Amyloidosis cutis dyschromica: four cases from two families

Amyloidosis cutis dyschromica is a rare distinct type of primary cutaneous amyloidosis, as most of the literatures on such topic have been written in Japanese; dermatologists outside of Japan are not familiar with this condition. We herein present a report of four patients from two families, three males and one female. The mean age at onset was 9 years old. In this paper, the literature was reviewed and the unique clinical, histological, and genetic features of this condition are delineated.