The protein kinase KSR interacts with 14-3-3 protein and Raf

[1]  G. Rubin,et al.  KSR modulates signal propagation within the MAPK cascade. , 1996, Genes & development.

[2]  P. J. Belshaw,et al.  Oligomerization activates c-Raf-1 through a Ras-dependent mechanism , 1996, Nature.

[3]  M. Farrar,et al.  Activation of the Raf-1 kinase cascade by coumermycin-induced dimerization , 1996, Nature.

[4]  A. Aitken 14-3-3 and its possible role in co-ordinating multiple signalling pathways. , 1996, Trends in cell biology.

[5]  P. Allen,et al.  Interaction of 14-3-3 with Signaling Proteins Is Mediated by the Recognition of Phosphoserine , 1996, Cell.

[6]  Henry C. Chang,et al.  KSR, a novel protein kinase required for RAS signal transduction , 1995, Cell.

[7]  H. Horvitz,et al.  The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans , 1995, Cell.

[8]  Min Han,et al.  The C. elegans ksr-1 gene encodes a novel raf-related kinase involved in Ras-mediated signal transduction , 1995, Cell.

[9]  R. Kolesnick,et al.  Phosphorylation of Raf by ceramide-activated protein kinase , 1995, Nature.

[10]  F. McCormick,et al.  Bcr and Raf form a complex in vivo via 14‐3‐3 proteins. , 1995, The EMBO journal.

[11]  D. Morrison,et al.  Reversal of Raf-1 activation by purified and membrane-associated protein phosphatases. , 1995, Science.

[12]  D. Morrison,et al.  14-3-3 is not essential for Raf-1 function: identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent manner , 1995, Molecular and cellular biology.

[13]  W. Kolch,et al.  Regulation of Raf‐1 kinase activity by the 14‐3‐3 family of proteins. , 1995, The EMBO journal.

[14]  G M Bokoch,et al.  Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins. , 1994, The Journal of biological chemistry.

[15]  W. Fantl,et al.  Activation of Raf-1 by 14-3-3 proteins , 1994, Nature.

[16]  K. Irie,et al.  Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinase. , 1994, Science.

[17]  F. McCormick,et al.  Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation. , 1994, Science.

[18]  E. Elion,et al.  Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae , 1994, Cell.

[19]  J. Hancock,et al.  Activation of Raf as a result of recruitment to the plasma membrane. , 1994, Science.

[20]  Sally J. Leevers,et al.  Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane , 1994, Nature.

[21]  R. Jove,et al.  Raf exists in a native heterocomplex with hsp90 and p50 that can be reconstituted in a cell-free system. , 1993, The Journal of biological chemistry.

[22]  D. Morrison,et al.  Identification of the major phosphorylation sites of the Raf-1 kinase. , 1993, The Journal of biological chemistry.

[23]  D. Morrison,et al.  Requirement for Raf and MAP kinase function during the meiotic maturation of Xenopus oocytes , 1993, The Journal of cell biology.

[24]  Anthony J. Muslin,et al.  Raf-1 protein kinase is important for progesterone-induced Xenopus oocyte maturation and acts downstream of mos , 1993, Molecular and cellular biology.

[25]  Jeffrey L. Wrana,et al.  TGFβ signals through a heteromeric protein kinase receptor complex , 1992, Cell.

[26]  T. M. Roberts A signal chain of events , 1992, Nature.

[27]  L. J. Korn,et al.  Ras p21 as a potential mediator of insulin action in Xenopus oocytes. , 1987, Science.

[28]  W. Kolch,et al.  Protein kinase C alpha activates RAF-1 by direct phosphorylation. , 1993, Nature.