Relevance of induced and accidental hypothermia after trauma-haemorrhage–what do we know from experimental models in pigs?

[1]  M. Huber-Lang,et al.  Combined Hemorrhage/Trauma Models in Pigs—Current State and Future Perspectives , 2013, Shock.

[2]  T. Gerlach,et al.  A pilot study of the use of kaolin-impregnated gauze (Combat Gauze) for packing high-grade hepatic injuries in a hypothermic coagulopathic swine model. , 2013, The Journal of surgical research.

[3]  M. Georgieff,et al.  Effects of Pretreatment Hypothermia During Resuscitated Porcine Hemorrhagic Shock , 2013, Critical care medicine.

[4]  L. Blackbourne,et al.  In vivo assessment of the Combat Ready Clamp to control junctional hemorrhage in swine , 2013, The journal of trauma and acute care surgery.

[5]  S. Ruchholtz,et al.  Induced hypothermia does not impair coagulation system in a swine multiple trauma model , 2013, The journal of trauma and acute care surgery.

[6]  J. Differding,et al.  The use of lyophilized plasma in a severe multi‐injury pig model , 2013, Transfusion.

[7]  W. Ding,et al.  Temporary rapid bowel ligation as a damage control adjunct improves survival in a hypothermic traumatic shock swine model with multiple bowel perforations. , 2013, The Journal of surgical research.

[8]  C. Krettek,et al.  Effects of accidental hypothermia on posttraumatic complications and outcome in multiple trauma patients. , 2013, Injury.

[9]  S. Ruchholtz,et al.  A Combined Trauma Model of Chest and Abdominal Trauma With Hemorrhagic Shock—Description of a New Porcine Model , 2012, Shock.

[10]  G. Beilman,et al.  Environmental Hypothermia in Porcine Polytrauma and Hemorrhagic Shock is Safe , 2012, Shock.

[11]  M. Cohen,et al.  Animal models of trauma-induced coagulopathy. , 2012, Thrombosis research.

[12]  M. van Griensven,et al.  Facts and Fiction: The Impact of Hypothermia on Molecular Mechanisms following Major Challenge , 2012, Mediators of inflammation.

[13]  R. Lefering,et al.  Hypothermia for Prediction of Death in Severely Injured Blunt Trauma Patients , 2012, Shock.

[14]  P. Rhee,et al.  Intracorporeal use of advanced local hemostatics in a damage control swine model of grade IV liver injury. , 2011, The Journal of trauma.

[15]  R. Rossaint,et al.  Prothrombin complex concentrate reduces blood loss and enhances thrombin generation in a pig model with blunt liver injury under severe hypothermia , 2011, Thrombosis and Haemostasis.

[16]  J. Differding,et al.  Lyophilized plasma with ascorbic acid decreases inflammation in hemorrhagic shock. , 2011, The Journal of trauma.

[17]  P. Rhee,et al.  A new survivable damage control model including hypothermia, hemodilution, and liver injury. , 2011, Journal of Surgical Research.

[18]  Thomas H Fischer,et al.  Development and testing of low-volume hyperoncotic, hyperosmotic spray-dried plasma for the treatment of trauma-associated coagulopathy. , 2011, The Journal of trauma.

[19]  G. Velmahos,et al.  Hemostatic and pharmacologic resuscitation: results of a long-term survival study in a swine polytrauma model. , 2011, The Journal of trauma.

[20]  L. Blackbourne,et al.  Clot-inducing minerals versus plasma protein dressing for topical treatment of external bleeding in the presence of coagulopathy. , 2010, The Journal of trauma.

[21]  G. Beilman,et al.  Hypothermia is associated with improved outcomes in a porcine model of hemorrhagic shock. , 2010, The Journal of trauma.

[22]  M. Georgieff,et al.  Cardiac and metabolic effects of hypothermia and inhaled hydrogen sulfide in anesthetized and ventilated mice* , 2010, Critical care medicine.

[23]  L. Blackbourne,et al.  Safety evaluation of new hemostatic agents, smectite granules, and kaolin-coated gauze in a vascular injury wound model in swine. , 2010, The Journal of trauma.

