Live imaging analysis of human gastric epithelial spheroids reveals spontaneous rupture, rotation and fusion events

[1]  J. Gripentrog,et al.  Slug and Snail have differential effects in directing colonic epithelial wound healing and partially mediate the restitutive effects of butyrate. , 2019, American journal of physiology. Gastrointestinal and liver physiology.

[2]  R. Wilkinson,et al.  A Novel Gastric Spheroid Co-culture Model Reveals Chemokine-Dependent Recruitment of Human Dendritic Cells to the Gastric Epithelium , 2019, Cellular and molecular gastroenterology and hepatology.

[3]  M. Pierzchalska,et al.  The migration and fusion events related to ROCK activity strongly influence the morphology of chicken embryo intestinal organoids , 2018, Protoplasma.

[4]  M. Moyer,et al.  Epithelial TNF Receptor Signaling Promotes Mucosal Repair in Inflammatory Bowel Disease , 2017, The Journal of Immunology.

[5]  Michael S. Behnke,et al.  WRN conditioned media is sufficient for in vitro propagation of intestinal organoids from large farm and small companion animals , 2017, Biology Open.

[6]  A. Todisco,et al.  NOTCH1 and NOTCH2 regulate epithelial cell proliferation in mouse and human gastric corpus. , 2017, American journal of physiology. Gastrointestinal and liver physiology.

[7]  M. Medvedovic,et al.  The Development of Spasmolytic Polypeptide/TFF2-Expressing Metaplasia (SPEM) During Gastric Repair Is Absent in the Aged Stomach , 2016, Cellular and molecular gastroenterology and hepatology.

[8]  Jason R Spence,et al.  Organoid Models of Human Gastrointestinal Development and Disease. , 2016, Gastroenterology.

[9]  W. Garrett,et al.  Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut , 2016, Science.

[10]  A. Louvi,et al.  Notch1 and Notch2 receptors regulate mouse and human gastric antral epithelial cell homoeostasis , 2016, Gut.

[11]  L. Eckmann,et al.  Regulation of Rac1 and Reactive Oxygen Species Production in Response to Infection of Gastrointestinal Epithelia , 2016, PLoS pathogens.

[12]  S. Santhanam,et al.  CD44 and TLR4 mediate hyaluronic acid regulation of Lgr5+ stem cell proliferation, crypt fission, and intestinal growth in postnatal and adult mice. , 2015, American journal of physiology. Gastrointestinal and liver physiology.

[13]  T. Giordano,et al.  Notch signaling regulates gastric antral LGR5 stem cell function , 2015, The EMBO journal.

[14]  Hans Clevers,et al.  SnapShot: Growing Organoids from Stem Cells , 2015, Cell.

[15]  R. Shivdasani,et al.  The use of murine‐derived fundic organoids in studies of gastric physiology , 2015, The Journal of physiology.

[16]  G. Boivin,et al.  CD44 Plays a Functional Role in Helicobacter pylori-induced Epithelial Cell Proliferation , 2015, PLoS pathogens.

[17]  H. Mollenkopf,et al.  A novel human gastric primary cell culture system for modelling Helicobacter pylori infection in vitro , 2014, Gut.

[18]  Michael Schumacher,et al.  Modeling human development and disease in pluripotent stem cell-derived gastric organoids , 2014, Nature.

[19]  P. Mannon,et al.  Human Gastric Epithelial Cells Contribute to Gastric Immune Regulation by Providing Retinoic Acid to Dendritic Cells , 2014, Mucosal Immunology.

[20]  H. Miyoshi,et al.  Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays , 2014, Gut.

[21]  Nick Barker,et al.  Ex vivo culture of the intestinal epithelium: strategies and applications , 2014, Gut.

[22]  Toshiro Sato,et al.  Establishment of Gastrointestinal Epithelial Organoids , 2013, Current protocols in mouse biology.

[23]  Hiroyuki Miyoshi,et al.  In vitro expansion and genetic modification of gastrointestinal stem cells in spheroid culture , 2013, Nature Protocols.

[24]  H. Clevers,et al.  Generation of BAC Transgenic Epithelial Organoids , 2013, PloS one.

[25]  P. Mannon,et al.  Helicobacter pylori Infection Inhibits Phagocyte Clearance of Apoptotic Gastric Epithelial Cells , 2013, The Journal of Immunology.

[26]  R. Hynds,et al.  Concise Review: The Relevance of Human Stem Cell‐Derived Organoid Models for Epithelial Translational Medicine , 2013, Stem cells.

