Gene vaccination: plasmid DNA is more than just a blueprint.
暂无分享,去创建一个
E. Raz | M. Roman | M. Corr | M Corr | H. Tighe | H Tighe | M Roman | E Raz | Helen Tighe | Eyal Raz
[1] Y. Barenholz,et al. Exogenous hepatitis B surface antigen particles processed by dendritic cells or macrophages prime murine MHC class I-restricted cytotoxic T lymphocytes in vivo. , 1995, Journal of immunology.
[2] M. Bennett,et al. Therapeutic effect of DNA immunization of genetically susceptible mice infected with virulent Mycoplasma pulmonis. , 1997, Journal of immunology.
[3] M. Provinciali,et al. Autoantibody to p185erbB2/neu oncoprotein by vaccination with xenogenic DNA , 1997, Cancer Immunology, Immunotherapy.
[4] C. Snapper,et al. Regulation by interferon alpha of immunoglobulin isotype selection and lymphokine production in mice , 1991, The Journal of experimental medicine.
[5] D. Doolan,et al. Nucleic Acid Malaria Vaccines , 1995 .
[6] J. Wands,et al. Enhancement of cellular and humoral immune responses to hepatitis C virus core protein using DNA-based vaccines augmented with cytokine-expressing plasmids. , 1997, Journal of immunology.
[7] G. Bishop,et al. CpG motifs in bacterial DNA trigger direct B-cell activation , 1995, Nature.
[8] E. Kuramoto,et al. In vitro Augmentation of Natural Killer Cell Activity and Production of Interferon‐α/β and ‐γ with Deoxyribonucleic Acid Fraction from Mycobacterium bovis BCG , 1988, Japanese journal of cancer research : Gann.
[9] R A Houghten,et al. Induction of neonatal tolerance by plasmid DNA vaccination of mice. , 1996, The Journal of clinical investigation.
[10] E. Kuramoto,et al. Antitumor Activity of Synthetic Oligonucleotides with Sequences from cDNA Encoding Proteins of Mycobacterium bovis BCG , 1992, Japanese journal of cancer research : Gann.
[11] H. Davis,et al. DNA-mediated immunization to hepatitis B surface antigen: longevity of primary response and effect of boost. , 1996, Vaccine.
[12] J. Monaco,et al. The genetics of proteasomes and antigen processing. , 1995, Annual review of genetics.
[13] J. Reimann,et al. DNA vaccination primes MHC class I-restricted, simian virus 40 large tumor antigen-specific CTL in H-2d mice that reject syngeneic tumors. , 1996, Journal of immunology.
[14] R. Webster,et al. Protection of ferrets against influenza challenge with a DNA vaccine to the haemagglutinin. , 1994, Vaccine.
[15] D. Pisetsky. Immune activation by bacterial DNA: a new genetic code. , 1996, Immunity.
[16] I. Cohen,et al. Suppressive vaccination with DNA encoding a variable region gene of the T–cell receptor prevents autoimmune encephalomyelitis and activates Th2 immunity , 1996, Nature Medicine.
[17] E. Kuramoto,et al. Synthetic Oligonucleotides with Particular Base Sequences from the cDNA Encoding Proteins of Mycobacterium bovis BCG Induce Interferons and Activate Natural Killer Cells , 1992, Microbiology and immunology.
[18] H. Ploegh,et al. Intracellular transport of MHC class II molecules. , 1992, Immunology today.
[19] M. Kovacsovics-Bankowski,et al. A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules , 1995, Science.
[20] R. Hohlfeld,et al. The immunobiology of muscle. , 1994, Immunology today.
[21] K. Heeg,et al. Sensitization of MHC class I-restricted T cells to exogenous proteins: evidence for an alternative class I-restricted antigen presentation pathway. , 1995, Immunology.
[22] H. Okamura,et al. Cloning of a new cytokine that induces IFN-γ production by T cells , 1995, Nature.
[23] G. Trinchieri. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. , 1995, Annual review of immunology.
[24] D. Pisetsky,et al. Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA. , 1991, Journal of immunology.
[25] J. Fechner,et al. Immunity to MHC class I antigen after direct DNA transfer into skeletal muscle. , 1994, Journal of immunology.
[26] J. Ulmer,et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. , 1993, Science.
[27] C. Harding,et al. Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class I MHC molecules. , 1994, Journal of immunology.
[28] Donna L. Montgomery,et al. Immunogenicity and protective efficacy of a tuberculosis DNA vaccine , 1996, Nature Medicine.
[29] HL Davis,et al. Immune-mediated destruction of transfected muscle fibers after direct gene transfer with antigen-expressing plasmid DNA , 1997, Gene Therapy.
[30] M. Yokoyama,et al. DNA immunization confers protection against lethal lymphocytic choriomeningitis virus infection , 1995, Journal of virology.
[31] J. Ulmer,et al. Generation of MHC class I‐restricted cytotoxic T lymphocytes by expression of a viral protein in muscle cells: antigen presentation by non‐muscle cells , 1996, Immunology.
