3] F. Shibasaki,et al. Inhibition of Cytochrome c Release in Fas-mediated Signaling Pathway in Transgenic Mice Induced to Express Hepatitis C Viral Proteins* , 2001, The Journal of Biological Chemistry.
[4] H. Esche,et al. Formation of the early-region-2 transcription-factor-1-retinoblastoma-protein (E2F-1-RB) transrepressor and release of the retinoblastoma protein from nuclear complexes containing cyclin A is induced by interferon alpha in U937V cells but not in interferon-alpha-resistant U937VR cells. , 1997, European journal of biochemistry.
[5] D. Grandér,et al. Induction of Cip/Kip and Ink4 cyclin dependent kinase inhibitors by interferon-α in hematopoietic cell lines , 1997, Oncogene.
[6] K. Shimotohno,et al. Hepatitis C Virus Core Protein Inhibits Fas- and Tumor Necrosis Factor Alpha-Mediated Apoptosis via NF-κB Activation , 1999, Journal of Virology.
[7] T. Morizane,et al. Irregular regeneration of hepatocytes and risk of hepatocellular carcinoma in chronic hepatitis and cirrhosis with hepatitis-C-virus infection , 1998, The Lancet.
[8] S. Sugano,et al. Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase. , 1995, Nucleic acids research.
[9] Robert A. Weinberg,et al. Functional Inactivation of the Retinoblastoma Protein Requires Sequential Modification by at Least Two Distinct Cyclin-cdk Complexes , 1998, Molecular and Cellular Biology.
[10] M. Campo,et al. BPV-4 E8 transforms NIH3T3 cells, up-regulates cyclin A and cyclin A-associated kinase activity and de-regulates expression of the cdk inhibitor p27Kip1 , 1998, Oncogene.
[11] K. Meyer,et al. Hepatitis C virus core protein cooperates with ras and transforms primary rat embryo fibroblasts to tumorigenic phenotype , 1996, Journal of virology.
[12] K. Jeang,et al. Hepatitis C virus core protein‐induced loss of LZIP function correlates with cellular transformation , 2000, The EMBO journal.
[13] M. Kohara,et al. Simple fluorescent enzyme immunoassay for detection and quantification of hepatitis C viremia. , 1995, Journal of hepatology.
[14] M. Kohara,et al. Hepatitis C virus structural proteins induce liver cell injury in transgenic mice , 1999, Journal of medical virology.
[15] M. Honda,et al. Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus. , 2002, Gastroenterology.
[16] Yamamura Ken-ichi,et al. Efficient selection for high-expression transfectants with a novel eukaryotic vector , 1991 .
[17] R. Bartenschlager,et al. Sequences in the 5′ Nontranslated Region of Hepatitis C Virus Required for RNA Replication , 2001, Journal of Virology.
[18] L. Tsai,et al. p35, the Neuronal-specific Activator of Cyclin-dependent Kinase 5 (Cdk5) Is Degraded by the Ubiquitin-Proteasome Pathway* , 1998, The Journal of Biological Chemistry.
[19] C. Rice,et al. Efficient Replication of Hepatitis C Virus Genotype 1a RNAs in Cell Culture , 2003, Journal of Virology.
[20] J. Feramisco,et al. Microinjection of anti-p21 antibodies induces senescent Hs68 human fibroblasts to synthesize DNA but not to divide. , 1999, Cancer research.
[21] R. Kawaguchi,et al. Real-time detection system for quantification of hepatitis C virus genome. , 1999, Gastroenterology.
[22] M. Lai,et al. Hepatitis C Virus Core Protein Binds to the Cytoplasmic Domain of Tumor Necrosis Factor (TNF) Receptor 1 and Enhances TNF-Induced Apoptosis , 1998, Journal of Virology.
[23] Yoshiharu Matsuura,et al. The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice , 1998, Nature Medicine.
[24] R. Weinberg. E2F and Cell Proliferation: A World Turned Upside Down , 1996, Cell.
