Discovery of amphotericin B, an antifungal drug as tyrosinase inhibitor with potent anti-melanogenic activity.

[1]  S. Luang,et al.  Anserine/Carnosine-Rich Extract from Thai Native Chicken Suppresses Melanogenesis via Activation of ERK Signaling Pathway , 2022, Molecules.

[2]  Jun Li,et al.  Nilotinib in Parkinson's disease: A systematic review and meta-analysis , 2022, Frontiers in Aging Neuroscience.

[3]  L. Ouyang,et al.  Discovery of Tyrosinase Inhibitors: Structure-Based Virtual Screening and Biological Evaluation , 2022, Pharmaceutical Fronts.

[4]  H. Choi,et al.  Decursin prevents melanogenesis by suppressing MITF expression through the regulation of PKA/CREB, MAPKs, and PI3K/Akt/GSK-3β cascades. , 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[5]  T. Rungrotmongkol,et al.  In Silico Elucidation of Potent Inhibitors and Rational Drug Design against SARS-CoV-2 Papain-like Protease , 2021, The journal of physical chemistry. B.

[6]  T. Rungrotmongkol,et al.  Molecular encapsulation of a key odor-active 2-acetyl-1-pyrroline in aromatic rice with β-cyclodextrin derivatives , 2021 .

[7]  Cha Young Kim,et al.  Inhibition of melanogenesis by Aster yomena callus pellet extract in melanoma cells and patients with skin pigmentation , 2021, International journal of medical sciences.

[8]  Thanapon Charoenwongpaiboon,et al.  Molecular basis of the new COVID-19 target neuropilin-1 in complex with SARS-CoV-2 S1 C-end rule peptide and small-molecule antagonists , 2021, Journal of Molecular Liquids.

[9]  T. Rungrotmongkol,et al.  Identification of Vinyl Sulfone Derivatives as EGFR Tyrosine Kinase Inhibitor: In Vitro and In Silico Studies , 2021, Molecules.

[10]  T. Rungrotmongkol,et al.  Discovery of novel JAK2 and EGFR inhibitors from a series of thiazole-based chalcone derivatives. , 2021, RSC medicinal chemistry.

[11]  K. Sakamoto,et al.  α-Mangostin suppressed melanogenesis in B16F10 murine melanoma cells through GSK3β and ERK signaling pathway , 2021, Biochemistry and biophysics reports.

[12]  Y. Jeon,et al.  Padina boryana, a brown alga from the Maldives: inhibition of α-MSH-stimulated melanogenesis via the activation of ERK in B16F10 cells , 2020 .

[13]  T. Rungrotmongkol,et al.  Binding hot spot and activation mechanism of maltitol and lactitol towards the human sweet taste receptor. , 2020, Journal of agricultural and food chemistry.

[14]  G. Aliev,et al.  The Association of Sleep Disorders, Obesity, and Sleep-Related Hypoxia with Cancer. , 2019, Current topics in medicinal chemistry.

[15]  G. Connett,et al.  Lumacaftor-ivacaftor in the treatment of cystic fibrosis: design, development and place in therapy , 2019, Drug design, development and therapy.

[16]  D. Brǎnișteanu,et al.  Synthesis and physiological implications of melanic pigments. , 2019, Oncology letters.

[17]  J. Choi,et al.  Discovery of a Highly Potent Tyrosinase Inhibitor, Luteolin 5-O-β-d-Glucopyranoside, Isolated from Cirsium japonicum var. maackii (Maxim.) Matsum., Korean Thistle: Kinetics and Computational Molecular Docking Simulation , 2018, ACS Omega.

[18]  Jianmin Chen,et al.  Molecular inhibitory mechanism of dihydromyricetin on mushroom tyrosinase , 2018, Journal of biomolecular structure & dynamics.

[19]  V. Hearing,et al.  Inhibition of Human Tyrosinase Requires Molecular Motifs Distinctively Different from Mushroom Tyrosinase. , 2018, The Journal of investigative dermatology.

[20]  S. Cho,et al.  Phytol suppresses melanogenesis through proteasomal degradation of MITF via the ROS-ERK signaling pathway. , 2018, Chemico-biological interactions.

[21]  D. Salvatore,et al.  Role of Digoxin in Atrial Fibrillation , 2017, Journal of pharmacy practice.

[22]  M. Soler‐Lopez,et al.  Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis , 2017, Angewandte Chemie.

[23]  D. Spandidos,et al.  Soyasaponin Ag inhibits α-MSH-induced melanogenesis in B16F10 melanoma cells via the downregulation of TRP-2 , 2017, International journal of molecular medicine.

[24]  S. Kim,et al.  Gomisin N Inhibits Melanogenesis through Regulating the PI3K/Akt and MAPK/ERK Signaling Pathways in Melanocytes , 2017, International journal of molecular sciences.

[25]  V. Namasivayam,et al.  Skin whitening agents: medicinal chemistry perspective of tyrosinase inhibitors , 2017, Journal of enzyme inhibition and medicinal chemistry.

[26]  Zhixue Liu,et al.  Phosphorylation of MITF by AKT affects its downstream targets and causes TP53-dependent cell senescence. , 2016, The international journal of biochemistry & cell biology.

[27]  Suman Sirimulla,et al.  AutoDock VinaXB: implementation of XBSF, new empirical halogen bond scoring function, into AutoDock Vina , 2016, Journal of Cheminformatics.

