PC12 Pheochromocytoma Cultures in Neurobiological Research

[1]  L. Greene,et al.  Genomic and non-genomic actions of nerve growth factor in development. , 1983, Progress in brain research.

[2]  L. Greene,et al.  Nerve growth factor-induced neuronal differentiation of PC12 pheochromocytoma cells: Lack of inhibition by a tumor promoter , 1982, Brain Research.

[3]  A. Tischler,et al.  Content and release of neurotensin in PC12 pheochromocytoma cell cultures: modulation by dexamethasone and nerve growth factor , 1982, Regulatory Peptides.

[4]  L. Greene,et al.  MECHANISTIC STUDIES ON THE CELLULAR EFFECTS OF NERVE GROWTH FACTOR , 1982 .

[5]  G. Guroff,et al.  Increased Levels of Neuron‐Specific Enolase in PC 12 Pheochromocytoma Cells as a Result of Nerve Growth Factor Treatment , 1982, Journal of neurochemistry.

[6]  Virginia M. Y. Lee,et al.  Identification of neural and adrenal medullary surface membrane glycoproteins recognized by antisera to cultured rat sympathetic neurons and PC12 pheochromocytoma cells , 1981, Neuroscience.

[7]  H. Hatanaka,et al.  Nerve growth factor-mediated stimulation of tyrosine hydroxylase activity in a clonal rat pheochromocytoma cell line , 1981, Brain Research.

[8]  G. Dickens,et al.  The Induction of Ornithine Decarboxylase by Nerve Growth Factor and Epidermal Growth Factor in PC 12 Cells , 1981, Journal of neurochemistry.

[9]  W. Melega,et al.  Choline and acetylcholine metabolism in PC12 secretory cells. , 1981, Biochemistry.

[10]  Paul C. Letourneau.  Immunocytochemical evidence for colocalization in neurite growth cones of actin and myosin and their relationship to cell--substratum adhesions. , 1981, Developmental biology.

[11]  K. Unsicker,et al.  Differential effects of cyclic AMP and cholera toxin on nerve growth factor-induced neurite outgrowth from adrenal medullary chromaffin and pheochromocytoma cells. , 1981, Brain research.

[12]  L. Greene,et al.  Pit formation and rapid changes in surface morphology of sympathetic neurons in response to nerve growth factor , 1981, The Journal of cell biology.

[13]  W. Stallcup,et al.  Two types of potassium channels in the PC12 cell line , 1981, Brain Research.

[14]  L. Greene,et al.  Regulation of acetylcholinesterase activity by nerve growth factor. Role of transcription and dissociation from effects on proliferation and neurite outgrowth. , 1981, The Journal of biological chemistry.

[15]  James Cohen,et al.  A neuronal cell-surface antigen is found in the CNS but not in peripheral neurones , 1981, Nature.

[16]  T. Vulliamy,et al.  Cell-surface antigen distinguishes sensory and autonomic peripheral neurones from central neurones , 1981, Nature.

[17]  M. Bothwell,et al.  Nerve growth factor receptors on PC12 cells: Evidence for two receptor classes with differing cytoskeletal association , 1981, Cell.

[18]  E. Shooter,et al.  Differential and synergistic actions of nerve growth factor and cyclic AMP in PC12 cells , 1981, The Journal of cell biology.

[19]  W. Stallcup,et al.  Rubidium efflux from neural cell lines through voltage-dependent potassium channels. , 1981, Developmental biology.

[20]  E. Shooter,et al.  Nerve growth factor-induced differentiation of PC12 cells: evaluation of changes in RNA and DNA metabolism , 1981, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[21]  Y. Akamatsu,et al.  Presence of the phospholipid methylation pathway in mammalian cultured cells. , 1981, Biochimica et biophysica acta.

[22]  J. Boonstra,et al.  Rapid effects of nerve growth factor on the Na+, K+-pump in rat pheochromocytoma cells. , 1981, Experimental cell research.

[23]  D. Reis,et al.  Translation of tyrosine hydroxylase from poly(A)-mRNA in pheochromocytoma cells is enhanced by dexamethasone. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[24]  G. Guroff,et al.  Nerve growth factor-induced alteration in the response of PC12 pheochromocytoma cells to epidermal growth factor , 1981, The Journal of cell biology.

[25]  D. Schubert,et al.  The role of cAMP in the induction of ornithine decarboxylase by nerve and epidermal growth factors , 1981, Journal of neuroscience research.

[26]  R. Tschannen,et al.  Strain and host-cell dependence of vaccinia virus proteins. , 2005, European journal of biochemistry.

