Microneedle arrays as transdermal and intradermal drug delivery systems: Materials science, manufacture and commercial development
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Ryan F. Donnelly | Eneko Larrañeta | Rebecca E. M. Lutton | Eneko Larrañeta | A. David Woolfson | R. Donnelly | A. Woolfson | E. Larrañeta
[1] Thakur Raghu Raj Singh,et al. Hydrogel-Forming Microneedle Arrays for Enhanced Transdermal Drug Delivery , 2012, Advanced functional materials.
[2] Hervé Bourhy,et al. Safety and efficacy of novel dermal and epidermal microneedle delivery systems for rabies vaccination in healthy adults. , 2010, Vaccine.
[3] A. Banga,et al. In vitro transdermal delivery of therapeutic antibodies using maltose microneedles. , 2009, International journal of pharmaceutics.
[4] Xiaoyun Hong,et al. Hydrogel Microneedle Arrays for Transdermal Drug Delivery , 2014 .
[5] Mark G. Allen,et al. Lack of pain associated with microfabricated microneedles. , 2001 .
[6] Hyungil Jung,et al. Drawing Lithography: Three‐Dimensional Fabrication of an Ultrahigh‐Aspect‐Ratio Microneedle , 2010, Advanced materials.
[7] G. Thouas,et al. Metallic implant biomaterials , 2015 .
[8] D. Irvine,et al. Releasable layer-by-layer assembly of stabilized lipid nanocapsules on microneedles for enhanced transcutaneous vaccine delivery. , 2012, ACS nano.
[9] Robert Q Frazer,et al. PMMA: an essential material in medicine and dentistry. , 2005, Journal of long-term effects of medical implants.
[10] James C. Birchall,et al. Microneedles in Clinical Practice–An Exploratory Study Into the Opinions of Healthcare Professionals and the Public , 2010, Pharmaceutical Research.
[11] T. Kenny,et al. What is the Young's Modulus of Silicon? , 2010, Journal of Microelectromechanical Systems.
[12] Alison Cowley,et al. A Healthy Future: Platinum in Medical Applications , 2011 .
[13] D. Liepmann,et al. Arrays of hollow out-of-plane microneedles for drug delivery , 2005, Journal of Microelectromechanical Systems.
[14] Viness Pillay,et al. Current advances in the fabrication of microneedles for transdermal delivery. , 2014, Journal of controlled release : official journal of the Controlled Release Society.
[15] Remo Guidieri. Res , 1995, RES: Anthropology and Aesthetics.
[16] J. Bouwstra,et al. Assembled microneedle arrays enhance the transport of compounds varying over a large range of molecular weight across human dermatomed skin. , 2007, Journal of controlled release : official journal of the Controlled Release Society.
[17] R. Pettis,et al. Microneedle delivery: clinical studies and emerging medical applications. , 2012, Therapeutic delivery.
[18] Yukako Ito,et al. Incidence of low bioavailability of leuprolide acetate after percutaneous administration to rats by dissolving microneedles. , 2011, International journal of pharmaceutics.
[19] E. Fernández,et al. Characterization of a novel calcium phosphate/sulphate bone cement. , 2002, Journal of biomedical materials research.
[20] Ryan F. Donnelly,et al. Microneedle-based drug delivery systems: Microfabrication, drug delivery, and safety , 2010, Drug delivery.
[21] Paula T Hammond,et al. Polymer multilayer tattooing for enhanced DNA vaccination. , 2013, Nature materials.
[22] Ryan F Donnelly,et al. Effects of microneedle length, density, insertion time and multiple applications on human skin barrier function: assessments by transepidermal water loss. , 2010, Toxicology in vitro : an international journal published in association with BIBRA.
[23] Shayne C. Gad,et al. Safety Evaluation in the Development of Medical Devices and Combination Products , 2008 .
[24] Lavanya K. Iyer,et al. Microarrays and microneedle arrays for delivery of peptides, proteins, vaccines and other applications , 2013, Expert opinion on drug delivery.
[25] B. Chichkov,et al. Pulsed laser deposition of antimicrobial silver coating on Ormocer® microneedles , 2009, Biofabrication.
[26] T. Eliades,et al. Cytotoxic effects of polycarbonate-based orthodontic brackets by activation of mitochondrial apoptotic mechanisms. , 2013, Dental materials : official publication of the Academy of Dental Materials.
[27] Angel Rodriguez,et al. Fabrication of silicon oxide microneedles from macroporous silicon , 2005 .
[28] Christopher H Contag,et al. Gene silencing following siRNA delivery to skin via coated steel microneedles: In vitro and in vivo proof-of-concept. , 2013, Journal of controlled release : official journal of the Controlled Release Society.
[29] M Navarro,et al. Biomaterials in orthopaedics , 2008, Journal of The Royal Society Interface.
[30] M. Hamidouche,et al. Thermal and mechanical characterization of borosilicate glass , 2009 .
[31] J. Bouwstra,et al. In vivo assessment of safety of microneedle arrays in human skin. , 2008, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[32] R. Pignatello. Biomaterials Applications for Nanomedicine , 2011 .
[33] Yuqin Qiu,et al. Controllable coating of microneedles for transdermal drug delivery , 2015, Drug development and industrial pharmacy.
[34] R. Donnelly,et al. Microneedle‐mediated intrascleral delivery of in situ forming thermoresponsive implants for sustained ocular drug delivery , 2014, The Journal of pharmacy and pharmacology.
[35] N. Roxhed,et al. Membrane-sealed hollow microneedles and related administration schemes for transdermal drug delivery , 2008, Biomedical microdevices.
