Bone marrow-derived cells play a major role in kidney fibrosis via proliferation and differentiation in the infiltrated site.

[1]  K. Dhaliwal,et al.  Macrophage/monocyte depletion by clodronate, but not diphtheria toxin, improves renal ischemia/reperfusion injury in mice. , 2012, Kidney international.

[2]  H. Anders,et al.  Renal microenvironments and macrophage phenotypes determine progression or resolution of renal inflammation and fibrosis. , 2011, Kidney international.

[3]  Liqun He,et al.  CXCL16 recruits bone marrow-derived fibroblast precursors in renal fibrosis. , 2011, Journal of the American Society of Nephrology : JASN.

[4]  R. Bucala,et al.  Fibrocytes: emerging effector cells in chronic inflammation , 2011, Nature Reviews Immunology.

[5]  J. Bonventre,et al.  Repair of injured proximal tubule does not involve specialized progenitors , 2011, Proceedings of the National Academy of Sciences.

[6]  E. Neilson,et al.  Mechanisms of tubulointerstitial fibrosis. , 2010, Journal of the American Society of Nephrology : JASN.

[7]  Luke Barron,et al.  Macrophages: Master Regulators of Inflammation and Fibrosis , 2010, Seminars in liver disease.

[8]  M. Kuwana,et al.  Derivation of multipotent progenitors from human circulating CD14+ monocytes. , 2010, Experimental hematology.

[9]  D. Harris,et al.  IL-10/TGF-beta-modified macrophages induce regulatory T cells and protect against adriamycin nephrosis. , 2010, Journal of the American Society of Nephrology : JASN.

[10]  K. Park,et al.  Reactive oxygen species differently regulate renal tubular epithelial and interstitial cell proliferation after ischemia and reperfusion injury. , 2010, American journal of physiology. Renal physiology.

[11]  J. Lord,et al.  Distinct Types of Fibrocyte Can Differentiate from Mononuclear Cells in the Presence and Absence of Serum , 2010, PloS one.

[12]  J. Duffield,et al.  Bone Marrow Ly6Chigh Monocytes Are Selectively Recruited to Injured Kidney and Differentiate into Functionally Distinct Populations1 , 2009, The Journal of Immunology.

[13]  K. Schmidbauer,et al.  CD4+ T cells control the differentiation of Gr1+ monocytes into fibrocytes , 2009, Proceedings of the National Academy of Sciences.

[14]  K. Park,et al.  Reactive oxygen species/oxidative stress contributes to progression of kidney fibrosis following transient ischemic injury in mice. , 2009, American journal of physiology. Renal physiology.

[15]  T. Hewitson.  Renal tubulointerstitial fibrosis: common but never simple. , 2009, American journal of physiology. Renal physiology.

[16]  B. Thornhill,et al.  Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy. , 2009, Kidney international.

[17]  Jeen-Woo Park,et al.  Increased superoxide formation induced by irradiation preconditioning triggers kidney resistance to ischemia-reperfusion injury in mice. , 2009, American journal of physiology. Renal physiology.

[18]  J. Ingelfinger,et al.  Apocynin attenuates tubular apoptosis and tubulointerstitial fibrosis in transgenic mice independent of hypertension. , 2009, Kidney international.

[19]  H. van Goor,et al.  Macrophage diversity in renal injury and repair. , 2008, The Journal of clinical investigation.

[20]  S. Reese,et al.  Nox‐2 Is a Modulator of Fibrogenesis in Kidney Allografts , 2008, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[21]  K. Chung,et al.  Increased circulating fibrocytes in asthma with chronic airflow obstruction. , 2008, American journal of respiratory and critical care medicine.

[22]  Z. Guo,et al.  Advanced oxidation protein products promote inflammation in diabetic kidney through activation of renal nicotinamide adenine dinucleotide phosphate oxidase. , 2008, Endocrinology.

[23]  K. Park,et al.  Infiltrated Macrophages Contribute to Recovery After Ischemic Injury But Not to Ischemic Preconditioning in Kidneys , 2008, Transplantation.

[24]  T. Wynn,et al.  Cellular and molecular mechanisms of fibrosis , 2008, The Journal of pathology.