[27]  R. Miller,et al.  Distribution of [Met5]- and [Leu5]-enkephalin-, vasoactive intestinal polypeptide- and substance P-like immunoreactivities in human adrenal glands , 1980, Neuroscience.

[28]  L. Greene,et al.  Characterization of antisera raised against cultured rat sympathetic neurons , 1980, Neuroscience.

[29]  G. Guroff,et al.  Increased phosphorylation of specific nuclear proteins in superior cervical ganglia and PC12 cells in response to nerve growth factor. , 1980, The Journal of biological chemistry.

[30]  L. Greene,et al.  Differential cytotoxic activities of antisera against nerve growth factor-treated and untreated clonal pheochromocytoma cells , 1980, Neuroscience.

[31]  A. Tischler,et al.  Nerve growth factor-induced neurite outgrowth from normal human chromaffin cells. , 1980, Laboratory investigation; a journal of technical methods and pathology.

[32]  H. Herschman,et al.  Tumor promoter modulation of epidermal growth factor‐ and nerve growth factor‐induced adhesion and growth factor binding of PC‐12 pheochromocytoma cells , 1980, Journal of cellular physiology.

[33]  J. Patrick,et al.  Nerve growth factor mediates phosphorylation of specific proteins , 1980, Cell.

[34]  K. M. Vaughn,et al.  Clonal variants of PC12 pheochromocytoma cells with altered response to nerve growth factor , 1980, Cell.

[35]  E. Shooter,et al.  Nerve growth factor receptors on PC12 cells: ligand-induced conversion from low- to high-affinity states. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[36]  U. Otten,et al.  Permissive action of glucocorticoids in induction of tyrosine hydroxylase by nerve growth factor in a pheochromocytoma cell line , 1980, Brain Research.

[37]  S. U. Kim,et al.  Isolation and characterization of chromaffin granules from a pheochromocytoma (PC 12) cell line. , 1980, Experimental cell research.

[38]  G. Kreutzberg,et al.  Regulation of acetylcholinesterase by nerve growth factor in the pheochromocytoma PC12 cell line , 1980, Neuroscience Letters.

[39]  E. Neufeld,et al.  Mobility, clustering, and transport of nerve growth factor in embryonal sensory cells and in a sympathetic neuronal cell line. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[40]  M. Shelanski,et al.  Interaction of nerve growth factor with pheochromocytoma cells. Evidence for tight binding and sequestration , 1980, Neuroscience.

[41]  J. Foidart,et al.  Collagen synthesis in cultures of differentiating neural crest cells. , 1980, Cell differentiation.

[42]  F. Klier,et al.  The modulation of neurotransmitter synthesis by steroid hormones and insulin , 1980, Brain Research.

[43]  L. Greene,et al.  The effects of nerve growth factor on acetylcholinesterase and its multiple forms in cultures of rat PC12 pheochromocytoma cells: increased total specific activity and appearance of the 16 S molecular form. , 1980, Developmental biology.

[44]  L. Toll,et al.  Storage of dopamine and acetylcholine in granules of PC12, a clonal pheochromocytoma cell line. , 1980, Biochemistry.

[45]  L. Toll,et al.  Evidence that an ATPase and a protonmotive force function in the transport of acetylcholine into storage vesicles. , 1980, The Journal of biological chemistry.

[46]  L. Naldini,et al.  Intracellular distribution of nerve growth factor in rat pheochromocytoma PC12 cells: evidence for a perinuclear and intranuclear location. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[47]  P. O'lague,et al.  Physiological and morphological studies of rat pheochromocytoma cells (PC12) chemically fused and grown in culture. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[48]  H. Herschman,et al.  Epidermal growth factor induces tyrosine hydroxylase in a clonal pheochromocytoma cell line, PC-G2 , 1980, The Journal of cell biology.

[49]  R. Bunge,et al.  Morphological and biochemical studies on the development of cholinergic properties in cultured sympathetic neurons. II. Dependence on postnatal age , 1980, The Journal of cell biology.

[50]  S. Rufini,et al.  Black widow spider toxin-induced calcium fluxes and transmitter release in a neurosecretory cell line , 1980, Nature.

[51]  H. Hatanaka,et al.  A clonal rat pheochromocytoma cell line possesses synthesizing ability of γ-aminobutyric acid together with catecholamine and acetylcholine , 1980, Brain Research.

[52]  J. Fong,et al.  Purification and Characterization of Rat Pheochromocytoma Dopamine β‐Hydroxylase , 1980 .