[36] W. Ryu,et al. Perivascular biodegradable microneedle cuff for reduction of neointima formation after vascular injury. , 2014, Journal of controlled release : official journal of the Controlled Release Society.
[37] Jung-Hwan Park,et al. Dissolving microneedles for transdermal drug delivery. , 2008, Biomaterials.
[38] Robert Langer,et al. Differential degradation rates in vivo and in vitro of biocompatible poly(lactic acid) and poly(glycolic acid) homo- and co-polymers for a polymeric drug-delivery microchip , 2004, Journal of biomaterials science. Polymer edition.
[39] G. Leroux-Roels,et al. Seasonal influenza vaccine delivered by intradermal microinjection: A randomised controlled safety and immunogenicity trial in adults. , 2008, Vaccine.
[40] Ryan F. Donnelly,et al. A proposed model membrane and test method for microneedle insertion studies , 2014, International journal of pharmaceutics.
[41] M. Prausnitz,et al. Immunization by vaccine-coated microneedle arrays protects against lethal influenza virus challenge , 2009, Proceedings of the National Academy of Sciences.
[42] Mark G. Allen,et al. Polymer Microneedles for Controlled-Release Drug Delivery , 2006, Pharmaceutical Research.
[43] Aleksandr Ovsianikov,et al. The effects of geometry on skin penetration and failure of polymer microneedles , 2013, Journal of adhesion science and technology.
[44] Wijaya Martanto,et al. Microinfusion Using Hollow Microneedles , 2006, Pharmaceutical Research.
[45] J. Moan,et al. Microneedle Pre-treatment of Human Skin Improves 5-Aminolevulininc Acid (ALA)- and 5-Aminolevulinic Acid Methyl Ester (MAL)-Induced PpIX Production for Topical Photodynamic Therapy Without Increase in Pain or Erythema , 2010, Pharmaceutical Research.
[46] E. Fabrizio,et al. Sharp beveled tip hollow microneedle arrays fabricated by LIGA and 3D soft lithography with polyvinyl alcohol , 2006 .
[47] Ryan F Donnelly,et al. Review of patents on microneedle applicators. , 2011, Recent patents on drug delivery & formulation.
[48] Adam J. Davidson,et al. Transdermal drug delivery by coated microneedles: Geometry effects on effective skin thickness and drug permeability , 2008 .
[49] M. Madou. Fundamentals of microfabrication : the science of miniaturization , 2002 .
[50] J. McElnay,et al. Microneedle-Mediated Minimally Invasive Patient Monitoring , 2013, Therapeutic drug monitoring.
[51] Seajin Oh,et al. Dissolvable microneedle patches for the delivery of cell-culture-derived influenza vaccine antigens. , 2012, Journal of pharmaceutical sciences.
[52] Nicholas A Peppas,et al. Microfabricated drug delivery devices. , 2005, International journal of pharmaceutics.
[53] G. H. Clowes,et al. ON DICHLOROETHYLSULFIDE (MUSTARD GAS) IV. THE MECHANISM OF ABSORPTION BY THE SKIN , 1919 .
[54] Weien Yuan,et al. A scalable fabrication process of polymer microneedles , 2012, International journal of nanomedicine.
[55] Ryan F. Donnelly,et al. Innovative Strategies for Enhancing Topical and Transdermal Drug Delivery , 2007 .
[56] R. Scheuplein,et al. Mechanism of percutaneous absorption. II. Transient diffusion and the relative importance of various routes of skin penetration. , 1967, The Journal of investigative dermatology.
[57] Cheryl H. Dean,et al. Cutaneous Delivery of a Live, Attenuated Chimeric Flavivirus Vaccines against Japanese Encephalitis (ChimeriVaxTM-JE) in Non-Human Primates , 2005, Human vaccines.
[58] Wijaya Martanto,et al. Transdermal Delivery of Insulin Using Microneedles in Vivo , 2004, Pharmaceutical Research.
[59] C. Laurencin,et al. Biodegradable polymers as biomaterials , 2007 .
[60] Yeu-Chun Kim,et al. Formulation of Microneedles Coated with Influenza Virus-like Particle Vaccine , 2010, AAPS PharmSciTech.
[61] S. Ghanem,et al. Biodegradability, antimicrobial activity and properties of PVA/PVP hydrogels prepared by γ-irradiation , 2008 .
[62] M. B. Zimmerman,et al. Optimization of Impedance Spectroscopy Techniques for Measuring Cutaneous Micropore Formation after Microneedle Treatment in an Elderly Population , 2014, Pharmaceutical Research.
[63] Mark R Prausnitz,et al. Minimally Invasive Protein Delivery with Rapidly Dissolving Polymer Microneedles , 2008, Advanced materials.
[64] P. Laurent,et al. Evaluation of the clinical performance of a new intradermal vaccine administration technique and associated delivery system. , 2007, Vaccine.
[65] C. Meinhart,et al. Bulk Micromachined Titanium Microneedles , 2007, Journal of Microelectromechanical Systems.
[66] Yu Chong,et al. The mechanical properties of the skin epidermis in relation to targeted gene and drug delivery. , 2007, Biomaterials.
[67] Vinny R. Sastri. Plastics in Medical Devices: Properties, Requirements and Applications , 2010 .
[68] A. Luzardo-Álvarez,et al. Amoxicillin-Loaded Sponges Made of Collagen and Poly[(methyl vinyl ether)-co-(maleic anhydride)] for Root Canal Treatment: Preparation, Characterization and In Vitro Cell Compatibility , 2011, Journal of biomaterials science. Polymer edition.
