Ex vivo expansion of megakaryocyte progenitors from cryopreserved umbilical cord blood. A potential source of megakaryocytes for transplantation.

[1]  I McNiece,et al.  Ex vivo expansion of hematopoietic progenitor cells and mature cells. , 2001, Experimental hematology.

[2]  I McNiece,et al.  Increased expansion and differentiation of cord blood products using a two-step expansion culture. , 2000, Experimental hematology.

[3]  Y. Kawano,et al.  Low Numbers of Megakaryocyte Progenitors in Grafts of Cord Blood Cells May Result in Delayed Platelet Recovery After Cord Blood Cell Transplant , 2000, Stem cells.

[4]  J. Schenker,et al.  Human umbilical cord blood banking and transplantation: a state of the art. , 2000, European journal of obstetrics, gynecology, and reproductive biology.

[5]  J. Critser,et al.  Cutting Edge Communication: Osmometric and Permeability Characteristics of Human Placental/Umbilical Cord Blood CD34T+ Cells and Their Application to Cryopreservation , 2000 .

[6]  D. English.  Editorial: Freezing Hematopoietic Stem Cells , 2000 .

[7]  Kindred A. Ritchie,et al.  Sustained ex vivo expansion of hematopoietic stem cells mediated by thrombopoietin. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[8]  W. Piacibello,et al.  Engraftment in nonobese diabetic severe combined immunodeficient mice of human CD34(+) cord blood cells after ex vivo expansion: evidence for the amplification and self-renewal of repopulating stem cells. , 1999, Blood.

[9]  H. Hassan,et al.  Cytokine‐Induced Expansion of Human CD34+ Stem/Progenitor and CD34+CD41+ Early Megakaryocytic Marrow Cells Cultured on Normal Osteoblasts , 1999, Stem cells.

[10]  N. Somolinos,et al.  Umbilical cord blood banking for unrelated transplantation: evaluation of cell separation and storage methods. , 1999, Experimental hematology.

[11]  L. Gaudry,et al.  Cord blood is better than bone marrow for generating megakaryocytic progenitor cells. , 1999, Experimental hematology.

[12]  A. Nagler,et al.  Expansion of megakaryocyte progenitors from human umbilical cord blood using a new two‐step separation procedure , 1998, British journal of haematology.

[13]  M. Yamaguchi,et al.  In vitro expansion of CD34+/CD41+ cells from human peripheral blood CD34+/CD41- cells: role of cytokines for in vitro proliferation and differentiation of megakaryocytic progenitors. , 1998, Experimental hematology.

[14]  N. Gorin,et al.  Cell culture bags allow a large extent of ex vivo expansion of LTC-IC and functional mature cells which can subsequently be frozen: interest for large-scale clinical applications , 1998, Bone Marrow Transplantation.

[15]  W. Piacibello,et al.  The role of c‐Mpl ligands in the expansion of cord blood hematopoietic progenitors , 1998, Stem cells.

[16]  M. Koller,et al.  Clinical-scale human umbilical cord blood cell expansion in a novel automated perfusion culture system , 1998, Bone Marrow Transplantation.

[17]  P. Wernet,et al.  The effect of different thawing methods, growth factor combinations and media on the ex vivo expansion of umbilical cord blood primitive and committed progenitors , 1998, Bone Marrow Transplantation.

[18]  Alan K. Smith,et al.  UMBILICAL CORD BLOOD TRANSPLANTS IN ADULTS USING A COMBINATION OF UNEXPANDED AND EX VIVO EXPANDED CELLS: PRELIMINARY CLINICAL OBSERVATIONS , 1998 .

[19]  J. Wagner,et al.  Placental and/or umbilical cord blood: an alternative source of hematopoietic stem cells for transplantation. , 1997, Blood.

[20]  J. Lebkowski,et al.  Animal serum-free culture of purified human CD34+ cells: amplification of progenitors from G-CSF and GM-CSF-mobilized peripheral blood. , 1997, Journal of hematotherapy.