[53]  L. Greene,et al.  Stimulation by nerve growth factor of specific protein synthesis in rat PC12 pheochromocytoma cells , 1980, Neuroscience.

[54]  Binding properties of a neurotoxin from the venom of the green mamba, Dendroaspis viridis. , 1980, The Journal of biological chemistry.

[55]  S. Pfeiffer,et al.  Thy-1 cell surface antigen on cloned nerve cell lines of the rat and mouse: Amount, location and origin of the antigen on the cells , 1980, Brain Research.

[56]  R. Olsen,et al.  GABA and picrotoxinin receptors in clonal nerve cells , 1980, Nature.

[57]  E. Shooter,et al.  Ca2+ transmembrane fluxes and nerve growth factor action on a clonal cell line of rat phaeochromocytoma , 1980, Nature.

[58]  H. Thoenen,et al.  Nerve Growth Factor: Biological Significance, Measurement and Distribution , 1980, Journal of neurochemistry.

[59]  D. Loegering,et al.  Cytotoxic effects of the guinea pig eosinophil major basic protein on tracheal epithelium. , 1980, Laboratory investigation; a journal of technical methods and pathology.

[60]  Factors influencing transmitter type in sympathetic ganglion cells. , 1980, Advances in biochemical psychopharmacology.

[61]  L. Greene,et al.  Phenotypic plasticity of pheochromocytoma and normal adrenal medullary cells. , 1980, Advances in biochemical psychopharmacology.

[62]  Comparisons of nerve fiber growth from three major catecholamine-producing cell systems: adrenal medulla, superior cervical ganglion, and locus coeruleus. , 1980, Advances in biochemical psychopharmacology.

[63]  E. Shooter,et al.  The nerve growth factor: biochemistry, synthesis, and mechanism of action. , 1980, Annual review of neuroscience.

[64]  J. Patrick,et al.  Substance P enhances cholinergic receptor desensitization in a clonal nerve cell line. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[65]  L. Shenkman,et al.  Purification and characterization of tyrosine hydroxylase from a clonal pheochromocytoma cell line. , 1980, Molecular pharmacology.

[66]  K. Unsicker,et al.  Effects of cell culture conditions, nerve growth factor, dexamethasone, and cyclic AMP on adrenal chromaffin cells in vitro. , 1980, Advances in biochemical psychopharmacology.

[67]  M. Fauquet,et al.  Acetylcholine synthesis by mesencephalic neural crest cells in the process of migration in vivo , 1979, Nature.

[68]  R. W. Gundersen,et al.  Neuronal chemotaxis: chick dorsal-root axons turn toward high concentrations of nerve growth factor. , 1979, Science.

[69]  J. Connolly,et al.  Rapid, sequential changes in surface morphology of PC12 pheochromocytoma cells in response to nerve growth factor , 1979, The Journal of cell biology.

[70]  J. Garrels,et al.  Modulation of protein synthesis by nerve growth factor. , 1979, The Journal of biological chemistry.

[71]  L. Greene,et al.  Fine structure of initial outgrowth of processes induced in a pheochromocytoma cell line (PC12) by nerve growth factor , 1979, Journal of neurocytology.

[72]  T. Hökfelt,et al.  Enkephalin- and somatostatin-like immunoreactivities in human adrenal medulla and pheochromocytoma. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[73]  G. Guroff,et al.  Nerve growth factor-induced reduction in epidermal growth factor responsiveness and epidermal growth factor receptors in PC12 cells: an aspect of cell differentiation. , 1979, Biochemical and biophysical research communications.

[74]  H. Thoenen,et al.  Induction of fibre outgrowth and choline acetyltransferase in PC12 pheochromocytoma cells by conditioned media from glial cells and organ extracts. , 1979, Experimental cell research.

[75]  H. Thoenen,et al.  Regulation of tyrosine hydroxylase and choline acetyltransferase activities by cell density in the PC12 rat pheochromocytoma clonal cell line. , 1979, Experimental cell research.

[76]  H. Thoenen,et al.  Properties of the nerve growth factor receptor of a clonal line of rat pheochromocytoma (PC12) cells. , 1979, Experimental cell research.

[77]  L. Greene,et al.  Rapid stimulation by nerve growth factor of amino acid uptake by clonal PC12 pheochromocytoma cells. , 1979, The Journal of biological chemistry.

[78]  R. Seeger,et al.  Onco-neural antigen: a new neural differentiation antigen expressed by neuroblastoma, oat cell carcinoma, Wilms' tumor, and sarcoma cells. , 1979, Journal of immunology.