[69] Peter J. Coassin,et al. Cyclic olefin polymers: innovative materials for high-density multiwell plates. , 2008, Assay and drug development technologies.
[70] Conor O'Mahony,et al. Coated microneedle arrays for transcutaneous delivery of live virus vaccines. , 2012, Journal of controlled release : official journal of the Controlled Release Society.
[71] Miss A.O. Penney. (b) , 1974, The New Yale Book of Quotations.
[72] Michael S Roberts,et al. Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin. , 2009, Journal of controlled release : official journal of the Controlled Release Society.
[73] J. Birchall,et al. Low temperature fabrication of biodegradable sugar glass microneedles for transdermal drug delivery applications. , 2012, Journal of controlled release : official journal of the Controlled Release Society.
[74] Maelíosa T. C. McCrudden,et al. Microneedles for intradermal and transdermal drug delivery. , 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[75] Zhang Yong,et al. Super-short solid silicon microneedles for transdermal drug delivery applications , 2010 .
[76] Albert P. Pisano,et al. Polymer investment molding: Method for fabricating hollow, microscale parts , 2007 .
[77] Diganta Bhusan Das,et al. Optimizing Microneedle Arrays to Increase Skin Permeability for Transdermal Drug Delivery , 2009, Annals of the New York Academy of Sciences.
[78] Joseph F Rizzo,et al. Biocompatibility of materials implanted into the subretinal space of Yucatan pigs. , 2006, Investigative ophthalmology & visual science.
[79] L. Ng,et al. Lights, Camera, and Action: Vertebrate Skin Sets the Stage for Immune Cell Interaction with Arthropod-Vectored Pathogens , 2013, Front. Immunol..
[80] 배호재. Microengineering과 줄기세포의 분화 , 2010 .
[81] BS Chandrashekar,et al. Acne Scar Subcision , 2010, Journal of cutaneous and aesthetic surgery.
[82] Manhee Han,et al. Influence of the delivery systems using a microneedle array on the permeation of a hydrophilic molecule, calcein. , 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[83] Bai Xu,et al. Controlled transdermal delivery of model drug compounds by MEMS microneedle array. , 2005, Nanomedicine : nanotechnology, biology, and medicine.
[84] Thakur Raghu Raj Singh,et al. Optical coherence tomography is a valuable tool in the study of the effects of microneedle geometry on skin penetration characteristics and in-skin dissolution. , 2010, Journal of controlled release : official journal of the Controlled Release Society.
[85] Maelíosa T. C. McCrudden,et al. Microneedle applications in improving skin appearance , 2015, Experimental dermatology.
[86] Kanji Takada,et al. Antigen-loaded dissolving microneedle array as a novel tool for percutaneous vaccination. , 2012, Vaccine.
[87] Keith D. Roby,et al. Innate immunity and the role of the antimicrobial peptide cathelicidin in inflammatory skin disease. , 2013, Drug discovery today. Disease mechanisms.
[88] Dorian Liepmann,et al. Microfabricated Polysilicon Microneedles for Minimally Invasive Biomedical Devices , 2000 .
[89] Suzanne S. Stensaas,et al. Histopathological evaluation of materials implanted in the cerebral cortex , 1978, Acta Neuropathologica.
[90] He Zhang,et al. In vitro and in vivo study of thymosin alpha1 biodegradable in situ forming poly(lactide-co-glycolide) implants. , 2010, International journal of pharmaceutics.
[91] Mark R Prausnitz,et al. Faster pharmacokinetics and increased patient acceptance of intradermal insulin delivery using a single hollow microneedle in children and adolescents with type 1 diabetes , 2013, Pediatric diabetes.
[92] B. Kim,et al. Treatment of Striae Distensae Using Needling Therapy: A Pilot Study , 2012, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].
[93] M. Lewandowska-Szumieł,et al. Interaction between tissues and implantable materials. , 2000, Frontiers of Medical and Biological Engineering.
[94] R. Luttge,et al. Micromolding for ceramic microneedle arrays , 2011 .
[95] アーネスト オレッティー,ジョン,et al. The drug delivery device , 1994 .
[96] R. Duncan,et al. Dextrins as potential carriers for drug targeting: tailored rates of dextrin degradation by introduction of pendant groups. , 2001, International journal of pharmaceutics.
[97] M. Gad-el-Hak. The MEMS Handbook , 2001 .
[98] K. Tam,et al. Biodegradable and biocompatible polyampholyte microgels derived from chitosan, carboxymethyl cellulose and modified methyl cellulose. , 2012, Carbohydrate polymers.
[99] N. Harvey,et al. Preclinical Evaluation of Microneedle Technology for Intradermal Delivery of Influenza Vaccines , 2007, Clinical and Vaccine Immunology.
[100] Brett E. Bouma,et al. A Bio-Inspired Swellable Microneedle Adhesive for Mechanical Interlocking with Tissue , 2013, Nature Communications.
[101] J. McElnay,et al. Children's views on microneedle use as an alternative to blood sampling for patient monitoring , 2014, The International journal of pharmacy practice.
[102] Mark R Prausnitz,et al. Precise microinjection into skin using hollow microneedles. , 2006, The Journal of investigative dermatology.
[103] Mark R Prausnitz,et al. Microneedles for transdermal drug delivery. , 2004, Advanced drug delivery reviews.
[104] Ryan F. Donnelly,et al. Hydrogel-Forming Microneedles Prepared from “Super Swelling” Polymers Combined with Lyophilised Wafers for Transdermal Drug Delivery , 2014, PloS one.
