Adaptive Noise Reduction in Microarray Images Based on the Center-Weighted Vector Medians

In this paper, we provide a new noise reduction method for the enhancement of the images of gene chips. We demonstrate that the new technique is capable of reducing outliers present in microarray images while preserving the spot edges. This paper contains the comparisons of the proposed technique with the standard schemes used in color image filtering, as well as examples of their efficiency when these methods are applied to typical microarray images.