Identification of pleiotropic key-regulatory genes related to economically relevant traits in beef cattle through systems biology approach

University of Guelph, Department of Animal Biosciences, Centre for Genetic Improvement of Livestock, Guelph, Ontario, N1G2W1, Canada. 2 Universidade Federal de Minas Gerais, Departamento de Biologia Geral, Belo Horizonte, Minas Gerais, 31270-901, Brazil. CSIRO Livestock Industries, Queensland Bioscience Precinct, 306 Carmody Road, Brisbane, Queensland 4067, Australia Univeristy of California-Davis, Department of Animal Science, Davis, CA, 95616, USA The University of Queensland, School of Chemistry and Molecular Biosciences, Brisbane, Qld 4072, Australia. Universitat Autònoma de Barcelona, Departament de Ciència Animal i dels Aliments, 08193, Barcelona, Spain.Colorado State University, Department of Animal Science, Fort-Colins, CO, 80521, USA pfonseca@uoguelph.ca (Corresponding author)

[1]  D. A. Andrade de Oliveira,et al.  Bovine thyroglobulin gene polymorphisms and their association with sexual precocity in Guzerat bulls , 2017, Reproduction in domestic animals = Zuchthygiene.

[2]  I Misztal,et al.  Genomic analysis of cow mortality and milk production using a threshold-linear model. , 2017, Journal of dairy science.

[3]  A. Reverter,et al.  Global differential gene expression in the pituitary gland and the ovaries of pre- and postpubertal Brahman heifers. , 2017, Journal of animal science.

[4]  Y. Ramayo-Caldas,et al.  Multi-breed and multi-trait co-association analysis of meat tenderness and other meat quality traits in three French beef cattle breeds , 2016, Genetics Selection Evolution.

[5]  S. McWilliam,et al.  Non-synonymous mutations mapped to chromosome X associated with andrological and growth traits in beef cattle , 2015, BMC Genomics.

[6]  Jun Ren,et al.  RBM20 is an essential factor for thyroid hormone-regulated titin isoform transition. , 2015, Journal of molecular cell biology.

[7]  N. Dilorenzo,et al.  Effects of anti-phospholipase A(2) antibody supplementation on dry matter intake feed efficiency, acute phase response, and blood differentials of steers fed forage- and grain-based diets. , 2015, Journal of animal science.

[8]  A. Reverter,et al.  Multi-Tissue Omics Analyses Reveal Molecular Regulatory Networks for Puberty in Composite Beef Cattle , 2014, PloS one.

[9]  M. Goddard,et al.  A Multi-Trait, Meta-analysis for Detecting Pleiotropic Polymorphisms for Stature, Fatness and Reproduction in Beef Cattle , 2014, PLoS genetics.

[10]  E. Park,et al.  Thyroid hormone status regulates the expression of secretory phospholipases. , 2014, Biochemical and biophysical research communications.

[11]  G Fordyce,et al.  Genome-wide association studies of female reproduction in tropically adapted beef cattle. , 2012, Journal of animal science.

[12]  Y. Shoenfeld,et al.  Pathogenesis of infertility and recurrent pregnancy loss in thyroid autoimmunity. , 2012, Journal of autoimmunity.

[13]  P. Ellinor,et al.  RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing , 2012, Nature Medicine.

[14]  F. Biro,et al.  Puberty and Its Measurement: A Decade in Review , 2011 .

[15]  M. Beckmann,et al.  Thyroid hormone receptors and reproduction. , 2010, Journal of reproductive immunology.

[16]  T. Visser,et al.  Genetics and phenomics of hypothyroidism and goiter due to iodotyrosine deiodinase (DEHAL1) gene mutations , 2010, Molecular and Cellular Endocrinology.

[17]  G. Donofrio,et al.  Defining Postpartum Uterine Disease and the Mechanisms of Infection and Immunity in the Female Reproductive Tract in Cattle1 , 2009, Biology of reproduction.

[18]  T Centner,et al.  Differential expression of cardiac titin isoforms and modulation of cellular stiffness. , 2000, Circulation research.