Digital Signaling and Hysteresis Characterize Ras Activation in Lymphoid Cells
暂无分享,去创建一个
Jayajit Das | Arup K. Chakraborty | Arthur Weiss | A. Chakraborty | A. Weiss | C. Govern | J. Zikherman | J. Das | Ming Yang | J. Roose | Julie Zikherman | M. Ho | Jeroen P. Roose | Ming Yang | Mary Ho | Christopher Govern
[1] X. Bustelo,et al. RasGRF2, a Guanosine Nucleotide Exchange Factor for Ras GTPases, Participates in T-Cell Signaling Responses , 2007, Molecular and Cellular Biology.
[2] A. Weiss,et al. Unusual Interplay of Two Types of Ras Activators, RasGRP and SOS, Establishes Sensitive and Robust Ras Activation in Lymphocytes , 2007, Molecular and Cellular Biology.
[3] N. Kampen,et al. Stochastic processes in physics and chemistry , 1981 .
[4] Eduardo Sontag,et al. Untangling the wires: A strategy to trace functional interactions in signaling and gene networks , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[5] Philippe Bousso,et al. Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes , 2003, Nature Immunology.
[6] Andreas Wagner,et al. Faculty Opinions recommendation of Bacterial persistence: a model of survival in changing environments. , 2005 .
[7] J. Elf,et al. Spontaneous separation of bi-stable biochemical systems into spatial domains of opposite phases. , 2004, Systems biology.
[8] Tianhai Tian,et al. Plasma membrane nanoswitches generate high-fidelity Ras signal transduction , 2007, Nature Cell Biology.
[9] E. Génot,et al. Ras regulation and function in lymphocytes. , 2000, Current opinion in immunology.
[10] Holger Sondermann,et al. Regulation of Ras Signaling Dynamics by Sos-Mediated Positive Feedback , 2006, Current Biology.
[11] Jodi Gureasko,et al. Membrane-dependent signal integration by the Ras activator Son of sevenless , 2008, Nature Structural &Molecular Biology.
[12] W. Ebeling. Stochastic Processes in Physics and Chemistry , 1995 .
[13] J. J. Gilbert,et al. Antigen receptors on immature, but not mature, B and T cells are coupled to cytosolic phospholipase A2 activation: expression and activation of cytosolic phospholipase A2 correlate with lymphocyte maturation. , 1996, Journal of immunology.
[14] S. Dower. Cytokines, virokines and the evolution of immunity , 2000, Nature Immunology.
[15] A. Arkin,et al. Stochastic mechanisms in gene expression. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[16] J. Ferrell. Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability. , 2002, Current opinion in cell biology.
[17] A. Wittinghofer,et al. Mutational and kinetic analyses of the GTPase-activating protein (GAP)-p21 interaction: the C-terminal domain of GAP is not sufficient for full activity , 1992, Molecular and cellular biology.
[18] Arthur Weiss,et al. A Diacylglycerol-Protein Kinase C-RasGRP1 Pathway Directs Ras Activation upon Antigen Receptor Stimulation of T Cells , 2005, Molecular and Cellular Biology.
[19] Barbara Hausmann,et al. Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling , 2006, Nature.
[20] P. Blumberg,et al. RasGRP links T-cell receptor signaling to Ras. , 2000, Blood.
[21] Timothy K Starr,et al. Positive and negative selection of T cells. , 2003, Annual review of immunology.
[22] Holger Sondermann,et al. Structural Analysis of Autoinhibition in the Ras Activator Son of Sevenless , 2004, Cell.
[23] A. Chakraborty,et al. T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation , 2008, Nature Immunology.
[24] S. Marqusee,et al. A Ras-induced conformational switch in the Ras activator Son of sevenless , 2006, Proceedings of the National Academy of Sciences.
[25] Alex Braiman,et al. Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1 , 2006, Nature Structural &Molecular Biology.
[26] F. McCormick,et al. A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants. , 1987, Science.
[27] G. G. Stokes. "J." , 1890, The New Yale Book of Quotations.
[28] Channing J Der,et al. Increasing complexity of Ras signaling , 1998, Oncogene.
[29] Andre Hoelz,et al. Structural Evidence for Feedback Activation by Ras·GTP of the Ras-Specific Nucleotide Exchange Factor SOS , 2003, Cell.
[30] D. Sherrington. Stochastic Processes in Physics and Chemistry , 1983 .
[31] A. Chakraborty,et al. Origin of the sharp boundary that discriminates positive and negative selection of thymocytes , 2009, Proceedings of the National Academy of Sciences.
[32] A. Weiss,et al. Ligand-receptor interactions required for commitment to the activation of the interleukin 2 gene. , 1987, Journal of immunology.
[33] D. Bar-Sagi,et al. Regulation of Sos Activity by Intramolecular Interactions , 1998, Molecular and Cellular Biology.
[34] Rajat Varma,et al. Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes , 2007, Nature Immunology.
[35] T. Kurosaki,et al. Requirement for Ras Guanine Nucleotide Releasing Protein 3 in Coupling Phospholipase C-γ2 to Ras in B Cell Receptor Signaling , 2003, The Journal of experimental medicine.
[36] Ronald N Germain,et al. Modeling T Cell Antigen Discrimination Based on Feedback Control of Digital ERK Responses , 2005, PLoS biology.
[37] J. Stone,et al. RasGRP is essential for mouse thymocyte differentiation and TCR signaling , 2000, Nature Immunology.
[38] M. Nussenzweig,et al. Corrigendum: Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes , 2007, Nature Immunology.
[39] D. Bowtell,et al. Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signaling and development. , 1997, Genes & development.
[40] D. Gillespie. Exact Stochastic Simulation of Coupled Chemical Reactions , 1977 .
[41] J. Hartigan,et al. The Dip Test of Unimodality , 1985 .
[42] M. Tyers,et al. Stratus Not Altocumulus: A New View of the Yeast Protein Interaction Network , 2006, PLoS biology.
[43] U. Bhalla,et al. Emergent properties of networks of biological signaling pathways. , 1999, Science.
[44] M. Philips,et al. Compartmentalized Ras/MAPK signaling. , 2006, Annual review of immunology.
[45] A. B. Bortz,et al. A new algorithm for Monte Carlo simulation of Ising spin systems , 1975 .