[21]  J Wagner,et al.  Clonogenic capacity andex vivo expansion potential of umbilical cord blood progenitor cells are not impaired by cryopreservation , 1997, Bone Marrow Transplantation.

[22]  P. Pedrazzoli,et al.  Megakaryocytic progenitors can be generated ex vivo and safely administered to autologous peripheral blood progenitor cell transplant recipients. , 1997, Blood.

[23]  W. Piacibello,et al.  Extensive amplification and self-renewal of human primitive hematopoietic stem cells from cord blood. , 1997, Blood.

[24]  I. Mcniece,et al.  Purification of CD34+ cells is essential for optimal ex vivo expansion of umbilical cord blood cells. , 1997, Journal of hematotherapy.

[25]  J. Reiffers,et al.  Expansion of blood CD34+ cells: committed precursor expansion does not affect immature hematopoietic progenitors. , 1997, Journal of hematotherapy.

[26]  G. Sirchia,et al.  Hematopoietic and immune recovery after transplantation of cord blood progenitor cells in children. , 1996, Bone marrow transplantation.

[27]  J. Wagner,et al.  Successful transplantation of HLA-matched and HLA-mismatched umbilical cord blood from unrelated donors: analysis of engraftment and acute graft-versus-host disease. , 1996, Blood.

[28]  J. Kurtzberg,et al.  Placental blood as a source of hematopoietic stem cells for transplantation into unrelated recipients. , 1996, The New England journal of medicine.

[29]  D. Dunlop,et al.  CD34-positive cells isolated from cryopreserved peripheral-blood progenitor cells can be expanded ex vivo and used for transplantation with little or no toxicity. , 1996, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[30]  A. Nagler,et al.  Stem cell factor (SCF) synergizes with megakaryocyte colony stimulating activity in post-irradiated aplastic plasma in stimulating human megakaryocytopoiesis , 1996, Medical oncology.

[31]  Thomas O. Toole,et al.  Hematopoietic potential of cryopreserved and ex vivo manipulated umbilical cord blood progenitor cells evaluated in vitro and in vivo. , 1996, Blood.

[32]  J. Adamson,et al.  Processing and cryopreservation of placental/umbilical cord blood for unrelated bone marrow reconstitution. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[33]  A. Nagler,et al.  The response of cord blood megakaryocyte progenitors to IL‐3, IL‐6 and aplastic canine serum varies with gestational age , 1995, British journal of haematology.

[34]  A. Nagler,et al.  Recombinant Human Interleukin-6 Accelerates In-Virto Megakaryocytopoiesis and Platelet Recovery Post Autologous Peripheral Blood Stem Cell Transplantion , 1995 .

[35]  A. Nagler,et al.  Ex vivo expansion of megakaryocyte precursors by preincubation of marrow allografts with interleukin-3 and granulocyte-macrophage colony-stimulating factor in vitro. , 1995, Experimental hematology.

[36]  A. Nagler,et al.  Human umbilical cord blood for hematopoietic progenitor cells transplantation. , 1995, Leukemia & lymphoma.

[37]  D. Harris,et al.  Collection, separation and cryopreservation of umbilical cord blood for use in transplantation. , 1994, Bone marrow transplantation.

[38]  A. Nagler,et al.  Red blood cell depletion and enrichment of CD34+ hematopoietic progenitor cells from human umbilical cord blood using soybean agglutinin and CD34 immunoselection. , 1994, Experimental hematology.

[39]  A. Eldor,et al.  Circulating megakaryocytes: Delivery of large numbers of intact, mature megakaryocytes to the lungs , 1993, European journal of haematology.

[40]  A. Nagler,et al.  Enhanced marrow recovery by short preincubation of marrow allografts with human recombinant interleukin-3 and granulocyte-macrophage colony-stimulating factor. , 1992, Blood.

[41]  A. Eldor,et al.  Circulating megakaryocytes and platelet production in the lungs. , 1990, Progress in clinical and biological research.