Summary of the OECD’s New Guidance Document on the Recognition, Assessment, and Use of Clinical Signs as Humane Endpoints for Experimental Animals Used in Safety Evaluation

[1]  J. Wallace Humane endpoints and cancer research. , 2000, ILAR journal.

[2]  T. Jeneskog,et al.  Pain and distress in laboratory rodents and lagomorphs: Report of the Federation of European Laboratory Animal Science Associations (FELASA) Working Group on Pain and Distress accepted by the FELASA Board of Management November 1992 , 1994, Laboratory animals.

[3]  L. Toth The moribund state as an experimental endpoint. , 1997, Contemporary topics in laboratory animal science.

[4]  E. Olfert,et al.  Guide to the care and use of experimental animals , 1993 .

[5]  C. C. Lee,et al.  Screening procedures for eye irritation. , 1993, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[6]  C. Hendriksen,et al.  Refinement of vaccine potency testing with the use of humane endpoints. , 2000, ILAR journal.

[7]  D. Morton,et al.  A systematic approach for establishing humane endpoints. , 2000, ILAR journal.

[8]  E. Carstens,et al.  Recognizing pain and distress in laboratory animals. , 2000, ILAR journal.

[9]  W. Morgan Guidelines for the recognition and assessment of pain in animals. Prepared by a working party of the Association of Veterinary Teachers and Research Workers. , 1990, The Veterinary record.

[10]  P. Flecknell,et al.  Recommendations for euthanasia of experimental animals: Part 1 , 1996, Laboratory animals.

[11]  N Sass,et al.  Humane endpoints and acute toxicity testing. , 2000, ILAR journal.

[12]  A. M. Harvey Classification of Chronic Pain—Descriptions of Chronic Pain Syndromes and Definitions of Pain Terms , 1995 .

[13]  W. Russell,et al.  Ethical and Scientific Considerations Regarding Animal Testing and Research , 2011, PloS one.

[14]  E. Olfert,et al.  Humane endpoints for infectious disease animal models. , 2000, ILAR journal.

[15]  E. Saravolac,et al.  Development of a murine hypothermia model for study of respiratory tract influenza virus infection. , 1997, Laboratory animal science.

[16]  H. Smith Humane Endpoints in Animal Experiments for Biomedical Research. , 2000 .

[17]  James C. Murphy,et al.  Ocular irritancy responses to various pHs of acids and bases with and without irrigation. , 1982, Toxicology.

[18]  G N Rao,et al.  Tissue Reaction to an Implantable Identification Device in Mice , 1990, Toxicologic pathology.

[19]  J. Wallace,et al.  The assessment and control of the severity of scientific procedures on laboratory animals , 1990, Laboratory animals.

[20]  S. Charbonneau,et al.  Monitoring animal health during chronic toxicity studies. , 1977, Journal of environmental pathology and toxicology.

[21]  William S. Stokes,et al.  Reducing Unrelieved Pain and Distress in Laboratory Animals Using Humane Endpoints , 2000 .

[22]  M. Dennis Humane endpoints for genetically engineered animal models. , 2000, ILAR journal.

[23]  D. Morton,et al.  The HID50 (hypothermia-inducing dose 50): an alternative to the LD50 for measurement of bacterial virulence. , 1992, International journal of experimental pathology.

[24]  P. Flecknell,et al.  Recommendations for euthanasia of experimental animals: Part 2 , 1997 .

[25]  D. Broom,et al.  Stress and Animal Welfare , 1993, Springer Netherlands.