[24]  D. Mozingo.  Use of a modified chitosan dressing in a hypothermic coagulopathic grade V liver injury model , 2010 .

[25]  W. Ding,et al.  Temporary intravascular shunting improves survival in a hypothermic traumatic shock swine model with superior mesenteric artery injuries. , 2010, Surgery.

[26]  R. Rossaint,et al.  A New Model for Blunt Liver Injuries in the Swine , 2009, European Surgical Research.

[27]  Michael J. Duggan,et al.  Testing of blood products in a polytrauma model: results of a multi-institutional randomized preclinical trial. , 2009, The Journal of trauma.

[28]  J. Differding,et al.  Lyophilized plasma for resuscitation in a swine model of severe injury. , 2009, Archives of surgery.

[29]  W. Ding,et al.  Establishment of an acute superior mesenteric artery injury model for damage control surgery. , 2009, The Journal of surgical research.

[30]  Michael J. Duggan,et al.  REPRODUCIBILITY OF AN ANIMAL MODEL SIMULATING COMPLEX COMBAT-RELATED INJURY IN A MULTIPLE-INSTITUTION FORMAT , 2009, Shock.

[31]  T. Fischer,et al.  Development and testing of freeze-dried plasma for the treatment of trauma-associated coagulopathy. , 2008, The Journal of trauma.

[32]  M. Dubick,et al.  Thrombelastography is better than PT, aPTT, and activated clotting time in detecting clinically relevant clotting abnormalities after hypothermia, hemorrhagic shock and resuscitation in pigs. , 2008, The Journal of trauma.

[33]  G. Velmahos,et al.  Putting life on hold-for how long? Profound hypothermic cardiopulmonary bypass in a Swine model of complex vascular injuries. , 2008, The Journal of trauma.

[34]  G. Dickneite,et al.  Characterization of the Coagulation Deficit in Porcine Dilutional Coagulopathy and Substitution with a Prothrombin Complex Concentrate , 2008, Anesthesia and analgesia.

[35]  C. Wade,et al.  A novel biologic hemostatic dressing (fibrin patch) reduces blood loss and resuscitation volume and improves survival in hypothermic, coagulopathic Swine with grade V liver injury. , 2008, The Journal of trauma.

[36]  D. R. Brown,et al.  Active internal re-warming using a centrifugal pump and heat exchanger following haemorrhagic shock, surgical trauma and hypothermia in a porcine model. , 2007, Injury.

[37]  P. Rhee,et al.  Profound hypothermic cardiopulmonary bypass facilitates survival without a high complication rate in a swine model of complex vascular, splenic, and colon injuries. , 2007, Journal of the American College of Surgeons.

[38]  S. Stern,et al.  Effects of ethanol on limited resuscitation in a model of traumatic brain injury and hemorrhagic shock. , 2006, Journal of neurosurgery.

[39]  P. Rhee,et al.  Profound hypothermia is superior to ultraprofound hypothermia in improving survival in a swine model of lethal injuries. , 2006, Surgery.

[40]  Richard A. Harris,et al.  Damage control management of experimental grade 5 renal injuries: further evaluation of FloSeal gelatin matrix. , 2006, The Journal of trauma.

[41]  Eduardo C. Ayuste,et al.  Does the rate of rewarming from profound hypothermic arrest influence the outcome in a swine model of lethal hemorrhage? , 2006, The Journal of trauma.

[42]  D. King,et al.  Early vasopressin improves short-term survival after pulmonary contusion. , 2005, The Journal of trauma.

[43]  P. Giannoudis,et al.  Effects of hypothermia and re-warming on the inflammatory response in a murine multiple hit model of trauma. , 2005, Cytokine.

[44]  Eduardo C. Ayuste,et al.  Induction of profound hypothermia modulates the immune/inflammatory response in a swine model of lethal hemorrhage. , 2005, Resuscitation.

[45]  K. Ryan,et al.  Effect of recombinant FVIIa in hypothermic, coagulopathic pigs with liver injuries. , 2005, The Journal of trauma.

