Novel Morphological Phenotypes Discovery in High-Content Screens Using Underused Features
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Chen Lin | Pengyu Hong | Chris Bakal | Norbert Perrimon | C. Bakal | N. Perrimon | Pengyu Hong | Chen Lin
[1] Anne E Carpenter. Image-based chemical screening. , 2007, Nature chemical biology.
[2] Michael Boutros,et al. Identification of JAK/STAT signalling components by genome-wide RNA interference , 2005, Nature.
[3] Robert F. Murphy,et al. Towards a Systematics for Protein Subcellular Location: Quantitative Description of Protein Localization Patterns and Automated Analysis of Fluorescence Microscope Images , 2000, ISMB.
[4] Hanchuan Peng,et al. Bioimage informatics: a new area of engineering biology , 2008, Bioinform..
[5] Norbert Perrimon,et al. Parallel Chemical Genetic and Genome-Wide RNAi Screens Identify Cytokinesis Inhibitors and Targets , 2004, PLoS biology.
[6] Don H. Johnson,et al. Symmetrizing the Kullback-Leibler Distance , 2001 .
[7] David G. Stork,et al. Pattern Classification (2nd ed.) , 1999 .
[8] Daniel Rauh,et al. An Unbiased Cell Morphology–Based Screen for New, Biologically Active Small Molecules , 2005, PLoS biology.
[9] Bianca Habermann,et al. Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis , 2005, Nature.
[10] Lani F. Wu,et al. Characterizing heterogeneous cellular responses to perturbations , 2008, Proceedings of the National Academy of Sciences.
[11] Cynthia L Adams,et al. Compound classification using image-based cellular phenotypes. , 2006, Methods in enzymology.
[12] C. Bakal,et al. Quantitative Morphological Signatures Define Local Signaling Networks Regulating Cell Morphology , 2007, Science.
[13] Anne E Carpenter,et al. A Novel Small Molecule Regulator of Guanine Nucleotide Exchange Activity of the ADP-ribosylation Factor and Golgi Membrane Trafficking* , 2008, Journal of Biological Chemistry.
[14] R. Saint,et al. A RhoGEF and Rho family GTPase-activating protein complex links the contractile ring to cortical microtubules at the onset of cytokinesis. , 2003, Developmental cell.
[15] Timothy J Mitchison,et al. Small‐Molecule Screening and Profiling by Using Automated Microscopy , 2005, Chembiochem : a European journal of chemical biology.
[16] Lani F. Wu,et al. Multidimensional Drug Profiling By Automated Microscopy , 2004, Science.
[17] M. Glotzer,et al. Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity. , 2002, Developmental cell.
[18] M. Basseville. Distance measures for signal processing and pattern recognition , 1989 .
[19] Chen Lin,et al. Intelligent Interfaces for Mining Large-Scale RNAi-HCS Image Databases , 2007, 2007 IEEE 7th International Symposium on BioInformatics and BioEngineering.
[20] Robert F Murphy,et al. Automated interpretation of protein subcellular location patterns. , 2006, International review of cytology.
[21] John A. Tallarico,et al. Integrating high-content screening and ligand-target prediction to identify mechanism of action. , 2008, Nature chemical biology.
[22] Stephan R. Sain,et al. Multi-dimensional Density Estimation , 2004 .
[23] Robert Tibshirani,et al. Estimating the number of clusters in a data set via the gap statistic , 2000 .
[24] Anne E Carpenter,et al. Cell microarrays and RNA interference chip away at gene function , 2005, Nature Genetics.
[25] Stephen T. C. Wong,et al. Cellular Phenotype Recognition for High-Content RNA Interference Genome-Wide Screening , 2008, Journal of biomolecular screening.
[26] M V Boland,et al. Automated analysis of patterns in fluorescence-microscope images. , 1999, Trends in cell biology.
[27] Ian T. Jolliffe,et al. Principal Component Analysis , 2002, International Encyclopedia of Statistical Science.
[28] Robert F. Murphy,et al. A neural network classifier capable of recognizing the patterns of all major subcellular structures in fluorescence microscope images of HeLa cells , 2001, Bioinform..
[29] M V Boland,et al. Automated recognition of patterns characteristic of subcellular structures in fluorescence microscopy images. , 1998, Cytometry.
[30] R. Wollman,et al. High throughput microscopy: from raw images to discoveries , 2007, Journal of Cell Science.
[31] H. Erfle,et al. High-throughput RNAi screening by time-lapse imaging of live human cells , 2006, Nature Methods.
[32] J. Engel,et al. Focal adhesion components are essential for mammalian cell cytokinesis , 2008, Cell cycle.
[33] T. Heino,et al. Drosophila α-actinin in ovarian follicle cells is regulated by EGFR and Dpp signalling and required for cytoskeletal remodelling , 2006, Mechanisms of Development.
[34] Lani F. Wu,et al. Image-based multivariate profiling of drug responses from single cells , 2007, Nature Methods.
[35] R. A. Leibler,et al. On Information and Sufficiency , 1951 .
[36] Xiaobo Zhou,et al. Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens , 2008, BMC Bioinformatics.
[37] A. Poustka,et al. A microscope‐based screening platform for large‐scale functional protein analysis in intact cells , 2003, FEBS letters.
[38] Paul Martin,et al. The small GTPase Rac plays multiple roles in epithelial sheet fusion--dynamic studies of Drosophila dorsal closure. , 2005, Developmental biology.
[39] Shigeo Abe DrEng. Pattern Classification , 2001, Springer London.
[40] A. Coulson,et al. Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans , 2005, Nature.
[41] M. Glotzer,et al. Animal cell cytokinesis. , 2001, Annual review of cell and developmental biology.