[105] M. Wirth,et al. Gantrez AN as a new polymer for the preparation of ligand-nanoparticle conjugates. , 2002, Journal of controlled release : official journal of the Controlled Release Society.
[106] J. Braybrook,et al. Biocompatibility assessment of medical devices and materials , 1997 .
[107] Leonard A. Smith,et al. An alternative approach to combination vaccines: intradermal administration of isolated components for control of anthrax, botulism, plague and staphylococcal toxic shock , 2008, Journal of immune based therapies and vaccines.
[108] M. Prausnitz,et al. Measles vaccination using a microneedle patch. , 2013, Vaccine.
[109] J. Hadem,et al. Assessment of xylitol serum levels during the course of parenteral nutrition including xylitol in intensive care patients: a case control study. , 2014, Clinical nutrition.
[110] C. Jérôme,et al. Chitosan-based biomaterials for tissue engineering , 2013 .
[111] Conor O'Mahony,et al. Structural characterization and in-vivo reliability evaluation of silicon microneedles , 2014, Biomedical Microdevices.
[112] Göran Stemme,et al. Side-opened out-of-plane microneedles for microfluidic transdermal liquid transfer , 2003 .
[113] M. Garland,et al. Electrically enhanced solute permeation across poly(ethylene glycol)-crosslinked poly(methyl vinyl ether-co-maleic acid) hydrogels: effect of hydrogel crosslink density and ionic conductivity. , 2011, International journal of pharmaceutics.
[114] Mark R Prausnitz,et al. Rapid pharmacokinetics of intradermal insulin administered using microneedles in type 1 diabetes subjects. , 2011, Diabetes technology & therapeutics.
[115] P. Dormitzer,et al. Influenza subunit vaccine coated microneedle patches elicit comparable immune responses to intramuscular injection in guinea pigs. , 2013, Vaccine.
[116] Seiji Aoyagi,et al. Laser fabrication of high aspect ratio thin holes on biodegradable polymer and its application to a microneedle , 2007 .
[117] M. Niinomi,et al. Titanium-Based Biomaterials for Preventing Stress Shielding between Implant Devices and Bone , 2011, International journal of biomaterials.
[118] Luca Wurfel,et al. Principles Of Tissue Engineering , 2016 .
[119] L. Chan,et al. Alginates as a useful natural polymer for microencapsulation and therapeutic applications , 2012 .
[120] A. Laurent,et al. Echographic measurement of skin thickness in adults by high frequency ultrasound to assess the appropriate microneedle length for intradermal delivery of vaccines. , 2007, Vaccine.
[121] Mark R Prausnitz,et al. Dissolving microneedle patch for transdermal delivery of human growth hormone. , 2011, Small.
[122] Mark R Prausnitz,et al. Insertion of microneedles into skin: measurement and prediction of insertion force and needle fracture force. , 2004, Journal of biomechanics.
[123] Yohei Mukai,et al. A low-invasive and effective transcutaneous immunization system using a novel dissolving microneedle array for soluble and particulate antigens. , 2012, Journal of controlled release : official journal of the Controlled Release Society.
[124] K. Sugibayashi,et al. Enhancement of skin permeation of high molecular compounds by a combination of microneedle pretreatment and iontophoresis. , 2007, Journal of controlled release : official journal of the Controlled Release Society.
[125] A. Tuantranont,et al. Design, Fabrication and Analysis of Silicon Hollow Microneedles for Transdermal Drug Delivery System for Treatment of Hemodynamic Dysfunctions , 2010, Cardiovascular engineering.
[126] Conor O'Mahony,et al. Determination of parameters for successful spray coating of silicon microneedle arrays. , 2011, International journal of pharmaceutics.
[127] Andrew G. Glen,et al. APPL , 2001 .
[128] K. Duffy,et al. Facial allergic granulomatous reaction and systemic hypersensitivity associated with microneedle therapy for skin rejuvenation. , 2014, JAMA dermatology.
[129] Cato T. Laurencin,et al. Polysaccharide biomaterials for drug delivery and regenerative engineering , 2014 .
[130] Diganta Bhusan Das,et al. Optimization of square microneedle arrays for increasing drug permeability in skin , 2008 .
[131] A. Ambrozaitis,et al. Immunogenicity, large scale safety and lot consistency of an intradermal influenza vaccine in adults aged 18–60 years: Randomized, controlled, Phase III trial , 2010, Human vaccines.
[132] M. Prausnitz,et al. Delivery of salmon calcitonin using a microneedle patch. , 2012, International journal of pharmaceutics.
[133] C. Shearwood,et al. Transdermal microneedles for drug delivery applications , 2006 .
[134] Mark R. Prausnitz,et al. Dissolving Polymer Microneedle Patches for Influenza Vaccination , 2010, Nature Medicine.
[135] G. G. Stokes. "J." , 1890, The New Yale Book of Quotations.
[136] Shekhar Bhansali,et al. Microneedle-Based Automated Therapy for Diabetes Mellitus , 2008, Journal of diabetes science and technology.
[137] Regina Luttge,et al. Applying ceramic nanoporous microneedle arrays as a transport interface in egg plants and an ex-vivo human skin model , 2012 .
[138] J. W. Wiechers,et al. The barrier function of the skin in relation to percutaneous absorption of drugs , 1989, Pharmaceutisch Weekblad.
[139] R. Legeros,et al. Properties of osteoconductive biomaterials: calcium phosphates. , 2002, Clinical orthopaedics and related research.