[32] A. Krieg,et al. Bacterial DNA induces NK cells to produce IFN-gamma in vivo and increases the toxicity of lipopolysaccharides. , 1996, Journal of immunology.
[33] Y. Fujisawa,et al. Antitumor activity of deoxyribonucleic acid fraction from Mycobacterium bovis BCG. I. Isolation, physicochemical characterization, and antitumor activity. , 1984, Journal of the National Cancer Institute.
[34] A. Bird. CpG-rich islands and the function of DNA methylation , 1986, Nature.
[35] G. Acsadi,et al. Long-term persistence of plasmid DNA and foreign gene expression in mouse muscle. , 1992, Human molecular genetics.
[36] H. Davis,et al. DNA-based immunization induces continuous secretion of hepatitis B surface antigen and high levels of circulating antibody. , 1993, Human molecular genetics.
[37] D. Pisetsky,et al. Bacterial DNA Induces Murine Interferon-γ Production by Stimulation of Interleukin-12 and Tumor Necrosis Factor-α , 1996 .
[38] Simon C Watkins,et al. DNA–based immunization by in vivo transfection of dendritic cells , 1996, Nature Medicine.
[39] T. Mosmann,et al. Functional diversity of T lymphocytes due to secretion of different cytokine patterns , 1991, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[40] D. Richman,et al. Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants , 1997, Nature Medicine.
[41] L. Babiuk,et al. Bovine herpesvirus 1: immune responses in mice and cattle injected with plasmid DNA , 1993, Journal of virology.
[42] D. Weiner,et al. Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination , 1997, Nature Medicine.
[43] D. Pisetsky. DNA and the Immune System , 1997, Annals of Internal Medicine.
[44] F. Liew,et al. Protection against leishmaniasis by injection of DNA encoding a major surface glycoprotein, gp63, of L. major. , 1995, Immunology.
[45] J. Reimann,et al. Targeting an anti-viral CD8+ T cell response to a growing tumor facilitates its rejection , 1997, Cancer Immunology, Immunotherapy.
[46] R. Germain,et al. Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosis , 1995, The Journal of experimental medicine.
[47] M. Croft,et al. A direct role for IFN-gamma in regulation of Th1 cell development. , 1996, Journal of immunology.
[48] J. Shiver,et al. Heterologous and homologous protection against influenza A by DNA vaccination: optimization of DNA vectors. , 1993, DNA and cell biology.
[49] R. Schwartz,et al. Antigen presentation by chemically modified splenocytes induces antigen- specific T cell unresponsiveness in vitro and in vivo , 1987, The Journal of experimental medicine.
[50] A. Sing,et al. Interferon beta, a cofactor in the interferon gamma production induced by gram-negative bacteria in mice , 1995, The Journal of experimental medicine.
[51] D. Carson,et al. Costimulation provided by DNA immunization enhances antitumor immunity. , 1997, Journal of immunology.
[52] H. Fujita,et al. Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin , 1983, The Journal of experimental medicine.
[53] B. Rouse,et al. Genetic immunization against herpes simplex virus. Protection is mediated by CD4+ T lymphocytes. , 1995, Journal of immunology.
[54] Z. Xiang,et al. Vaccination with a plasmid vector carrying the rabies virus glycoprotein gene induces protective immunity against rabies virus. , 1994, Virology.
[55] C. Heusser,et al. Interferon alpha increases the frequency of interferon gamma-producing human CD4+ T cells , 1993, The Journal of experimental medicine.
[56] R. Steinman,et al. The dendritic cell system and its role in immunogenicity. , 1991, Annual review of immunology.
[57] R. Schwartz. Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy , 1992, Cell.
[58] D. Klinman,et al. Contribution of CpG motifs to the immunogenicity of DNA vaccines. , 1997, Journal of immunology.
[59] C. Leclerc,et al. DNA‐Mediated Immunization to the Hepatitis B Surface Antigen , 1995, Annals of the New York Academy of Sciences.
[60] M. Colston,et al. Vaccination against tuberculosis by DNA injection , 1996, Nature Medicine.
[61] R. Webster,et al. Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization. , 1997, Journal of immunology.
[62] K. Rock,et al. Presentation of exogenous antigens by macrophages: analysis of major histocompatibility complex class I and II presentation and regulation by cytokines , 1994, European journal of immunology.
[63] J. Reimann,et al. DNA-mediated immunization in mice induces a potent MHC class I-restricted cytotoxic T lymphocyte response to the hepatitis B envelope protein. , 1995, Human gene therapy.
[64] R. Schwartz,et al. Stimulation of normal inducer T cell clones with antigen presented by purified Ia molecules in planar lipid membranes: specific induction of a long-lived state of proliferative nonresponsiveness. , 1987, Journal of immunology.
[65] R. Coffman,et al. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. , 1989, Annual review of immunology.
