Effects of ethanol extract of Azadirachta indica leaves on some immunological and haematological parameters of diabetic Wistar rats.

(Family: Meliaceae) leaves on immunological and haematological parameters of alloxan-induced diabetic rats were investigated with a view to ascertaining its involvement in the immunological or inflammatory control of diabetic vascular complications. Total white blood cell, red blood cell, total lymphocyte and neutrophil counts were determined by microscopy. CD

[1]  G. Hansson.  Inflammation, atherosclerosis, and coronary artery disease. , 2005, The New England journal of medicine.

[2]  T. V. van Berkel,et al.  Blocking endothelial adhesion molecules: a potential therapeutic strategy to combat atherogenesis , 2004, Current opinion in lipidology.

[3]  E. Shu,et al.  An antimalarial extract from neem leaves is antiretroviral. , 2004, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[4]  M. Athar,et al.  Nimbidin suppresses functions of macrophages and neutrophils: relevance to its antiinflammatory mechanisms , 2004, Phytotherapy research : PTR.

[5]  P. Gupta,et al.  Protective role of extracts of neem seeds in diabetes caused by streptozotocin in rats. , 2004, Journal of ethnopharmacology.

[6]  P. Arner.  The adipocyte in insulin resistance: key molecules and the impact of the thiazolidinediones , 2003, Trends in Endocrinology & Metabolism.

[7]  I. Charo,et al.  Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherogenesis. , 2003, The Journal of clinical investigation.

[8]  S. Yanpallewar,et al.  Effect of Azadirachta indica on paracetamol-induced hepatic damage in albino rats. , 2003, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[9]  Eshrat M. Halim.  Lowering of blood sugar by water extract of Azadirachta indica and Abroma augusta in diabetes rats. , 2003, Indian journal of experimental biology.

[10]  Qingbo Xu.  Role of heat shock proteins in atherosclerosis. , 2002, Arteriosclerosis, thrombosis, and vascular biology.

[11]  U. Bandyopadhyay,et al.  Biological activities and medicinal properties of neem (Azadirachta indica) , 2002 .

[12]  M. Brownlee.  Biochemistry and molecular cell biology of diabetic complications , 2001, Nature.

[13]  L. Lindbom,et al.  Importance of Primary Capture and L-Selectin–Dependent Secondary Capture in Leukocyte Accumulation in Inflammation and Atherosclerosis in Vivo , 2001, The Journal of experimental medicine.

[14]  S. Haffner,et al.  Insulin-resistant prediabetic subjects have more atherogenic risk factors than insulin-sensitive prediabetic subjects: implications for preventing coronary heart disease during the prediabetic state. , 2000, Circulation.

[15]  P. Khosla,et al.  A study of hypoglycaemic effects of Azadirachta indica (Neem) in normaland alloxan diabetic rabbits. , 2000, Indian journal of physiology and pharmacology.

[16]  I. Charo,et al.  Decreased lesion formation in CCR2−/− mice reveals a role for chemokines in the initiation of atherosclerosis , 1998, Nature.

[17]  Rachel J. Wilson,et al.  1997 revised guidelines for performing CD4+ T-cell determinations in persons infected with human immunodeficiency virus (HIV). Centers for Disease Control and Prevention. , 1997, MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports.

[18]  T. Paavonen,et al.  Infiltrates of activated mast cells at the site of coronary atheromatous erosion or rupture in myocardial infarction. , 1995, Circulation.

[19]  J. Witztum,et al.  T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[20]  M. Cybulsky,et al.  Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. , 1991, Science.

[21]  G. Hansson,et al.  Immune mechanisms in atherosclerosis. , 1989, Arteriosclerosis.

[22]  M. P. Cohen.  Diabetes and Protein Glycosylation. Measurement and Biologic Relevance , 1986 .

[23]  V. Dixit,et al.  Effect of Neem seed oil on the blood glucose concentration of normal and alloxan diabetic rats. , 1986, Journal of ethnopharmacology.

[24]  G. Bondjers,et al.  Regional Accumulations of T Cells, Macrophages, and Smooth Muscle Cells in the Human Atherosclerotic Plaque , 1986, Arteriosclerosis.

[25]  A. Cerami.  Hypothesis. Glucose as a mediator of aging. , 1985, Journal of the American Geriatrics Society.