An HMGA2-IGF2BP2 axis regulates myoblast proliferation and myogenesis.

[1]  J. Avruch,et al.  mTOR phosphorylates IMP2 to promote IGF2 mRNA translation by internal ribosomal entry. , 2011, Genes & development.

[2]  Y. Yen,et al.  High-Mobility Group A2 Protein Modulates hTERT Transcription To Promote Tumorigenesis , 2011, Molecular and Cellular Biology.

[3]  D. Glass,et al.  Molecular mechanisms and treatment options for muscle wasting diseases. , 2011, Annual review of pharmacology and toxicology.

[4]  Valentina Proserpio,et al.  TNF/p38α/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration. , 2010, Cell stem cell.

[5]  G. Shefer,et al.  The depletion of skeletal muscle satellite cells with age is concomitant with reduced capacity of single progenitors to produce reserve progeny. , 2010, Developmental biology.

[6]  Scott B. Dewell,et al.  Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP , 2010, Cell.

[7]  A. Fusco,et al.  HMGA and cancer. , 2010, Biochimica et biophysica acta.

[8]  K. Chada,et al.  In vivo modulation of HMGA2 expression. , 2010, Biochimica et biophysica acta.

[9]  T. Hansen,et al.  IGF2 mRNA-binding protein 2: biological function and putative role in type 2 diabetes. , 2009, Journal of molecular endocrinology.

[10]  J. Hescheler,et al.  The High Mobility Group Protein HMGA2: A Co-Regulator of Chromatin Structure and Pluripotency in Stem Cells? , 2009, Stem Cell Reviews and Reports.

[11]  John K. Hall,et al.  Syndecan-4-expressing muscle progenitor cells in the SP engraft as satellite cells during muscle regeneration. , 2009, Cell stem cell.

[12]  M. Nakao,et al.  HMGA2 maintains oncogenic RAS-induced epithelial-mesenchymal transition in human pancreatic cancer cells. , 2009, The American journal of pathology.

[13]  Sean J. Morrison,et al.  Hmga2 Promotes Neural Stem Cell Self-Renewal in Young but Not Old Mice by Reducing p16Ink4a and p19Arf Expression , 2008, Cell.

[14]  Helen M Blau,et al.  Cell therapies for muscular dystrophy. , 2008, The New England journal of medicine.

[15]  Y. Hiroi,et al.  A crucial role of a high mobility group protein HMGA2 in cardiogenesis , 2008, Nature Cell Biology.

[16]  M. Rudnicki,et al.  The molecular regulation of muscle stem cell function. , 2008, Cold Spring Harbor symposia on quantitative biology.

[17]  M. Rudnicki,et al.  Skeletal muscle satellite cells and adult myogenesis. , 2007, Current opinion in cell biology.

[18]  A. Uezumi,et al.  Molecular Signature of Quiescent Satellite Cells in Adult Skeletal Muscle , 2007, Stem cells.

[19]  T. Rando,et al.  Intrinsic Changes and Extrinsic Influences of Myogenic Stem Cell Function During Aging , 2007, Stem Cell Reviews.

[20]  R. Sciot,et al.  HMGA2 Regulates Transcription of the Imp2 Gene via an Intronic Regulatory Element in Cooperation with Nuclear Factor-κB , 2007, Molecular Cancer Research.

[21]  G. Viglietto,et al.  Haploinsufficiency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice. , 2006, Cancer research.

[22]  F. Bost,et al.  A new role for the oncogenic high-mobility group A2 transcription factor in myogenesis of embryonic stem cells , 2005, Oncogene.

[23]  I. Weissman,et al.  Rejuvenation of aged progenitor cells by exposure to a young systemic environment , 2005, Nature.

[24]  B. Olwin,et al.  Pax-7 up-regulation inhibits myogenesis and cell cycle progression in satellite cells: a potential mechanism for self-renewal. , 2004, Developmental biology.

[25]  I. Weissman,et al.  Isolation of Adult Mouse Myogenic Progenitors Functional Heterogeneity of Cells within and Engrafting Skeletal Muscle , 2004, Cell.

[26]  T. Partridge,et al.  Muscle satellite cells adopt divergent fates , 2004, The Journal of cell biology.

[27]  Y. Tanabe,et al.  Skeletal muscle pathology in X chromosome-linked muscular dystrophy (mdx) mouse , 2004, Acta Neuropathologica.

[28]  M. Luster,et al.  Physiological role of tumor necrosis factor α in traumatic muscle injury , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[29]  D J Glass,et al.  Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy , 2001, Science.

[30]  J. Black,et al.  Sp1 and krüppel‐like factor family of transcription factors in cell growth regulation and cancer , 2001, Journal of cellular physiology.

[31]  J. Dimario,et al.  Two distal Sp1-binding cis-elements regulate fibroblast growth factor receptor 1 (FGFR1) gene expression in myoblasts. , 2001, Gene.

[32]  K. Chada,et al.  In vivo modulation of Hmgic reduces obesity , 2000, Nature Genetics.

[33]  N. Rosenthal,et al.  Proliferation precedes differentiation in IGF-I-stimulated myogenesis , 1996, The Journal of cell biology.

[34]  D. Gillespie,et al.  c-Myc inhibits myogenic differentiation and myoD expression by a mechanism which can be dissociated from cell transformation. , 1994, Oncogene.

[35]  M. Kaleko,et al.  Type‐1 insulin‐like growth factor receptor overexpression produces dual effects on myoblast proliferation and differentiation , 1994, Journal of cellular physiology.

[36]  J. Baker,et al.  Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r) , 1993, Cell.

[37]  L. S. Quinn,et al.  Overexpression of the human type-1 insulin-like growth factor receptor in rat L6 myoblasts induces ligand-dependent cell proliferation and inhibition of differentiation. , 1993, Experimental cell research.

[38]  B. Wold,et al.  c-myc inhibition of MyoD and myogenin-initiated myogenic differentiation , 1991, Molecular and cellular biology.

[39]  J. V. Van Wyk,et al.  Biphasic concentration dependency of stimulation of myoblast differentiation by somatomedins. , 1986, The American journal of physiology.

[40]  K. Moore,et al.  X chromosome-linked muscular dystrophy (mdx) in the mouse. , 1984, Proceedings of the National Academy of Sciences of the United States of America.