Neuromedin B and its receptor are mitogens in both normal and malignant epithelial cells lining the colon.
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Sarah Glover | R. Benya | K. Matkowskyj | S. Glover | D. Matusiak | R. Nathaniel | Damien Matusiak | Rajkumar Nathaniel | Kristina Matkowskyj | Jianxin Yang | Richard V Benya | Jianxin Yang
[1] M. Moyer,et al. NCM460, a normal human colon mucosal epithelial cell line , 1996, In Vitro Cellular & Developmental Biology - Animal.
[2] R. Benya,et al. Phosphorylation of focal adhesion kinase tyrosine 397 critically mediates gastrin‐releasing peptide's morphogenic properties , 2004, Journal of cellular physiology.
[3] B. Yeğen. Bombesin-like peptides: candidates as diagnostic and therapeutic tools. , 2003, Current pharmaceutical design.
[4] Randal Cox,et al. Quantitative Immunohistochemistry by Measuring Cumulative Signal Strength Accurately Measures Receptor Number , 2003, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[5] R. Jensen,et al. Neuropeptides as autocrine growth factors in cancer cells. , 2003, Current pharmaceutical design.
[6] G. Rubin,et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[7] K. Wada,et al. Restraint stress impaired maternal behavior in female mice lacking the neuromedin B receptor (NMB-R) gene , 2002, Neuroscience Letters.
[8] K. Wada,et al. Decreased marble burying behavior in female mice lacking neuromedin-B receptor (NMB-R) implies the involvement of NMB/NMB-R in 5-HT neuron function , 2002, Brain Research.
[9] K. Wada,et al. Bombesin and its family of peptides: prospects for the treatment of obesity. , 2002, European journal of pharmacology.
[10] K. Wada,et al. Role of bombesin (BN)-like peptides/receptors in emotional behavior by comparison of three strains of BN-like peptide receptor knockout mice , 2002, Molecular Psychiatry.
[11] G. Cassano,et al. The proliferative response of HT-29 human colon adenocarcinoma cells to bombesin-like peptides. , 2001, Cancer letters.
[12] T. Gress,et al. GRP-receptor-mediated signal transduction, gene expression and DNA synthesis in the human pancreatic adenocarcinoma cell line HPAF , 2001, Peptides.
[13] R. Benya,et al. The case for gastrin-releasing peptide acting as a morphogen when it and its receptor are aberrantly expressed in cancer , 2001, Peptides.
[14] A. Schally,et al. The presence of receptors for bombesin/GRP and mRNA for three receptor subtypes in human ovarian epithelial cancers , 2000, Regulatory Peptides.
[15] A. Schally,et al. Presence of receptors for bombesin/gastrin‐releasing peptide and mRNA for three receptor subtypes in human prostate cancers , 2000, The Prostate.
[16] K A Matkowskyj,et al. Quantitative Immunohistochemistry by Measuring Cumulative Signal Strength Using Commercially Available Software Photoshop and Matlab , 2000, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[17] J. Primrose,et al. Bombesin family receptor and ligand gene expression in human colorectal cancer and normal mucosa , 1999, British Journal of Cancer.
[18] R. Benya,et al. Gastrin-releasing Peptide Is a Mitogen and a Morphogen in Murine Colon Cancer 1 , 2000 .
[19] J C Reubi,et al. Gastrin-releasing peptide receptors in non-neoplastic and neoplastic human breast. , 1999, The American journal of pathology.
[20] J. Siegfried,et al. Evidence for autocrine actions of neuromedin B and gastrin-releasing peptide in non-small cell lung cancer. , 1999, Pulmonary pharmacology & therapeutics.
[21] R. Benya,et al. Aberrant expression of gastrin-releasing peptide and its receptor by well-differentiated colon cancers in humans. , 1999, The American journal of physiology.
[22] P. Troncoso,et al. In situ hybridization for gastrin‐releasing peptide receptor (GRP receptor) expression in prostatic carcinoma , 1998, International journal of cancer.
