Determinants of informal care time, distress, depression, and quality of life in care partners along the trajectory of Alzheimer's disease

We evaluated determinants associated with care partner outcomes along the Alzheimer's disease (AD) stages.

[1]  S. Levkoff,et al.  Dementia Neuropsychiatric Symptom Frequency, Severity, and Correlates in Community-Dwelling Thai Older Adults. , 2022, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

[2]  Anonymous,et al.  2022 Alzheimer's disease facts and figures , 2022, Alzheimer's & dementia : the journal of the Alzheimer's Association.

[3]  B. Husebø,et al.  Which factors increase informal care hours and societal costs among caregivers of people with dementia? A systematic review of Resource Utilization in Dementia (RUD) , 2021, Health Economics Review.

[4]  W. M. van der Flier,et al.  Neuropsychiatric and Cognitive Symptoms Across the Alzheimer Disease Clinical Spectrum , 2021, Neurology.

[5]  Xiangfei Meng,et al.  Effectiveness of caregiver non-pharmacological interventions for behavioural and psychological symptoms of dementia: An updated meta-analysis , 2021, Ageing Research Reviews.

[6]  W. M. van der Flier,et al.  Neuropsychiatric and Cognitive Symptoms Across the Alzheimer Disease Clinical Spectrum , 2021, Neurology.

[7]  W. M. van der Flier,et al.  Identifying relevant outcomes in the progression of Alzheimer's disease; what do patients and care partners want to know about prognosis? , 2021, Alzheimer's & dementia.

[8]  W. M. van der Flier,et al.  Dutch Brain Research Registry for study participant recruitment: Design and first results , 2021, Alzheimer's & dementia.

[9]  Yuan-Han Yang,et al.  The effects of caregiver characteristics on behavioral and psychological symptoms of dementia of patients with dementia , 2020, Aging & mental health.

[10]  W. M. van der Flier,et al.  Sex differences in CSF biomarkers vary by Alzheimer disease stage and APOE ε4 genotype , 2020, Neurology.

[11]  E. Grundy,et al.  Disease severity accounts for minimal variance of quality of life in people with dementia and their carers: analyses of cross-sectional data from the MODEM study , 2020, BMC Geriatrics.

[12]  Camille F. Chavan,et al.  How non-drug interventions affect the quality of life of patients suffering from progressive cognitive decline and their main caregiver , 2020, Aging.

[13]  Xiangping Liao,et al.  Factors associated with health‐related quality of life among family caregivers of people with Alzheimer's disease , 2020, Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society.

[14]  P. Lewczuk,et al.  Advantages and disadvantages of the use of the CSF Amyloid β (Aβ) 42/40 ratio in the diagnosis of Alzheimer’s Disease , 2019, Alzheimer's Research & Therapy.

[15]  S. Choi,et al.  Clinical and Demographic Predictors of Adverse Outcomes in Caregivers of Patients with Dementia , 2019, Dementia and neurocognitive disorders.

[16]  W. M. van der Flier,et al.  Nature and implications of sex differences in AD pathology , 2018, Nature Reviews Neurology.

[17]  D. Dorstyn,et al.  Alzheimers’ disease and caregiving: a meta-analytic review comparing the mental health of primary carers to controls , 2018, Aging & mental health.

[18]  G. Bączyk,et al.  Burden of caregivers of patients with Alzheimer's disease. , 2018, Scandinavian journal of caring sciences.

[19]  W. M. van der Flier,et al.  Association of Amyloid Positron Emission Tomography With Changes in Diagnosis and Patient Treatment in an Unselected Memory Clinic Cohort: The ABIDE Project , 2018, JAMA neurology.

[20]  Stephen F. Carter,et al.  The EMIF-AD PreclinAD study: study design and baseline cohort overview , 2018, Alzheimer's Research & Therapy.

[21]  Carol Duff,et al.  Dementia: assessment, management and support for people living with dementia and their carers , 2018 .

[22]  C. Jack,et al.  NIA-AA Research Framework: Toward a biological definition of Alzheimer’s disease , 2018, Alzheimer's & Dementia.

[23]  W. M. van der Flier,et al.  Amsterdam Dementia Cohort: Performing Research to Optimize Care , 2018, Journal of Alzheimer's disease : JAD.

[24]  W. M. van der Flier,et al.  Unbiased Approach to Counteract Upward Drift in Cerebrospinal Fluid Amyloid-β 1-42 Analysis Results. , 2018, Clinical chemistry.

[25]  Shyamal K. Das,et al.  Behavioural and Psychological Symptoms of Dementia: Correlates and Impact on Caregiver Distress , 2017, Dementia and Geriatric Cognitive Disorders Extra.

[26]  G. Livingston,et al.  Factors associated with the quality of life of family carers of people with dementia: A systematic review , 2017, Alzheimer's & Dementia.

[27]  Roy W Jones,et al.  How useful is the EQ-5D in assessing the impact of caring for people with Alzheimer’s disease? , 2017, Health and Quality of Life Outcomes.

[28]  P. Scheltens,et al.  Detecting functional decline from normal aging to dementia: Development and validation of a short version of the Amsterdam IADL Questionnaire , 2016, Alzheimer's & dementia.

[29]  G Ardine de Wit,et al.  Dutch Tariff for the Five-Level Version of EQ-5D. , 2016, Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research.

[30]  R. Ho,et al.  Prevalence of Mental Health Disorders Among Caregivers of Patients With Alzheimer Disease. , 2015, Journal of the American Medical Directors Association.