[79]  R. Levi‐montalcini,et al.  Nerve growth factor-induced transformation of immature chromaffin cells in vivo into sympathetic neurons: effect of antiserum to nerve growth factor. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[80]  E. Shooter,et al.  Nerve growth factor in the nucleus: interaction with receptors on the nuclear membrane. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[81]  L. Greene,et al.  Nerve growth factor in the goldfish brain: biological assay studies using pheochromocytoma cells , 1979, Brain Research.

[82]  Y. Nakazato,et al.  THE EFFECT OF VERATRIDINE ON THE RELEASE OF CATECHOLAMINES FROM THE PERFUSED ADRENAL GLAND , 1979, British journal of pharmacology.

[83]  W. Stallcup.  Sodium and calcium fluxes in a clonal nerve cell line. , 1979, The Journal of physiology.

[84]  A. K. Ritchie.  Catecholamine secretion in a rat pheochromocytoma cell line: two pathways for calcium entry. , 1979, The Journal of physiology.

[85]  G H Sato,et al.  Growth of a rat neuroblastoma cell line in serum-free supplemented medium. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[86]  L. Greene,et al.  Evidence for RNA synthesis-dependent and -independent pathways in stimulation of neurite outgrowth by nerve growth factor. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[87]  L. Greene,et al.  Induction of ornithine decarboxylase by nerve growth factor dissociated from effects on survival and neurite outgrowth , 1978, Nature.

[88]  D. Schubert.  NGF-induced alternations in protein secretion and substrate-attached material of a clonal nerve cell line , 1978, Brain Research.

[89]  H. Thoenen,et al.  Selective enzyme induction in a nerve growth factor-responsive pheochromocytoma cell line (PC 12) , 1978, Brain Research.

[90]  L. Greene,et al.  NGF stimulates incorporation of fucose or glucosamine into an external glycoprotein in cultured rat PC12 pheochromocytoma cells , 1978, Cell.

[91]  H. Herschman,et al.  Nerve growth factor-mediated induction of tyrosine hydroxylase in a clonal pheochromocytoma cell line. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[92]  LA Greene,et al.  Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium , 1978, The Journal of cell biology.

[93]  H. Thoenen,et al.  Nerve growth factor‐mediated selective induction of ornithine decarboxylase in rat pheochromocytoma; a cyclic amp‐independent process , 1978, FEBS letters.

[94]  L. Greene,et al.  Morphologic and cytochemical properties of a clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. , 1978, Laboratory investigation; a journal of technical methods and pathology.

[95]  H. Thoenen,et al.  Nerve growth factor-induced fiber outgrowth from isolated rat adrenal chromaffin cells: impairment by glucocorticoids. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[96]  H. Thoenen,et al.  Glucocorticoid induction of tyrosine hydroxylase in a continous cell line of rat pheochromocytoma , 1978, The Journal of cell biology.

[97]  D. Schubert,et al.  Alterations in the surface properties of cells responsive to nerve growth factor , 1978, Nature.

[98]  L. Greene,et al.  SHORT‐TERM REGULATION OF CATECHOLAMINE BIOSYNTHESIS IN A NERVE GROWTH FACTOR RESPONSIVE CLONAL LINE OF RAT PHEOCHROMOCYTOMA CELLS , 1978, Journal of neurochemistry.

[99]  P. Patterson.  Environmental determination of autonomic neurotransmitter functions. , 1978, Annual review of neuroscience.

[100]  S. Pais.  Angiographic demonstration of a vasoactive intestinal polypeptide-secreting pheochromocytoma in a patient with WDHA syndrome. , 1978, AJR. American journal of roentgenology.

[101]  W. Chieh-ping.  Adrenal medullary hyperplasia. , 1978, Chinese medical journal.

[102]  L. Greene,et al.  Release of [3H]norepinephrine from a clonal line of pheochromocytoma cells (PC12) by nicotinic cholinergic stimulation , 1977, Brain Research.

[103]  J. Patrick,et al.  alpha-Bungarotoxin binding and cholinergic receptor function on a rat sympathetic nerve line. , 1977, The Journal of biological chemistry.

[104]  L. Greene,et al.  Ascorbic acid transport by a clonal line of pheochromocytoma cells , 1977, Brain Research.

