SERS Biomedical Applications: Diagnostics, Forensics, and Metabolomics

Abstract This review summarizes the use of a surface-enhanced Raman spectroscopy (SERS)-based platform for a number of biomedical analytic applications ranging from infectious disease diagnostics to forensic science. There is an urgent need to develop rapid, sensitive, simple, and reliable method for the identification of pathogens and to meet recognized unmet technological needs in the forensic community. The use of a SERS methodology for the rapid detection and identification of bacterial clinical isolates in urine at minimal clinical levels demonstrates how this optical approach can provide rapid (

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