[25] H. Yonekawa,et al. Efficient Conditional Transgene Expression in Hepatitis C Virus cDNA Transgenic Mice Mediated by the Cre/loxP System* , 1998, The Journal of Biological Chemistry.
[26] L. Laimins,et al. Initiation of DNA synthesis by human papillomavirus E7 oncoproteins is resistant to p21-mediated inhibition of cyclin E-cdk2 activity , 1997, Journal of virology.
[27] T. Takegami,et al. Hepatitis C virus nonstructural protein NS3 transforms NIH 3T3 cells , 1995, Journal of virology.
[28] J. Hiscott,et al. Multiple signaling pathways leading to the activation of interferon regulatory factor 3. , 2002, Biochemical pharmacology.
[29] W. Voigt,et al. p53 and WAF1 are induced and Rb protein is hypophosphorylated during cell growth inhibition by the thymidylate synthase inhibitor ZD1694 (Tomudex). , 1997, Molecular pharmacology.
[30] J. Nevins,et al. A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[31] M. Oren,et al. Involvement of p21WAF1/Cip1, CDK4 and Rb in activin A mediated signaling leading to hepatoma cell growth inhibition , 1997, Oncogene.
[32] J. Silver,et al. Replication of Subgenomic Hepatitis C Virus Rnas in a Hepatoma Cell Line , 1999 .
[33] F. Sablitzky,et al. Inducible site-directed recombination in mouse embryonic stem cells. , 1996, Nucleic acids research.
[34] X. Graña,et al. Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs). , 1995, Oncogene.
[35] J. Nevins,et al. Role of the Rb/E2F pathway in cell growth control , 1997, Journal of cellular physiology.
[36] K. Taira,et al. Generality of the NUX rule: kinetic analysis of the results of systematic mutations in the trinucleotide at the cleavage site of hammerhead ribozymes. , 1995, Biochemistry.
[37] R. Metcalf,et al. p53 gene mutation and integrated hepatitis B viral DNA sequences in human liver cancer cell lines. , 1993, Carcinogenesis.
[38] D. Grandér,et al. Molecular mechanisms underlying interferon-α-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins , 1999, Oncogene.
[39] Katsuhiko Itoh,et al. Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas , 2000, Nature Medicine.
[40] Takeshi Tokuhisa,et al. Activation of STAT3 by the Hepatitis C Virus Core Protein Leads to Cellular Transformation , 2002, The Journal of experimental medicine.
[41] M. Lai,et al. Hepatitis C virus core protein interacts with the cytoplasmic tail of lymphotoxin-beta receptor , 1997, Journal of virology.
[42] M. Onji,et al. Hepatitis C virus infection is associated with the development of hepatocellular carcinoma. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[43] S. Thorgeirsson,et al. A retinoblastoma-binding protein that affects cell-cycle control and confers transforming ability , 1998, Nature Genetics.
[44] B. Spiegelman,et al. Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1 , 2001, Nature Medicine.
[45] J. Park,et al. Hepatitis C virus nonstructural protein NS4B transforms NIH3T3 cells in cooperation with the Ha-ras oncogene. , 2000, Biochemical and biophysical research communications.
[46] M. Ichikawa,et al. The Native Form and Maturation Process of Hepatitis C Virus Core Protein , 1998, Journal of Virology.
[47] T. Lee,et al. Doxorubicin-induced apoptosis and chemosensitivity in hepatoma cell lines , 2001, Cancer Chemotherapy and Pharmacology.
[48] Se-Hwan Yang,et al. Hepatitis C Virus Core from Two Different Genotypes Has an Oncogenic Potential but Is Not Sufficient for Transforming Primary Rat Embryo Fibroblasts in Cooperation with the H-ras Oncogene , 1998, Journal of Virology.
[49] J. Harbour,et al. Cdk Phosphorylation Triggers Sequential Intramolecular Interactions that Progressively Block Rb Functions as Cells Move through G1 , 1999, Cell.