Local overexpression of HB-EGF exacerbates remodeling following myocardial infarction by activating noncardiomyocytes

[1]  Chih-Yang Huang,et al.  Insulin-like growth factor-induced hypertrophy of cultured adult rat cardiomyocytes is L-type calcium-channel-dependent , 2002, Molecular and Cellular Biochemistry.

[2]  M. Eskandarpour,et al.  Combination of angiopoietin-1 and vascular endothelial growth factor gene therapy enhances arteriogenesis in the ischemic myocardium. , 2003, Biochemical and biophysical research communications.

[3]  M. Weitzman,et al.  Direct comparison of efficiency and stability of gene transfer into the mammalian heart using adeno-associated virus versus adenovirus vectors. , 2003, The Journal of thoracic and cardiovascular surgery.

[4]  David C. Lee,et al.  Defective valvulogenesis in HB‐EGF and TACE‐null mice is associated with aberrant BMP signaling , 2003, The EMBO journal.

[5]  H. Mizuguchi,et al.  Postinfarction Treatment With an Adenoviral Vector Expressing Hepatocyte Growth Factor Relieves Chronic Left Ventricular Remodeling and Dysfunction in Mice , 2003, Circulation.

[6]  B. H. Shah,et al.  A central role of EGF receptor transactivation in angiotensin II -induced cardiac hypertrophy. , 2003, Trends in pharmacological sciences.

[7]  E. Su,et al.  Gene therapy vector-mediated expression of insulin-like growth factors protects cardiomyocytes from apoptosis and enhances neovascularization. , 2003, American journal of physiology. Heart and circulatory physiology.

[8]  Masatsugu Hori,et al.  Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[9]  Y. Matsuzawa,et al.  Liver regeneration in heparin-binding EGF-like growth factor transgenic mice after partial hepatectomy. , 2003, Gastroenterology.

[10]  G. Besner,et al.  Upregulation of Endogenous Heparin-Binding EGF-Like Growth Factor (HB-EGF) Expression after Intestinal Ischemia/Reperfusion Injury , 2003, Journal of investigative surgery : the official journal of the Academy of Surgical Research.

[11]  K. Shirouzu,et al.  An optimal therapeutic expression level is crucial for suicide gene therapy for hepatic metastatic cancer in mice , 2003, Hepatology.

[12]  I. Miyamori,et al.  A role of heparin-binding epidermal growth factor-like growth factor in cardiac remodeling after myocardial infarction. , 2002, Biochemical and biophysical research communications.

[13]  T. Aoyama,et al.  Molecular mechanisms of non-apoptosis by Fas stimulation alone versus apoptosis with an additional actinomycin D in cultured cardiomyocytes. , 2002, Cardiovascular research.

[14]  Y. Taniyama,et al.  Angiogenesis and Antifibrotic Action by Hepatocyte Growth Factor in Cardiomyopathy , 2002, Hypertension.

[15]  Takashi Murakami,et al.  Concomitant expression of heparin-binding epidermal growth factor-like growth factor mRNA and basic fibroblast growth factor mRNA in myocardial infarction in rats , 2002, Basic Research in Cardiology.

[16]  C. Basbaum,et al.  Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells , 2002, Nature Medicine.

[17]  Hiroshi Asanuma,et al.  Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy , 2002, Nature Medicine.

[18]  A. Kalmes,et al.  EGFR Transactivation in the Regulation of SMC Function , 2001, Annals of the New York Academy of Sciences.

[19]  G. Besner,et al.  Heparin-binding EGF-like growth factor decreases apoptosis in intestinal epithelial cells in vitro. , 2001, Journal of pediatric surgery.

[20]  E. Mekada,et al.  Immunohistochemical Distribution of CD9, Heparin Binding Epidermal Growth Factor-like Growth Factor, and Integrin α3β1 in Normal Human Tissues , 2001 .

[21]  M. Arai,et al.  Characterization of ultrastructure and its relation with DNA fragmentation in Fas‐induced apoptosis of cultured cardiac myocytes , 2001, The Journal of pathology.