[140] J. Sung,et al. Transdermal delivery of cosmetic ingredients using dissolving polymer microneedle arrays , 2015, Biotechnology and Bioprocess Engineering.
[141] M. Allen,et al. Microfabricated microneedles: a novel approach to transdermal drug delivery. , 1998, Journal of pharmaceutical sciences.
[142] S. Zhai,et al. Microneedle pretreatment improves efficacy of cutaneous topical anesthesia. , 2010, The American journal of emergency medicine.
[143] D. Maisels,et al. Silicon granuloma of the skin and subcutaneous tissues. , 1966, American journal of surgery.
[144] Dorian Liepmann,et al. Microneedles and transdermal applications , 2007, Expert opinion on drug delivery.
[145] D. Banks,et al. Microengineering, MEMS, and Interfacing: A Practical Guide , 2006 .
[146] Mitsuhiro Shikida,et al. Fabrication of a hollow needle structure by dicing, wet etching and metal deposition , 2006 .
[147] Barjor Gimi,et al. In vitro and in vivo evaluation of SU-8 biocompatibility. , 2013, Materials science & engineering. C, Materials for biological applications.
[148] D. Das,et al. Permeability enhancement for transdermal delivery of large molecule using low-frequency sonophoresis combined with microneedles. , 2013, Journal of pharmaceutical sciences.
[149] A. Banga. Microporation applications for enhancing drug delivery , 2009, Expert opinion on drug delivery.
[150] Hyungil Jung,et al. An optimized hollow microneedle for minimally invasive blood extraction , 2013, Biomedical microdevices.
[151] Y. Izumi,et al. Calcium and silicon from bioactive glass concerned with formation of nodules in periodontal-ligament fibroblasts in vitro. , 1997, Journal of oral rehabilitation.
[152] C. O. Chichester,et al. Advances in food research , 1948 .
[153] Mark R. Prausnitz,et al. Layer-by-layer assembly of DNA- and protein-containing films on microneedles for drug delivery to the skin. , 2010, Biomacromolecules.
[154] Yong-Kyu Yoon,et al. Polymer particle-based micromolding to fabricate novel microstructures , 2007, Biomedical microdevices.
[155] Y. Demir,et al. Characterization of Polymeric Microneedle Arrays for Transdermal Drug Delivery , 2013, PloS one.
[156] Manhee Han,et al. A novel fabrication process for out-of-plane microneedle sheets of biocompatible polymer , 2007 .
[157] Takaya Miyano,et al. Sugar Micro Needles as Transdermic Drug Delivery System , 2005, Biomedical microdevices.
[158] Young Wook Choi,et al. Nanostructured lipid carrier-loaded hyaluronic acid microneedles for controlled dermal delivery of a lipophilic molecule , 2013, International journal of nanomedicine.
[159] J. Matriano,et al. Macroflux® Microprojection Array Patch Technology: A New and Efficient Approach for Intracutaneous Immunization , 2004, Pharmaceutical Research.
[160] Maelíosa T. C. McCrudden,et al. The role of microneedles for drug and vaccine delivery , 2014, Expert opinion on drug delivery.
[161] Ryan F. Donnelly,et al. Microwave‐Assisted Preparation of Hydrogel‐Forming Microneedle Arrays for Transdermal Drug Delivery Applications , 2015, Macromolecular materials and engineering.
[162] Mark R. Prausnitz,et al. Collection of Analytes from Microneedle Patches , 2014, Analytical chemistry.
[163] Ryan F. Donnelly,et al. Design, Optimization and Characterisation of Polymeric Microneedle Arrays Prepared by a Novel Laser-Based Micromoulding Technique , 2010, Pharmaceutical Research.
[164] J. Veciana,et al. Preparation of biodegradable poly (methyl vinyl ether-co-maleic anhydride) nanostructured microparticles by precipitation with a compressed antisolvent , 2010 .
[165] S. Kacew,et al. Toxicology of the Skin , 2009 .
[166] H. McCarthy,et al. Influence of skin model on in vitro performance of drug-loaded soluble microneedle arrays. , 2012, International journal of pharmaceutics.
[167] Aleksandr Ovsianikov,et al. Fabrication of microneedles using two photon polymerization for transdermal delivery of nanomaterials. , 2010, Journal of nanoscience and nanotechnology.
[168] Sang Jun Moon,et al. Fabrication of microneedle array using LIGA and hot embossing process , 2005 .
[169] Ryan F. Donnelly,et al. Skin Dendritic Cell Targeting via Microneedle Arrays Laden with Antigen-Encapsulated Poly-d,l-lactide-co-Glycolide Nanoparticles Induces Efficient Antitumor and Antiviral Immune Responses , 2013, ACS nano.
[170] Ryan F. Donnelly,et al. Microneedle Arrays Allow Lower Microbial Penetration Than Hypodermic Needles In Vitro , 2009, Pharmaceutical Research.
[171] Ji Hoon Jeong,et al. Polyplex-releasing microneedles for enhanced cutaneous delivery of DNA vaccine. , 2014, Journal of controlled release : official journal of the Controlled Release Society.
[172] J. Bouwstra,et al. Improved piercing of microneedle arrays in dermatomed human skin by an impact insertion method. , 2008, Journal of controlled release : official journal of the Controlled Release Society.
[173] Yohei Mukai,et al. Transcutaneous immunization using a dissolving microneedle array protects against tetanus, diphtheria, malaria, and influenza. , 2012, Journal of controlled release : official journal of the Controlled Release Society.
[174] Phosphate and cell growth on nanostructured semiconductors , 1997 .