[105]  L. Greene,et al.  Specific neural and adrenal medullary antigens detected by antisera to clonal PC12 pheochromocytoma cells. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[106]  D. Schubert,et al.  Storage and release of acetylcholine by a clonal cell line. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[107]  J. Lakshmanan,et al.  Nerve growth factor increases activity of ornithine decarboxylase in superior cervical ganglia of young rats. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[108]  J. Patrick,et al.  Immunological distinction between acetylcholine receptor and the alpha-bungarotoxin-binding component on sympathetic neurons. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[109]  L. Greene.  A quantitative bioassay for nerve growth factor (NGF) activity employing a clonal pheochromocytoma cell line , 1977, Brain Research.

[110]  D. Schubert,et al.  Alteration of cellular adhesion by nerve growth factor. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[111]  L. Greene,et al.  Nerve growth factor-induced increase in electrical excitability and acetylcholine sensitivity of a rat pheochromocytoma cell line , 1977, Nature.

[112]  L. Greene,et al.  Synthesis, storage and release of acetylcholine by a noradrenergic pheochromocytoma cell line , 1977, Nature.

[113]  L. Greene,et al.  Release, storage and uptake of catecholamines by a clonal cell line of nerve growth factor (NGF) responsive pheochromocytoma cells , 1977, Brain Research.

[114]  S. Heinemann,et al.  Cholinergic metabolism and synapse formation by a rat nerve cell line. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[115]  L. Greene,et al.  Neuroendocrine neoplasms and their cells of origin. , 1977, The New England journal of medicine.

[116]  Z. Horii,et al.  Nerve growth factor action on membrane permeation to exogenous substrates in dorsal root ganglionic dissociates from the chick embryo , 1977, Brain Research.

[117]  S. Hagiwara,et al.  Action potentials in the rat chromaffin cell and effects of acetylcholine. , 1976, The Journal of physiology.

[118]  J. Richards,et al.  Ultrastructural cytochemistry of biogenic amines in nervous tissue: methodologic improvements. , 1976, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[119]  A. Tischler,et al.  Electrical excitability of cultured adrenal chromaffin cells. , 1976, The Journal of physiology.

[120]  C. Byus,et al.  Proposed model of major sequential biochemical events of a trophic response. , 1976, Life sciences.

[121]  L. Greene,et al.  Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[122]  A. Tischler,et al.  Neural properties of cultured human endocrine tumor cells of proposed neural crest origin. , 1976, Science.

[123]  H. Wolfe,et al.  Adrenal medullary hyperplasia. A morphometric analysis in patients with familial medullary thyroid carcinoma. , 1976, The American journal of pathology.

[124]  L. Greene,et al.  Nerve growth factor-induced process formation by cultured rat pheochromocytoma cells , 1975, Nature.

[125]  S. Said,et al.  Elevated plasma and tissue levels of vasoactive intestinal polypeptide in the watery-diarrhea syndrome due to pancreatic, bronchogenic and other tumors. , 1975, The New England journal of medicine.

[126]  J. Carney,et al.  Bilateral adrenal medullary hyperplasia in multiple endocrine neoplasia, type 2: the precursor of bilateral pheochromocytoma. , 1975, Mayo Clinic proceedings.

[127]  E. Yavin,et al.  ATTACHMENT AND CULTURE OF DISSOCIATED CELLS FROM RAT EMBRYO CEREBRAL HEMISPHERES ON POLYLYSINE-COATED SURFACE , 1974, The Journal of cell biology.

[128]  Actions of GABA, picrotoxin and bicuculline on adrenal medulla. , 1974, European journal of pharmacology.

[129]  F. Merk,et al.  Ultrastructure and in vitro growth characteristics of a transplantable rat pheochromocytoma , 1973, Cancer.

[130]  M. Kadin,et al.  Comparison of pheochromocytes with ganglion cells and neuroblasts grown in vitro. An electron microscopic and histochemical study , 1971, Cancer.

[131]  L. Elfvin.  The development of the secretory granules in the rat adrenal medulla. , 1967, Journal of ultrastructure research.

[132]  A. Pearse.  Common cytochemical properties of cells producing polypeptide hormones, with particular reference to calcitonin and the thyroid C cells , 1966, Veterinary Record.

[133]  M. Grillo.  C. ELECTRON MICROSCOPY OF SYMPATHETIC TISSUES , 1966 .

[134]  R. Gibson.  A COMPREHENSIVE GERIATRIC SERVICE BASED ON A GENERAL HOSPITAL.. , 1965, Lancet.

[135]  Bornstein Mb,et al.  Reconstituted rattail collagen used as substrate for tissue cultures on coverslips in Maximow slides and roller tubes. , 1958, Laboratory investigation; a journal of technical methods and pathology.

[136]  M. Mcmillan.  Identification of hydroxytyramine in a chromaffin tumour. , 1956, Lancet.