论文信息 - Direct insulin algorithm for type 1 diabetes

Direct insulin algorithm for type 1 diabetes

Abstract We present a problem of controlling type 1 diabetes mellitus - a situation where plant is complex and dynamic, the measurements are sparse, and the data display erratic fluctuating behaviour. These characteristics make it very difficult to derive a model of the plant. We propose a model-free method of deriving a controller for this problem and discuss the limits of control performance under the constraints.

Iven Mareels | Lucia Santoso

[1] James C. Spall,et al. AN OVERVIEW OF THE SIMULTANEOUS PERTURBATION METHOD FOR EFFICIENT OPTIMIZATION , 1998 .

[2] W. F. Taylor,et al. Mean Amplitude of Glycemic Excursions, a Measure of Diabetic Instability , 1970, Diabetes.

[3] J. Nerup,et al. Glycosylated haemoglobin and steady-state mean blood glucose concentration in type 1 (insulin-dependent) diabetes , 1982, Diabetologia.

[4] Iven Mareels,et al. Markovian framework for diabetes control , 2001, Proceedings of the 40th IEEE Conference on Decision and Control (Cat. No.01CH37228).