[23] R. Jensen,et al. Neuromedin B receptor activation causes tyrosine phosphorylation of p125FAK by a phospholipase C independent mechanism which requires p21rho and integrity of the actin cytoskeleton. , 1997, Biochemistry.
[24] R. Jensen,et al. Discovery of a High Affinity Radioligand for the Human Orphan Receptor, Bombesin Receptor Subtype 3, Which Demonstrates That It Has a Unique Pharmacology Compared with Other Mammalian Bombesin Receptors* , 1997, The Journal of Biological Chemistry.
[25] G. Nussdorfer,et al. The role of neuromedin B in the regulation of rat pituitary-adrenocortical function. , 1996, Histology and histopathology.
[26] S. O’Grady,et al. Regulation of colonic ion transport by GRP. II. GRP modulates the epithelial response to PGE2. , 1996, The American journal of physiology.
[27] S. O’Grady,et al. Regulation of colonic ion transport by GRP. I. GRP stimulates transepithelial K and Na secretion. , 1996, The American journal of physiology.
[28] R. Jensen,et al. Expression and characterization of cloned human bombesin receptors. , 1995, Molecular pharmacology.
[29] R. Jensen,et al. Glycosylation of bombesin receptors: characterization, effect on binding, and G-protein coupling. , 1994, Biochemistry.
[30] Á. Hernanz,et al. Stimulation of natural killer and antibody-dependent cellular cytotoxicity activities in mouse leukocytes by bombesin, gastrin-releasing peptide and neuromedin C: Involvement of cyclic AMP, inositol 1,4,5-trisphosphate and protein kinase C , 1993, Journal of Neuroimmunology.
[31] R. Freshney,et al. Induction of phenotypic changes in SCLC cell lines in vitro by hexamethylene bisacetamide, sodium butyrate, and cyclic AMP. , 1993, Annals of oncology : official journal of the European Society for Medical Oncology.
[32] R. Jensen,et al. Characterization of bombesin receptors using a novel, potent, radiolabeled antagonist that distinguishes bombesin receptor subtypes. , 1993, Molecular pharmacology.
[33] R. Jensen,et al. Neuromedin B receptors retain functional expression when transfected into BALB 3T3 fibroblasts: analysis of binding, kinetics, stoichiometry, modulation by guanine nucleotide-binding proteins, and signal transduction and comparison with natively expressed receptors. , 1992, Molecular pharmacology.
[34] R. Jensen,et al. Development of a potent bombesin receptor antagonist with prolonged in vivo inhibitory activity on bombesin-stimulated amylase and protein release in the rat , 1992, Peptides.
[35] J. Battey,et al. Neuromedin B is present in lung cancer cell lines. , 1992, Cancer research.
[36] J. Polak,et al. Role of neuromedin B in control of the release of thyrotropin in hypothyroid and hyperthyroid rats. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[37] A. Gazdar,et al. Characterization of functional receptors for gastrointestinal hormones on human colon cancer cells. , 1992, Cancer research.
[38] R. Jensen,et al. Systematic development of bombesin/gastrin-releasing peptide antagonists. , 1992, Journal of the National Cancer Institute. Monographs.
[39] N. Bleehen,et al. Production of neuromedin B and neuromedin B gene expression in human lung tumor cell lines. , 1991, Cancer research.
[40] R. Jensen,et al. cDNA cloning, characterization, and brain region-specific expression of a neuromedin-B-preferring bombesin receptor , 1991, Neuron.
[41] J. Abita,et al. Characterization, in some human breast cancer cell lines, of gastrin‐releasing peptide‐like receptors which are absent in normal breast epithelial cells , 1990, International journal of cancer.
[42] R. Jensen,et al. Neuromedin B receptor in esophagus: evidence for subtypes of bombesin receptors. , 1989, The American journal of physiology.
[43] V. Erspamer. Discovery, Isolation, and Characterization of Bombesin‐like Peptides , 1988 .