[28]  Mubashir Hassan,et al.  Exploration of Novel Human Tyrosinase Inhibitors by Molecular Modeling, Docking and Simulation Studies , 2016, Interdisciplinary Sciences: Computational Life Sciences.

[29]  C. Simmerling,et al.  ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB. , 2015, Journal of chemical theory and computation.

[30]  Thanigaimalai Pillaiyar,et al.  Inhibitors of melanogenesis: a patent review (2009 – 2014) , 2015, Expert opinion on therapeutic patents.

[31]  M. Ganjali,et al.  A new insight into mushroom tyrosinase inhibitors: docking, pharmacophore-based virtual screening, and molecular modeling studies , 2015, Journal of biomolecular structure & dynamics.

[32]  Estibaliz Sansinenea,et al.  Melanin: a photoprotection for Bacillus thuringiensis based biopesticides , 2015, Biotechnology Letters.

[33]  Nai-Wan Hsiao,et al.  Discovery of Highly Potent Tyrosinase Inhibitor, T1, with Significant Anti-Melanogenesis Ability by zebrafish in vivo Assay and Computational Molecular Modeling , 2015, Scientific Reports.

[34]  W. Welsh,et al.  Novel Virtual Screening Approach for the Discovery of Human Tyrosinase Inhibitors , 2014, PloS one.

[35]  Hyoung-Kwon Cho,et al.  Melanogenesis inhibitory effect of aerial part of Pueraria thunbergiana in vitro and in vivo , 2014, Archives of Dermatological Research.

[36]  Shu-Jen Chang,et al.  [6]-Shogaol Inhibits α-MSH-Induced Melanogenesis through the Acceleration of ERK and PI3K/Akt-Mediated MITF Degradation , 2014, BioMed research international.

[37]  H. Tomoda,et al.  Inhibition of tyrosinase activity and melanine pigmentation by 2-hydroxytyrosol , 2014, Acta pharmaceutica Sinica. B.

[38]  Tzu-rong Su,et al.  Inhibition of Melanogenesis by Gallic Acid: Possible Involvement of the PI3K/Akt, MEK/ERK and Wnt/β-Catenin Signaling Pathways in B16F10 Cells , 2013, International journal of molecular sciences.

[39]  Daniel R Roe,et al.  PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data. , 2013, Journal of chemical theory and computation.

[40]  Brice E. Uno,et al.  C2'-OH of amphotericin B plays an important role in binding the primary sterol of human cells but not yeast cells. , 2013, Journal of the American Chemical Society.

[41]  Ross C. Walker,et al.  An overview of the Amber biomolecular simulation package , 2013 .

[42]  Holger Gohlke,et al.  MMPBSA.py: An Efficient Program for End-State Free Energy Calculations. , 2012, Journal of chemical theory and computation.

[43]  Ó. Zaragoza,et al.  It only takes one to do many jobs: Amphotericin B as antifungal and immunomodulatory drug , 2012, Front. Microbio..

[44]  Yung-Hyun Choi,et al.  Partially purified components of Nardostachys chinensis suppress melanin synthesis through ERK and Akt signaling pathway with cAMP down-regulation in B16F10 cells. , 2011, Journal of ethnopharmacology.

[45]  D. Kalonia,et al.  Long- and Short-Range Electrostatic Interactions Affect the Rheology of Highly Concentrated Antibody Solutions , 2009, Pharmaceutical Research.

[46]  Gerhard Klebe,et al.  PDB2PQR: expanding and upgrading automated preparation of biomolecular structures for molecular simulations , 2007, Nucleic Acids Res..

[47]  M. Ichihashi,et al.  Approaches to identify inhibitors of melanin biosynthesis via the quality control of tyrosinase. , 2007, The Journal of investigative dermatology.

[48]  Francisco Solano,et al.  Hypopigmenting agents: an updated review on biological, chemical and clinical aspects. , 2006, Pigment cell research.

[49]  Lu Zhao,et al.  The importance of the depth distribution of melanin in skin for DNA protection and other photobiological processes. , 2006, Journal of photochemistry and photobiology. B, Biology.

[50]  C. Venkatachalam,et al.  LigScore: a novel scoring function for predicting binding affinities. , 2005, Journal of molecular graphics & modelling.

[51]  Hang-Ching Lin,et al.  Identifying 6,7,4′-Trihydroxyisoflavone as a Potent Tyrosinase Inhibitor , 2005, Bioscience, biotechnology, and biochemistry.

[52]  K. Wakamatsu,et al.  Quantitative analysis of eumelanin and pheomelanin in humans, mice, and other animals: a comparative review. , 2003, Pigment cell research.

[53]  T. Darden,et al.  The effect of long‐range electrostatic interactions in simulations of macromolecular crystals: A comparison of the Ewald and truncated list methods , 1993 .

[54]  T. Darden,et al.  Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems , 1993 .

[55]  W. L. Jorgensen,et al.  Comparison of simple potential functions for simulating liquid water , 1983 .

[56]  G. Ciccotti,et al.  Numerical Integration of the Cartesian Equations of Motion of a System with Constraints: Molecular Dynamics of n-Alkanes , 1977 .

[57]  Maciej Baginski,et al.  Molecular modelling of membrane activity of amphotericin B, a polyene macrolide antifungal antibiotic. , 2005, Acta biochimica Polonica.