[46]  J. Holcomb,et al.  Independent contributions of hypothermia and acidosis to coagulopathy in swine. , 2005, The Journal of trauma.

[47]  S. Wisniewski,et al.  Mild hypothermia improves survival after prolonged, traumatic hemorrhagic shock in pigs. , 2004, The Journal of trauma.

[48]  P. Giannoudis,et al.  Impact of hypothermia on the immunologic response after trauma and elective surgery. , 2005, Surgical technology international.

[49]  P. Rhee,et al.  The rate of induction of hypothermic arrest determines the outcome in a Swine model of lethal hemorrhage. , 2004, The Journal of trauma.

[50]  Peter Rhee,et al.  Application of a zeolite hemostatic agent achieves 100% survival in a lethal model of complex groin injury in Swine. , 2004, The Journal of trauma.

[51]  P. Giannoudis,et al.  Pathophysiologic changes and effects of hypothermia on outcome in elective surgery and trauma patients. , 2004, American journal of surgery.

[52]  T. Sakamoto,et al.  Effect of induced-hypothermia on short-term survival after volume-controlled hemorrhage in pigs. , 2003, Resuscitation.

[53]  W. Voelckel,et al.  Vasopressin, but Not Fluid Resuscitation, Enhances Survival in a Liver Trauma Model with Uncontrolled and Otherwise Lethal Hemorrhagic Shock in Pigs , 2003, Anesthesiology.

[54]  W. Vandertop,et al.  Effects of therapeutic hypothermia on intracranial pressure and outcome in patients with severe head injury , 2002, Intensive Care Medicine.

[55]  J. Holcomb,et al.  The effect of recombinant factor VIIa on coagulopathic pigs with grade V liver injuries. , 2002, The Journal of trauma.

[56]  T. Sakamoto,et al.  Rapid body cooling by cold fluid infusion prolongs survival time during uncontrolled hemorrhagic shock in pigs. , 2002, The Journal of trauma.

[57]  R. Hahn,et al.  Induced Hypothermia After High-Energy Soft-Tissue Injury and Subsequent Hemorrhagic Shock , 2002, Shock.

[58]  J. Holcomb,et al.  Intravenous rFVIIa administered for hemorrhage control in hypothermic coagulopathic swine with grade V liver injuries. , 2001, The Journal of trauma.

[59]  B Brismar,et al.  Acute hemodynamic effects of induced hypothermia in hemorrhagic shock: an experimental study in the pig. , 2001, Shock.

[60]  T. Sakamoto,et al.  Surface cooling, which fails to reduce the core temperature rapidly, hastens death during severe hemorrhagic shock in pigs. , 2000, Journal of Trauma.

[61]  H. Tscherne,et al.  Adenosine-triphosphate in trauma-related and elective hypothermia. , 1999, The Journal of trauma.

[62]  J. Holcomb,et al.  Dry fibrin sealant dressings reduce blood loss, resuscitation volume, and improve survival in hypothermic coagulopathic swine with grade V liver injuries. , 1999, The Journal of trauma.

[63]  B. Brismar,et al.  Acute metabolic and endocrine effects of induced hypothermia in hemorrhagic shock: an experimental study in the pig. , 1998, The Journal of trauma.

[64]  H. Redl,et al.  Animal Models as the Basis of Pharmacologic Intervention in Trauma and Sepsis Patients , 1996, World Journal of Surgery.

[65]  D. Sessler,et al.  Mild hypothermia increases blood loss and transfusion requirements during total hip arthroplasty , 1996, The Lancet.

[66]  O. Jonasson,et al.  Incidence and timing of hypothermia in trauma patients undergoing operations. , 1991, The Journal of trauma.

[67]  S. Shackford,et al.  Implications of admission hypothermia in trauma patients. , 1990, The Journal of trauma.

[68]  G. Jurkovich,et al.  Hypothermia in trauma victims: an ominous predictor of survival. , 1987, The Journal of trauma.

[69]  Ronald V. Maier,et al.  Incidence and effect of hypothermia in seriously injured patients. , 1986, The Journal of trauma.