[25]  P. Boor,et al.  Treatment targets in renal fibrosis. , 2007, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[26]  Y. Wang,et al.  Ex vivo programmed macrophages ameliorate experimental chronic inflammatory renal disease. , 2007, Kidney international.

[27]  A. Bellini,et al.  The role of the fibrocyte, a bone marrow-derived mesenchymal progenitor, in reactive and reparative fibroses , 2007, Laboratory Investigation.

[28]  S. Ricardo,et al.  The Contribution of Bone Marrow‐Derived Cells to the Development of Renal Interstitial Fibrosis , 2007, Stem cells.

[29]  S. Kaneko,et al.  Secondary lymphoid tissue chemokine (SLC/CCL21)/CCR7 signaling regulates fibrocytes in renal fibrosis , 2006, Proceedings of the National Academy of Sciences.

[30]  Raghu Kalluri,et al.  Fibroblasts in cancer , 2006, Nature Reviews Cancer.

[31]  R. Alon,et al.  Immune cell migration in inflammation: present and future therapeutic targets , 2005, Nature Immunology.

[32]  Paul Martin,et al.  Inflammatory cells during wound repair: the good, the bad and the ugly. , 2005, Trends in cell biology.

[33]  L. Hsiao,et al.  Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells. , 2005, The Journal of clinical investigation.

[34]  M. Stacey,et al.  Fibrocytes contribute to the myofibroblast population in wounded skin and originate from the bone marrow. , 2005, Experimental cell research.

[35]  S. K. Woo,et al.  Maturation of TonEBP expression in developing rat kidney. , 2004, American journal of physiology. Renal physiology.

[36]  F. Cheema,et al.  The renal papilla is a niche for adult kidney stem cells. , 2004, The Journal of clinical investigation.

[37]  T. Wynn.  Fibrotic disease and the TH1/TH2 paradigm , 2004, Nature Reviews Immunology.

[38]  K. Matsushima,et al.  Blockade of CCR2 ameliorates progressive fibrosis in kidney. , 2004, The American journal of pathology.

[39]  Y. Nojima,et al.  Identification of renal progenitor-like tubular cells that participate in the regeneration processes of the kidney. , 2003, Journal of the American Society of Nephrology : JASN.

[40]  K. Channon,et al.  A Myocardial Nox2 Containing NAD(P)H Oxidase Contributes to Oxidative Stress in Human Atrial Fibrillation , 2003, Circulation research.

[41]  M. Linton,et al.  Absence of angiotensin II type 1 receptor in bone marrow-derived cells is detrimental in the evolution of renal fibrosis. , 2002, The Journal of clinical investigation.

[42]  Chad Johnson,et al.  Novel role of gp91(phox)-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis. , 2002, Circulation research.

[43]  B. Thornhill,et al.  Selectins mediate macrophage infiltration in obstructive nephropathy in newborn mice. , 2002, Kidney international.

[44]  K. Park,et al.  Prevention of Kidney Ischemia/Reperfusion-induced Functional Injury, MAPK and MAPK Kinase Activation, and Inflammation by Remote Transient Ureteral Obstruction* , 2002, The Journal of Biological Chemistry.

[45]  Sunil Badve,et al.  Derivation of hepatocytes from bone marrow cells in mice after radiation‐induced myeloablation , 2000, Hepatology.

[46]  F. Strutz,et al.  Identification and characterization of a fibroblast marker: FSP1 , 1995, The Journal of cell biology.

[47]  J. Stolk,et al.  Characteristics of the inhibition of NADPH oxidase activation in neutrophils by apocynin, a methoxy-substituted catechol. , 1994, American journal of respiratory cell and molecular biology.

[48]  H. Gratzner,et al.  Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication. , 1982, Science.

[49]  S. Holdsworth,et al.  Abrogation of macrophage-dependent injury in experimental glomerulonephritis in the rabbit. Use of an antimacrophage serum. , 1981, The Journal of clinical investigation.

[50]  G. Navis,et al.  Bone marrow-derived myofibroblasts contribute to the renal interstitial myofibroblast population and produce procollagen I after ischemia/reperfusion in rats. , 2007, Journal of the American Society of Nephrology : JASN.