Minimal residual disease-guided therapy in childhood acute lymphoblastic leukemia.

### Case 1 A 3-year-old boy presented with a leukocyte count of 5.9 × 109/L and was found to have near-haploid B-lineage acute lymphoblastic leukemia (ALL) with a 27, X, +Y, +13, +18, +21 karyotype. He was enrolled in the St. Jude Children’s Research Hospital Total Therapy XV study. After 19

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