[27]  Terry P Yamaguchi,et al.  Wnt5a Potentiates TGF-β Signaling to Promote Colonic Crypt Regeneration After Tissue Injury , 2012, Science.

[28]  Matthias Stelzner,et al.  A nomenclature for intestinal in vitro cultures. , 2012, American journal of physiology. Gastrointestinal and liver physiology.

[29]  Hans Clevers,et al.  A functional CFTR assay using primary cystic fibrosis intestinal organoids , 2013, Nature Medicine.

[30]  Mahmoud Omid,et al.  Principles and Applications of Light Backscattering Imaging in Quality Evaluation of Agro-food Products: a Review , 2012, Food and Bioprocess Technology.

[31]  S. Ichinose,et al.  Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell , 2012, Nature Medicine.

[32]  M. Iizuka,et al.  Wound healing of intestinal epithelial cells. , 2011, World journal of gastroenterology.

[33]  Rashmi Chandra,et al.  Characterization of basal pseudopod-like processes in ileal and colonic PYY cells , 2011, Journal of Molecular Histology.

[34]  H. Kleinman,et al.  Advancing science and technology via 3D culture on basement membrane matrix , 2009, Journal of cellular physiology.

[35]  E. Solcia,et al.  Evidence for Transepithelial Dendritic Cells in Human H. pylori Active Gastritis , 2009, Helicobacter.

[36]  Calvin J Kuo,et al.  Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche , 2009, Nature Medicine.

[37]  H. Clevers,et al.  Single Lgr5 stem cells build crypt–villus structures in vitro without a mesenchymal niche , 2009, Nature.

[38]  Trevor Douglas,et al.  Particle Assembly and Ultrastructural Features Associated with Replication of the Lytic Archaeal Virus Sulfolobus Turreted Icosahedral Virus , 2009, Journal of Virology.

[39]  J. Sørensen,et al.  The lateral intercellular space as osmotic coupling compartment in isotonic transport , 2009, Acta physiologica.

[40]  David M. Sabatini,et al.  The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1 , 2008, Science.

[41]  Michael K. Wendt,et al.  CXCL12 activation of CXCR4 regulates mucosal host defense through stimulation of epithelial cell migration and promotion of intestinal barrier integrity. , 2005, American journal of physiology. Gastrointestinal and liver physiology.

[42]  William C Hahn,et al.  Lentivirus-delivered stable gene silencing by RNAi in primary cells. , 2003, RNA.

[43]  J. Gordon,et al.  Gastric epithelial morphogenesis in normal and transgenic mice. , 1997, The American journal of physiology.

[44]  J. Heath,et al.  EPITHELIAL CELL MIGRATION IN THE INTESTINE , 1996, Cell biology international.

[45]  T. Pohl,et al.  Rapid quantification of lymphocyte subsets in heterogeneous cell populations by flow cytometry. , 1994, Cytometry.

[46]  H. Clevers,et al.  Identification and cloning of TCF‐1, a T lymphocyte‐specific transcription factor containing a sequence‐specific HMG box. , 1991, The EMBO journal.

[47]  J. Diamond,et al.  Role of Long Extracellular Channels in Fluid Transport across Epithelia , 1966, Nature.

[48]  M. Lipkin CELL REPLICATION IN THE GASTROINTESTINAL TRACT OF MAN. , 1965, Gastroenterology.

[49]  B. Creamer,et al.  The turnover and shedding of epithelial cells , 1961, Gut.

[50]  H. Miyoshi Wnt-expressing cells in the intestines: guides for tissue remodeling , 2017, Journal of biochemistry.

[51]  Hans Clevers,et al.  In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection. , 2015, Gastroenterology.

[52]  A. Watson,et al.  Epithelial Cell Shedding and Barrier Function : A Matter of Life and Death at the Small Intestinal Villus Tip , 2015 .

[53]  M. McNiven Breaking away: matrix remodeling from the leading edge. , 2013, Trends in cell biology.

[54]  J. Scott,et al.  The fine structure of human gastric parietal cells , 2005, The American Journal of Digestive Diseases.

[55]  W. Silen,et al.  Mechanisms for rapid re-epithelialization of the gastric mucosal surface. , 1985, Annual review of physiology.

[56]  D. Burgess Structure of the epithelial - mesenchymal interface during early morphogenesis of the chick duodenum. , 1976, Tissue & cell.

[57]  P. Zeitoun,et al.  Ultrastructure of the gastric mucosa in human hemochromatosis. , 1967, Scandinavian journal of gastroenterology.

[58]  R. Corpron The ultrastructure of the gastric mucosa in normal and hypophysectomized rats. , 1966, The American journal of anatomy.