[22]  E. Mekada,et al.  Immunohistochemical distribution of CD9, heparin binding epidermal growth factor-like growth factor, and integrin alpha3beta1 in normal human tissues. , 2001, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[23]  E. Mekada,et al.  Heparin-binding EGF-like growth factor: a juxtacrine growth factor. , 2000, Cytokine & growth factor reviews.

[24]  Y. Matsuzawa,et al.  Ectodomain Shedding of Epidermal Growth Factor Receptor Ligands Is Required for Keratinocyte Migration in Cutaneous Wound Healing , 2000, The Journal of cell biology.

[25]  R. Adam,et al.  Heparin-binding EGF-like growth factor is up-regulated in the obstructed kidney in a cell- and region-specific manner and acts to inhibit apoptosis. , 2000, The American journal of pathology.

[26]  G. Besner,et al.  Heparin-binding epidermal growth factor-like growth factor protects rat intestine from ischemia/reperfusion injury. , 1999, The Journal of surgical research.

[27]  P. Vogt,et al.  Heparin-binding epidermal growth factor-like growth factor, a v-Jun target gene, induces oncogenic transformation. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[28]  A. Ullrich,et al.  EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF , 1999, Nature.

[29]  D. Power,et al.  Heparin-binding EGF-like growth factor mRNA is upregulated in the peri-infarct region of the remnant kidney model: in vitro evidence suggests a regulatory role in myofibroblast transformation. , 1998, Journal of the American Society of Nephrology : JASN.

[30]  G. Takemura,et al.  Role of apoptosis in the disappearance of infiltrated and proliferated interstitial cells after myocardial infarction. , 1998, Circulation research.

[31]  J. Kawabe,et al.  Enhanced expression of heparin-binding EGF-like growth factor and its receptor in hypertrophied left ventricle of spontaneously hypertensive rats. , 1998, Cardiovascular research.

[32]  Q. Li,et al.  Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy. , 1997, The Journal of clinical investigation.

[33]  J. Abraham,et al.  Production of heparin binding epidermal growth factor-like growth factor in the early phase of regeneration after acute renal injury. Isolation and localization of bioactive molecules. , 1997, The Journal of clinical investigation.

[34]  L. Kedes,et al.  Adenovirus-mediated gene transfer into infarcted myocardium: feasibility, timing, and location of expression. , 1996, Journal of molecular and cellular cardiology.

[35]  Arachidonic acid supplementation enhances hydrogen peroxide induced oxidative injury of neonatal rat cardiac myocytes. , 1995, Cardiovascular research.

[36]  X. -. Chen,et al.  Combination gene therapy for liver metastasis of colon carcinoma in vivo. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[37]  S. Yamashita,et al.  Localization of heparin-binding EGF-like growth factor in the smooth muscle cells and macrophages of human atherosclerotic plaques. , 1995, The Journal of clinical investigation.

[38]  Y. Matsuzawa,et al.  Heparin-binding EGF-like growth factor is a potent mitogen for rat hepatocytes. , 1994, Biochemical and biophysical research communications.

[39]  James M. Wilson,et al.  Efficient catheter-mediated gene transfer into the heart using replication-defective adenovirus. , 1994, Gene therapy.

[40]  Noel N Kim,et al.  Identification of Functional Angiotensin II Receptors on Rat Cardiac Fibroblasts , 1993, Circulation.

[41]  S. Nagata,et al.  Lethal effect of the anti-Fas antibody in mice , 1993, Nature.

[42]  M. Klagsbrun,et al.  Heparin-binding EGF-like growth factor stimulation of smooth muscle cell migration: dependence on interactions with cell surface heparan sulfate , 1993, The Journal of cell biology.

[43]  M. Klagsbrun,et al.  Appearance of heparin-binding EGF-like growth factor in wound fluid as a response to injury. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[44]  M. Klagsbrun,et al.  A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF , 1991, Science.

[45]  • Epidermis,et al.  WOUND healing. , 1959, The Medical journal of Australia.