[66] B. Rouse,et al. DNA immunization of neonates induces immunity despite the presence of maternal antibody. , 1997, The Journal of clinical investigation.
[67] B. Rouse,et al. Induction of protective immunity against herpes simplex virus with DNA encoding the immediate early protein ICP 27. , 1995, Viral immunology.
[68] M. de Carli,et al. IL-4 and IFN (alpha and gamma) exert opposite regulatory effects on the development of cytolytic potential by Th1 or Th2 human T cell clones. , 1992, Journal of immunology.
[69] E. Kuramoto,et al. Unique palindromic sequences in synthetic oligonucleotides are required to induce IFN [correction of INF] and augment IFN-mediated [correction of INF] natural killer activity. , 1992, Journal of immunology.
[70] P. Srivastava,et al. A mechanism for the specific immunogenicity of heat shock protein-chaperoned peptides. , 1995, Science.
[71] R. Welsh,et al. Protective CTL-dependent immunity and enhanced immunopathology in mice immunized by particle bombardment with DNA encoding an internal virion protein. , 1995, Journal of immunology.
[72] D. Tang,et al. Genetic immunization is a simple method for eliciting an immune response , 1992, Nature.
[73] H. Ploegh,et al. Generation, translocation, and presentation of MHC class I-restricted peptides. , 1995, Annual review of biochemistry.
[74] R. Levy,et al. DNA immunization induces protective immunity against B–cell lymphoma , 1996, Nature Medicine.
[75] C. Hsieh,et al. Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. , 1993, Science.
[76] E. Raz,et al. Immunostimulatory DNA Sequences Necessary for Effective Intradermal Gene Immunization , 1996, Science.
[77] J. Shiver,et al. Cytotoxic T Lymphocyte and Helper T Cell Responses following HIV Polynucleotide Vaccination , 1995, Annals of the New York Academy of Sciences.
[78] Z. Xiang,et al. Manipulation of the immune response to a plasmid-encoded viral antigen by coinoculation with plasmids expressing cytokines. , 1995, Immunity.
[79] Z. Xiang,et al. Immune response to neonatal genetic immunization. , 1997, Virology.
[80] R. Schwartz,et al. Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy. , 1989, Annual review of immunology.
[81] D. Lancki,et al. Differential regulation of murine T lymphocyte subsets. , 1993, Annual review of immunology.
[82] D. Pardoll,et al. In vivo cross-priming of MHC class I-restricted antigens requires the TAP transporter. , 1996, Immunity.
[83] A. García-Sastre,et al. DNA immunization of newborn mice with a plasmid-expressing nucleoprotein of influenza virus. , 1996, Viral immunology.
[84] F. Annunziato,et al. Polyinosinic acid: polycytidylic acid promotes T helper type 1‐specific immune responses by stimulating macrophage production of interferon‐α and interleukin‐12 , 1995, European journal of immunology.
[85] E. Kuramoto,et al. DNA from Bacteria, but Not from Vertebrates, Induces Interferons, Activates Natural Killer Cells and Inhibits Tumor Growth , 1992, Microbiology and immunology.
[86] D. Fuller,et al. A qualitative progression in HIV type 1 glycoprotein 120-specific cytotoxic cellular and humoral immune responses in mice receiving a DNA-based glycoprotein 120 vaccine. , 1994, AIDS research and human retroviruses.
[87] T. Mosmann,et al. The expanding universe of T-cell subsets: Th1, Th2 and more. , 1996, Immunology today.
[88] R. Webster,et al. Use of DNA encoding influenza hemagglutinin as an avian influenza vaccine. , 1993, DNA and cell biology.
[89] H. Yamamoto,et al. Antitumor activity of the DNA fraction from Mycobacterium bovis BCG. II. Effects on various syngeneic mouse tumors. , 1985, Journal of the National Cancer Institute.
[90] W. W. Nichols,et al. Potential DNA Vaccine Integration into Host Cell Genome , 1995, Annals of the New York Academy of Sciences.
[91] J. Ulmer,et al. Protective Efficacy of Intramuscular Immunization with Naked DNA , 1995, Annals of the New York Academy of Sciences.
[92] T. Tokunaga,et al. In vivo augmentation of natural killer cell activity with a deoxyribonucleic acid fraction of BCG. , 1986, Japanese journal of cancer research : Gann.
[93] Shau-ku Huang,et al. Immunoprophylaxis of allergen–induced immunoglobulin E synthesis and airway hyperresponsiveness in vivo by genetic immunization , 1996, Nature Medicine.
[94] J. Drazen,et al. Sorting out the cytokines of asthma , 1996, The Journal of experimental medicine.
[95] K. Rock,et al. Antigen processing and presentation by the class I major histocompatibility complex. , 1996, Annual review of immunology.
[96] V. Srikantan,et al. DNA inoculation induces neutralizing immune responses against human immunodeficiency virus type 1 in mice and nonhuman primates. , 1993, DNA and cell biology.