Biological and clinical features of trisomy 21 in adult patients with acute myeloid leukemia.

[1]  J. Crispino,et al.  Myeloid leukemia in Down syndrome. , 2011, Critical reviews in oncogenesis.

[2]  R. Hills,et al.  Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials. , 2010, Blood.

[3]  E. van den Berg,et al.  Cytogenetics of childhood acute myeloid leukemia: United Kingdom Medical Research Council Treatment trials AML 10 and 12. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[4]  Jie Jin,et al.  CD19-positive acute myeloblastic leukemia with trisomy 21 as a sole acquired karyotypic abnormality , 2009, Journal of Zhejiang University SCIENCE B.

[5]  C. Bloomfield,et al.  The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. , 2009, Blood.

[6]  Jie Jin,et al.  Trisomy 21 in patients with acute leukemia , 2009, American journal of hematology.

[7]  Jie Jin,et al.  [Clinical and cytogenetic features of hematologic malignancies associated with acquired trisomy 21]. , 2008, Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics.

[8]  A. C. Chinault,et al.  Syndromic thrombocytopenia and predisposition to acute myelogenous leukemia caused by constitutional microdeletions on chromosome 21q. , 2008, Blood.

[9]  S. Alkindi,et al.  Trisomy 21 as a sole acquired abnormality in an adult Omani patient with CD7- and CD9-positive acute myeloid leukemia. , 2007, Archives of medical research.

[10]  A. Olshan,et al.  Epidemiology of leukemia in children with Down syndrome , 2005, Pediatric blood & cancer.

[11]  B. Emmerich,et al.  Trisomy 21 as the sole clonal aberration in a patient with acute myelomonocytic leukemia with abnormal bone marrow eosinophils and extramedullary involvement , 1994, Annals of Hematology.

[12]  I. Bar-Am,et al.  Classical and molecular cytogenetic abnormalities and outcome of childhood acute myeloid leukaemia: report from a referral centre in Israel , 2004, British journal of haematology.

[13]  N. Casadevall,et al.  Isodicentric/pseudoisodicentric chromosome 21 amplification in four cases of acute myelocytic leukemia or myelodysplasia. , 2002, Cancer genetics and cytogenetics.

[14]  C. Bloomfield,et al.  Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461). , 2002, Blood.

[15]  Katsuya Yamamoto,et al.  A new case of CD7-positive acute myeloblastic leukemia with trisomy 21 as a sole acquired abnormality. , 2002, Cancer genetics and cytogenetics.

[16]  F. Solé,et al.  Pentasomy 21 with two isochromosomes 21 in a case of acute myeloid leukemia without maturation. , 2002, Cancer genetics and cytogenetics.

[17]  M. L. Beau,et al.  Prognostic variables in newly diagnosed children and adolescents with acute myeloid leukemia: Children's Cancer Group Study 213 , 2002, Leukemia.

[18]  D. Grimwade,et al.  The predictive value of hierarchical cytogenetic classification in older adults with acute myeloid leukemia (AML): analysis of 1065 patients entered into the United Kingdom Medical Research Council AML11 trial. , 2001, Blood.

[19]  H. Kondo,et al.  Trisomy 21 as the sole acquired karyotypic abnormality in an adult patient with CD7-positive acute myeloid leukemia. , 2001, Cancer genetics and cytogenetics.

[20]  B. Lange.  The Management of Neoplastic Disorders of Haematopoeisis in Children with Down's Syndrome , 2000, British journal of haematology.

[21]  R. Berger,et al.  Acute megakaryocytic leukaemia with acquired polysomy 21 and translocation t(1;21). , 2000, Annales de genetique.

[22]  B. Johansson,et al.  Cytogenetic findings in a population‐based series of 787 childhood acute lymphoblastic leukemias from the Nordic countries , 2000, European journal of haematology.

[23]  M. Slovak,et al.  Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group/Eastern Cooperative Oncology Group Study. , 2000, Blood.

[24]  F. Behm,et al.  Chromosomal abnormalities in 478 children with acute myeloid leukemia: clinical characteristics and treatment outcome in a cooperative pediatric oncology group study-POG 8821. , 1999, Blood.

[25]  L. Chan,et al.  Trisomy 21 as the sole acquired karyotypic abnormality in acute myeloid leukemia and myelodysplastic syndrome. , 1999, Leukemia research.

[26]  Wan Ariffin Bin Abdullah,et al.  Med Pediatr Oncol , 1999 .

[27]  K Wheatley,et al.  The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties. , 1998, Blood.

[28]  J. Buckley,et al.  Distinctive demography, biology, and outcome of acute myeloid leukemia and myelodysplastic syndrome in children with Down syndrome: Children's Cancer Group Studies 2861 and 2891. , 1998, Blood.

[29]  F. Solé,et al.  A new case of trisomy 21 in a patient with an acute nonlymphocytic leukemia (M5b) , 1997, Cancer genetics and cytogenetics.

[30]  J. Gurney,et al.  Enhanced metabolism of 1-beta-D-arabinofuranosylcytosine in Down syndrome cells: a contributing factor to the superior event free survival of Down syndrome children with acute myeloid leukemia. , 1996, Blood.

[31]  C. Tzeng,et al.  Trisomy 21 in acute myeloid leukemia. , 1996, Cancer genetics and cytogenetics.

[32]  J. Korenberg,et al.  Cytogenetic and molecular analysis of a ring (21) in a patient with partial trisomy 21 and megakaryocytic leukemia. , 1994, American journal of medical genetics.

[33]  J. Rowley,et al.  Clinical and prognostic significance of chromosomal abnormalities in childhood acute myeloid leukemia de novo. , 1995, Leukemia.

[34]  E. Estey,et al.  Clinical and prognostic significance of trisomy 21 in adult patients with acute myelogenous leukemia and myelodysplastic syndromes. , 1995, Leukemia.

[35]  F. Mitelman,et al.  Trisomy 21 in neoplastic cells. , 2005, American journal of medical genetics. Supplement.

[36]  G. Dewald,et al.  Hematologic disorders in 13 patients with acquired trisomy 21 and 13 individuals with Down syndrome. , 2005, American journal of medical genetics. Supplement.

[37]  T. Vietti,et al.  Trisomy 21 in bone marrow cells of a patient with a prolonged preleukemic phase. , 1980, Medical and pediatric oncology.

[38]  Iscn.  International System for Human Cytogenetic Nomenclature , 1978 .

[39]  P. Nilsson,et al.  Non‐random chromosome changes in acute myeloid leukemia. Chromosome banding examination of 30 cases at diagnosis , 1976, International journal of cancer.