[175] H. Engqvist,et al. Self-setting bioceramic microscopic protrusions for transdermal drug delivery. , 2014, Journal of materials chemistry. B.
[176] J. Liu,et al. Modeling of transdermal drug delivery with a microneedle array , 2006 .
[177] P. McCarron,et al. Microneedles/Delivery Device and Method , 2007 .
[178] N. Wilke,et al. Process optimization and characterization of silicon microneedles fabricated by wet etch technology , 2005, Microelectron. J..
[179] Akira Yamamoto,et al. The development and characteristics of novel microneedle arrays fabricated from hyaluronic acid, and their application in the transdermal delivery of insulin. , 2012, Journal of controlled release : official journal of the Controlled Release Society.
[180] Y Noishiki,et al. Tissue biocompatibility of cellulose and its derivatives. , 1989, Journal of biomedical materials research.
[181] G. Fabbrocini,et al. Acne scarring treatment using skin needling , 2009, Clinical and experimental dermatology.
[182] A. Fahr,et al. Skin penetration enhancement by a microneedle device (Dermaroller) in vitro: dependency on needle size and applied formulation. , 2009, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[183] Shekhar Bhansali,et al. Sharpening of hollow silicon microneedles to reduce skin penetration force , 2010 .
[184] Ryan F. Donnelly,et al. Microneedle-mediated Transdermal and Intradermal Drug Delivery , 2012 .
[185] Michael J Akers,et al. Excipient-drug interactions in parenteral formulations. , 2002, Journal of pharmaceutical sciences.
[186] J. Irache,et al. Cytotoxicity and cell interaction studies of bioadhesive poly(anhydride) nanoparticles for oral antigen/drug delivery. , 2013, Journal of biomedical nanotechnology.
[187] H. Maibach,et al. Textbook of Cosmetic Dermatology , 1998 .
[188] M. Kietzmann,et al. Microneedle pretreatment enhances the percutaneous permeation of hydrophilic compounds with high melting points , 2012, BMC Pharmacology and Toxicology.
[189] Lutz Heinemann,et al. Intradermal microneedle delivery of insulin lispro achieves faster insulin absorption and insulin action than subcutaneous injection. , 2011, Diabetes technology & therapeutics.
[190] Ryan F. Donnelly,et al. Design and physicochemical characterisation of novel dissolving polymeric microneedle arrays for transdermal delivery of high dose, low molecular weight drugs , 2014, Journal of controlled release : official journal of the Controlled Release Society.
[191] Mark R Prausnitz,et al. Minimally invasive extraction of dermal interstitial fluid for glucose monitoring using microneedles. , 2005, Diabetes technology & therapeutics.
[192] M. Niinomi. Biologically and Mechanically Biocompatible Titanium Alloys , 2008 .
[193] Conor O'Mahony,et al. Hydrogel-forming microneedle arrays exhibit antimicrobial properties: potential for enhanced patient safety. , 2013, International journal of pharmaceutics.
[194] Conor O'Mahony,et al. Processing difficulties and instability of carbohydrate microneedle arrays , 2009, Drug development and industrial pharmacy.
[195] Keizo Fukushima,et al. Two-layered dissolving microneedles formulated with intermediate-acting insulin. , 2012, International journal of pharmaceutics.
[196] M. Kim,et al. Novel cosmetic patches for wrinkle improvement: retinyl retinoate‐ and ascorbic acid‐loaded dissolving microneedles , 2014, International journal of cosmetic science.
[197] Mark G. Allen,et al. Hollow metal microneedles for insulin delivery to diabetic rats , 2005, IEEE Transactions on Biomedical Engineering.
[198] W. R. Runyan,et al. Semiconductor integrated circuit processing technology , 1990 .
[199] Antonio Fábio,et al. Polymer , 2018, Definitions.
[200] Firas Sammoura,et al. Polymeric microneedle fabrication using a microinjection molding technique , 2007 .
[201] Mark G. Allen,et al. Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: Fabrication methods and transport studies , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[202] S. Moreira,et al. In Vivo Biocompatibility and Biodegradability of Dextrin-based Hydrogels , 2010 .
[203] Bastian Brand,et al. Biocompatibility and resorption of a brushite calcium phosphate cement. , 2005, Biomaterials.
[204] W. Moreau. Semiconductor Lithography: Principles, Practices, and Materials , 1987 .
[205] O. Lindahl,et al. Polymer-Based Microfluidic Devices for Pharmacy, Biology and Tissue Engineering , 2012 .
[206] F. de Looze,et al. Intradermal influenza vaccine administered using a new microinjection system produces superior immunogenicity in elderly adults: a randomized controlled trial. , 2008, The Journal of infectious diseases.
[207] J. Irache,et al. Thermosensitive hydrogels of poly(methyl vinyl ether-co-maleic anhydride) - Pluronic(®) F127 copolymers for controlled protein release. , 2014, International journal of pharmaceutics.
[208] Muthukumaran Packirisamy,et al. BioMEMS: Science and Engineering Perspectives , 2011 .
[209] Dong-il Dan Cho,et al. In-plane single-crystal-silicon microneedles for minimally invasive microfluid systems , 2004 .
[210] G. Holzapfel,et al. Penetration-Enhanced Ultrasharp Microneedles and Prediction on Skin Interaction for Efficient Transdermal Drug Delivery , 2007, Journal of Microelectromechanical Systems.
[211] Mark R Prausnitz,et al. Coated microneedles for transdermal delivery. , 2007, Journal of controlled release : official journal of the Controlled Release Society.
