Comparison study of two different patient-controlled anesthesia regiments after cardiac surgery.

INTRODUCTION Acute and severe pain is frequent in patients who undergo cardiothoracic surgery. Patient controlled analgesia (PCA) can be used to manage postoperative pain. OBJECTIVE To compare analgesia of morphine PCA alone without continuous infusion with morphine PCA plus a continuous infusion on postoperative period after cardiac surgery and to evaluate pain scores, morphine consumption, number of demand, patient satisfaction and side effects. METHODS Randomized trial was conducted to assess patients who underwent cardiac surgery receiving either morphine PCA alone or morphine PCA plus continuous infusion. In the post operative period, PCA was started at extubation in both regiments according to randomization. Pain intensity, morphine consumption, number of demand, satisfaction and side effects were assessed at zero, six, twelve, eighteen, twenty four and thirty hours after patients' extubation. RESULTS The study enrolled 100 patients. 50 patients received morphine PCA alone, (Group A) and 50 patients received morphine PCA plus a background infusion, (Group B). Group B patients had less demand, consumed more morphine and were more satisfied regarding analgesia. No statistical differences were shown between groups related to pain intensity, and side effects. CONCLUSIONS Pain control was effective and similar in both groups. Morphine PCA alone seems to be better for postoperative pain manage in cardiac surgery, due to its less morphine expense with the same effectiveness.

[1]  Víctor A. Contreras-Domínguez,et al.  Analgesia controlada pelo paciente reduz consumo de bupivacaína no bloqueio femoral no tratamento da dor pós-operatória após reconstrução do ligamento cruzado anterior do joelho , 2007 .

[2]  F. Chung,et al.  Patient-controlled transdermal fentanyl hydrochloride vs intravenous morphine pump for postoperative pain: a randomized controlled trial. , 2004, JAMA.

[3]  U. Aypar,et al.  A background infusion of morphine does not enhance postoperative analgesia after cardiac surgery , 2003, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

[4]  M. Choinière,et al.  Efficacy and Costs of Patient-Controlled Analgesia versus Regularly Administered Intramuscular Opioid Therapy , 1999 .

[5]  J. Boldt,et al.  Pain management in cardiac surgery patients: comparison between standard therapy and patient-controlled analgesia regimen. , 1998, Journal of cardiothoracic and vascular anesthesia.

[6]  K. Egan,et al.  Patient satisfaction with intravenous PCA or epidural morphine , 1994, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

[7]  N. Morton,et al.  Comparison of patient-controlled analgesia with and without a background infusion after lower abdominal surgery in children. , 1993, British journal of anaesthesia.

[8]  P. White,et al.  Effects of a nighttime opioid infusion with PCA therapy on patient comfort and analgesic requirements after abdominal hysterectomy. , 1992, Anesthesiology.

[9]  R. Mckenzie,et al.  A787 COMPARISON OF PCA ALONE AND PCA WITH CONTINUOUS INFUSION ON PAIN RELIEF AND QUALITY OF SLEEP , 1990 .

[10]  H. R. Vinik,et al.  PATIENT CONTROLLED ANALGESIA (PCA) COMBINED WITH CONTINUOUS INFUSION (CI) , 1990 .

[11]  L E Mather,et al.  Variables of patient‐controlled analgesia 2. concurrent infusion , 1989, Anaesthesia.

[12]  R. Likert Rensis Likert on managing human assets. , 1978, Bulletin on training, trends, techniques, topics.

[13]  M. Hockstein A Background Infusion of Morphine Enhances Patient-controlled Analgesia After Cardiac Surgery , 2006 .

[14]  C. Bast,et al.  Patient-controlled analgesia. , 1986, Nursing.