[31]  A. Koivisto,et al.  Depressed Spousal Caregivers Have Psychological Stress Unrelated to the Progression of Alzheimer Disease , 2015, Journal of geriatric psychiatry and neurology.

[32]  Li-ye Zhou,et al.  Measuring the Caregiver Burden of Caring for Community-Residing People with Alzheimer’s Disease , 2015, PloS one.

[33]  P. Scheltens,et al.  Diagnostic impact of CSF biomarkers for Alzheimer's disease in a tertiary memory clinic , 2015, Alzheimer's & Dementia.

[34]  D. Y. Lee,et al.  Multidimensional determinants of family caregiver burden in Alzheimer's disease , 2015, International Psychogeriatrics.

[35]  M. Medrano,et al.  Burden, anxiety and depression in caregivers of Alzheimer patients in the Dominican Republic , 2014, Dementia & neuropsychologia.

[36]  S. Teipel,et al.  Neuropsychiatric symptoms in people screened positive for dementia in primary care , 2014, International Psychogeriatrics.

[37]  F. Jessen Subjective and objective cognitive decline at the pre-dementia stage of Alzheimer’s disease , 2014, European Archives of Psychiatry and Clinical Neuroscience.

[38]  B. Vellas,et al.  Caregiver Burden in Alzheimer's Disease: Differential Associations in Adult-Child and Spousal Caregivers in the GERAS Observational Study , 2014, Dementia and Geriatric Cognitive Disorders Extra.

[39]  C. Lyketsos,et al.  Nonpharmacologic management of behavioral symptoms in dementia. , 2012, JAMA.

[40]  A. Gustavsson,et al.  Costs of care in a mild-to-moderate Alzheimer clinical trial sample: Key resources and their determinants , 2011, Alzheimer's & Dementia.

[41]  D. Coakley,et al.  Self-efficacy for managing dementia may protect against burden and depression in Alzheimer's caregivers , 2011, Aging & mental health.

[42]  J. Morris,et al.  The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease , 2011, Alzheimer's & Dementia.

[43]  Nick C Fox,et al.  The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease , 2011, Alzheimer's & Dementia.

[44]  B. Winblad,et al.  Relative importance of patient disease indicators on informal care and caregiver burden in Alzheimer's disease , 2010, International Psychogeriatrics.

[45]  J. Fleming,et al.  A consensus protocol for the standardization of cerebrospinal fluid collection and biobanking , 2009, Neurology.

[46]  M. Albert,et al.  Patient Dependence and Longitudinal Changes in Costs of Care in Alzheimer’s Disease , 2008, Dementia and Geriatric Cognitive Disorders.

[47]  Pierre-Marie Preux,et al.  Dementia patients caregivers quality of life: the PIXEL study , 2006, International journal of geriatric psychiatry.

[48]  Joan Wood,et al.  Patient and caregiver characteristics associated with depression in caregivers of patients with dementia , 2003, Journal of General Internal Medicine.

[49]  Martin Pinquart,et al.  Differences between caregivers and noncaregivers in psychological health and physical health: a meta-analysis. , 2003, Psychology and aging.

[50]  A. Mykletun,et al.  Hospital Anxiety and Depression (HAD) scale: Factor structure, item analyses and internal consistency in a large population , 2001, British Journal of Psychiatry.

[51]  J. Cummings,et al.  Validation of the NPI-Q, a brief clinical form of the Neuropsychiatric Inventory. , 2000, The Journal of neuropsychiatry and clinical neurosciences.

[52]  M. Irwin,et al.  Screening for depression in the older adult: criterion validity of the 10-item Center for Epidemiological Studies Depression Scale (CES-D) , 1999, Archives of internal medicine.

[53]  E. Tangalos,et al.  Mild Cognitive Impairment Clinical Characterization and Outcome , 1999 .

[54]  M. Caserta,et al.  Exploring the Caregiver Burden Inventory (CBI): Further Evidence for a Multidimensional View of Burden , 1996, International journal of aging & human development.

[55]  J. Gold,et al.  Validation of a combined comorbidity index. , 1994, Journal of clinical epidemiology.

[56]  R. Larsen,et al.  The Satisfaction with Life Scale , 1985, Journal of personality assessment.

[57]  S. Zarit,et al.  Relatives of the impaired elderly: correlates of feelings of burden. , 1980, The Gerontologist.

[58]  S. Folstein,et al.  "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. , 1975, Journal of psychiatric research.

[59]  W. Flier,et al.  Nature and implications of sex differences in AD pathology , 2019 .

[60]  B. Vellas,et al.  Analysis of burden in caregivers of people with Alzheimer’s disease using self-report and supervision hours , 2014, The journal of nutrition, health & aging.

[61]  Frederik Barkhof,et al.  Optimizing patient care and research: the Amsterdam Dementia Cohort. , 2014, Journal of Alzheimer's disease : JAD.

[62]  D. Selkoe Alzheimer's disease. , 2011, Cold Spring Harbor perspectives in biology.

[63]  A. Kasuya EuroQol--a new facility for the measurement of health-related quality of life. , 1990, Health policy.

[64]  Gesamtverband Deutscher Nervenärzte European archives of psychiatry and clinical neuroscience , 1990 .

[65]  V. Leirer,et al.  Development and validation of a geriatric depression screening scale: a preliminary report. , 1982, Journal of psychiatric research.