[212] Mahmoud Ameri,et al. Transdermal delivery of desmopressin using a coated microneedle array patch system. , 2004, Journal of controlled release : official journal of the Controlled Release Society.
[213] Petras Juzenas,et al. Microneedle Arrays Permit Enhanced Intradermal Delivery of a Preformed Photosensitizer , 2009, Photochemistry and photobiology.
[214] M. Lewandowska-Szumieł,et al. Aluminium release as a new factor in the estimation of alumina bioceramic implants. , 1990, Clinical materials.
[215] Mark R Prausnitz,et al. Microneedle patches: usability and acceptability for self-vaccination against influenza. , 2014, Vaccine.
[216] H. McCarthy,et al. Influence of a pore‐forming agent on swelling, network parameters, and permeability of poly(ethylene glycol)‐crosslinked poly(methyl vinyl ether‐co‐maleic acid) hydrogels: Application in transdermal delivery systems , 2012 .
[217] Marina Andreiotelli,et al. Are ceramic implants a viable alternative to titanium implants? A systematic literature review. , 2009, Clinical oral implants research.
[218] J. Irache,et al. Toxicity Studies of Poly(Anhydride) Nanoparticles as Carriers for Oral Drug Delivery , 2012, Pharmaceutical Research.
[219] Shekhar Bhansali,et al. Axial and shear fracture strength evaluation of silicon microneedles , 2010 .
[220] Sang Jun Moon,et al. A novel fabrication method of a microneedle array using inclined deep x-ray exposure , 2005 .
[221] Robert Langer,et al. Transdermal drug delivery , 2008, Nature Biotechnology.
[222] D. Liepmann,et al. In vivo evaluation of a microneedle-based miniature syringe for intradermal drug delivery , 2009, Biomedical microdevices.
[223] Kanji Takada,et al. Feasibility of microneedles for percutaneous absorption of insulin. , 2006, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[224] N. Nezafati,et al. Preparation and characterization of calcium sulfate-biomimetic apatite nanocomposites for controlled release of antibiotics. , 2009, Journal of biomedical materials research. Part B, Applied biomaterials.
[225] M. Prausnitz,et al. Microneedle delivery of an M2e-TLR5 ligand fusion protein to skin confers broadly cross-protective influenza immunity. , 2014, Journal of controlled release : official journal of the Controlled Release Society.
[226] Abigail Beckel. Hum , 2017 .
[227] Jung-Hwan Park,et al. Microneedles for drug and vaccine delivery. , 2012, Advanced drug delivery reviews.
[229] Chien-Chung Fu,et al. Different fabrication methods of out-of-plane polymer hollow needle arrays and their variations , 2007 .
[230] A. Shetty,et al. Evaluation of Microneedling Fractional Radiofrequency Device for Treatment of Acne Scars , 2014, Journal of cutaneous and aesthetic surgery.
[231] Satish Doddaballapur,et al. Microneedling with Dermaroller , 2009, Journal of cutaneous and aesthetic surgery.
[232] L. Yahia,et al. Comparative in vitro biocompatibility of nickel-titanium, pure nickel, pure titanium, and stainless steel: genotoxicity and atomic absorption evaluation. , 1999, Bio-medical materials and engineering.
[233] Mark R. Prausnitz,et al. Coating Formulations for Microneedles , 2007, Pharmaceutical Research.
[234] Clive G. Wilson,et al. Laser-engineered dissolving microneedles for active transdermal delivery of nadroparin calcium. , 2012, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[235] James C Birchall,et al. Microneedle delivery of plasmid DNA to living human skin: Formulation coating, skin insertion and gene expression. , 2012, Journal of controlled release : official journal of the Controlled Release Society.
[236] Wijaya Martanto,et al. Mechanism of fluid infusion during microneedle insertion and retraction. , 2006, Journal of controlled release : official journal of the Controlled Release Society.
[237] Seong Ho Kang,et al. Improvement in antigen-delivery using fabrication of a grooves-embedded microneedle array , 2009 .
[238] Vincent J. Sullivan,et al. Microneedle-Based Intradermal Delivery of the Anthrax Recombinant Protective Antigen Vaccine , 2006, Infection and Immunity.
[239] Regina Luttge,et al. Silicon micromachined hollow microneedles for transdermal liquid transport , 2003 .
[240] Manisha Joshi,et al. Synthesis and Characterization of Metallic Gel Complexes Derived from Carboxymethyl Cellulose , 2013 .
[241] M. Petrtýl,et al. Surface modification of cyclic olefin copolymers for osteochondral defect repair can increase pro-destructive potential of human chondrocytes in vitro. , 2010, Physiological research.
[242] Göran Stemme,et al. Painless Drug Delivery Through Microneedle-Based Transdermal Patches Featuring Active Infusion , 2008, IEEE Transactions on Biomedical Engineering.
[243] Yu-Chung N Cheng,et al. Biocompatibilities of sapphire and borosilicate glass as cortical neuroprostheses. , 2007, Magnetic resonance imaging.
[244] Ryan F. Donnelly,et al. Considerations in the sterile manufacture of polymeric microneedle arrays , 2015, Drug Delivery and Translational Research.
[245] Mark R Prausnitz,et al. Microneedles permit transdermal delivery of a skin-impermeant medication to humans , 2008, Proceedings of the National Academy of Sciences.
[246] G. Kotzar,et al. Evaluation of MEMS materials of construction for implantable medical devices. , 2002, Biomaterials.
[247] K. Horch,et al. Biocompatibility of silicon-based electrode arrays implanted in feline cortical tissue. , 1993, Journal of biomedical materials research.
[248] B. Chichkov,et al. Two photon induced polymerization of organic-inorganic hybrid biomaterials for microstructured medical devices. , 2006, Acta biomaterialia.
[249] Shankar Chandrasekaran,et al. Surface micromachined metallic microneedles , 2003 .
[250] M. Shikida,et al. Differences in anisotropic etching properties of KOH and TMAH solutions , 2000 .
[251] Zhenguo Liu,et al. Dissolving and biodegradable microneedle technologies for transdermal sustained delivery of drug and vaccine , 2013, Drug design, development and therapy.
[252] J. Matriano,et al. Parathyroid Hormone (1-34)-Coated Microneedle Patch System: Clinical Pharmacokinetics and Pharmacodynamics for Treatment of Osteoporosis , 2010, Pharmaceutical Research.
[253] J A Planell,et al. Calcium phosphate cements as bone drug delivery systems: a review. , 2006, Journal of controlled release : official journal of the Controlled Release Society.
[254] Yong-Kyu Yoon,et al. An electrically active microneedle array for electroporation , 2010, Biomedical microdevices.
[255] I. Majid. Microneedling Therapy in Atrophic Facial Scars: An Objective Assessment , 2009, Journal of cutaneous and aesthetic surgery.
[256] Herbert Wolter,et al. Synthesis, properties and applications of inorganic–organic copolymers (ORMOCER®s) , 1999 .
[257] A. Kissenpfennig,et al. Microneedle-mediated vaccine delivery: Harnessing cutaneous immunobiology to improve efficacy , 2012, Expert opinion on drug delivery.
[258] M. Prausnitz,et al. Transdermal Influenza Immunization with Vaccine-Coated Microneedle Arrays , 2009, PloS one.
[259] Jung-Hwan Park,et al. Biodegradable polymer microneedles: fabrication, mechanics and transdermal drug delivery. , 2005, Journal of controlled release : official journal of the Controlled Release Society.
[260] Hyungil Jung,et al. Dissolving microneedles for transdermal drug administration prepared by stepwise controlled drawing of maltose. , 2011, Biomaterials.
[261] Barbara D Boyan,et al. A review of polyvinyl alcohol and its uses in cartilage and orthopedic applications. , 2012, Journal of biomedical materials research. Part B, Applied biomaterials.
[262] G. Tiram,et al. Administration, distribution, metabolism and elimination of polymer therapeutics. , 2012, Journal of controlled release : official journal of the Controlled Release Society.
[263] J. Yoshimitsu,et al. Self-dissolving microneedles for the percutaneous absorption of EPO in mice , 2006, Journal of drug targeting.
[264] M. Kendall,et al. Targeted, needle-free vaccinations in skin using multilayered, densely-packed dissolving microprojection arrays. , 2010, Small.
[265] Ying Zhang,et al. Development of Lidocaine-Coated Microneedle Product for Rapid, Safe, and Prolonged Local Analgesic Action , 2011, Pharmaceutical Research.
[266] Ericka Stricklin-Parker,et al. Ann , 2005 .
[267] Conor O'Mahony,et al. Hydrogel‐Forming and Dissolving Microneedles for Enhanced Delivery of Photosensitizers and Precursors , 2014, Photochemistry and photobiology.
[268] S. Nakagawa,et al. Vaccine efficacy of transcutaneous immunization with amyloid β using a dissolving microneedle array in a mouse model of Alzheimer's disease , 2014, Journal of Neuroimmunology.
[269] Mark R Prausnitz,et al. Fabrication of dissolving polymer microneedles for controlled drug encapsulation and delivery: Bubble and pedestal microneedle designs. , 2010, Journal of pharmaceutical sciences.
[270] Boris N. Chichkov,et al. Two Photon Polymerization of Polymer–Ceramic Hybrid Materials for Transdermal Drug Delivery , 2007 .
[271] Boris N. Chichkov,et al. Three-Dimensional Cell Growth on Structures Fabricated from ORMOCER® by Two-Photon Polymerization Technique , 2007, Journal of biomaterials applications.
[272] D. Puleo,et al. Calcium sulfate: a review. , 2005, Journal of long-term effects of medical implants.
[273] Furio Gramatica,et al. Poly vinyl alcohol re-usable masters for microneedle replication , 2009 .
[274] M. Prausnitz,et al. Minimally invasive insulin delivery in subjects with type 1 diabetes using hollow microneedles. , 2009, Diabetes technology & therapeutics.
[275] Scott A. Burton,et al. Rapid Intradermal Delivery of Liquid Formulations Using a Hollow Microstructured Array , 2010, Pharmaceutical Research.
[276] N. Pandis,et al. Bisphenol-A and residual monomer leaching from orthodontic adhesive resins and polycarbonate brackets: a systematic review. , 2013, American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics.
[277] Priyanka Ghosh,et al. Challenges and opportunities in dermal/transdermal delivery. , 2010, Therapeutic delivery.
[278] Hyungil Jung,et al. Drawing lithography for microneedles: a review of fundamentals and biomedical applications. , 2012, Biomaterials.
[279] Hirenkumar K. Makadia,et al. Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier. , 2011, Polymers.
[280] D. Bozentka. Biological performance of materials: fundamentals of biocompatibility , 1993 .
[281] Rebecca S. Shawgo,et al. Biocompatibility and biofouling of MEMS drug delivery devices. , 2003, Biomaterials.
[282] Chandra Sekhar Kolli,et al. Characterization of Solid Maltose Microneedles and their Use for Transdermal Delivery , 2007, Pharmaceutical Research.