Fragment C of Tetanus Toxin: New Insights into Its Neuronal Signaling Pathway
暂无分享,去创建一个
Raquel Manzano | Sara Oliván | Rosario Osta | R. Manzano | R. Osta | P. Zaragoza | A. Calvo | S. Oliván | J. Aguilera | Ana C. Calvo | Pilar Zaragoza | José Aguilera
[1] P. Emsley,et al. The Structures of the HC Fragment of Tetanus Toxin with Carbohydrate Subunit Complexes Provide Insight into Ganglioside Binding* , 2000, The Journal of Biological Chemistry.
[2] N. Fairweather,et al. Analysis of mutants of tetanus toxin HC fragment: ganglioside binding, cell binding and retrograde axonal transport properties , 2000, Molecular microbiology.
[3] J. Aguilera,et al. The carboxyl-terminal domain of the heavy chain of tetanus toxin prevents dopaminergic degeneration and improves motor behavior in rats with striatal MPP+-lesions , 2009, Neuroscience Research.
[4] W. E. van Heyningen. The fixation of tetanus toxin by nervous tissue. , 1959, Journal of general microbiology.
[5] L. Simpson,et al. Neuropharmacological characterization of fragment B from tetanus toxin. , 1985, The Journal of pharmacology and experimental therapeutics.
[6] P. Brûlet,et al. A genetic fusion GDNF-C fragment of tetanus toxin prolongs survival in a symptomatic mouse ALS model. , 2008, Restorative neurology and neuroscience.
[7] G. Schiavo,et al. Analysis of retrograde transport in motor neurons reveals common endocytic carriers for tetanus toxin and neurotrophin receptor p75NTR , 2002, The Journal of cell biology.
[8] C. Sherrington. On Reciprocal Innervation of Antagonistic Muscles. Eleventh Note.--Further Observations on Successive Induction , 1908 .
[9] C. Gil,et al. Tetanus toxin modulates serotonin transport in rat-brain neuronal cultures , 2001, Journal of Molecular Neuroscience.
[10] D. Sasaki,et al. In situ scanning probe microscopy studies of tetanus toxin-membrane interactions. , 2006, Biophysical journal.
[11] J. Blasi,et al. HC fragment (C-terminal portion of the heavy chain) of tetanus toxin activates protein kinase C isoforms and phosphoproteins involved in signal transduction. , 2001, The Biochemical journal.
[12] W. Frey,et al. Delivery of Neurotrophic Factors to the Central Nervous System , 2001, Clinical pharmacokinetics.
[13] P. Brûlet,et al. Brain‐derived neurotrophic factor facilitates in vivo internalization of tetanus neurotoxin C‐terminal fragment fusion proteins in mature mouse motor nerve terminals , 2006, The European journal of neuroscience.
[14] T. Helting,et al. Structure of tetanus toxin. N-Terminal amino acid analysis of the two molecular forms of tetanus toxin and its composite chains. , 1979, Biochemical and biophysical research communications.
[15] W. Robberecht,et al. A placebo-controlled trial of insulin-like growth factor-I in amyotrophic lateral sclerosis. European ALS/IGF-I Study Group. , 1998, Neurology.
[16] H. Sugiyama. Clostridium botulinum neurotoxin. , 1980, Microbiological reviews.
[17] J. Barbieri,et al. Gangliosides as High Affinity Receptors for Tetanus Neurotoxin* , 2009, The Journal of Biological Chemistry.
[18] E. A. Wright. The effect of the injection of tetanus toxin into the central nervous system of rabbits. , 1953, Journal of Immunology.
[19] D. Matusica,et al. Proteolytic processing of the p75 neurotrophin receptor: A prerequisite for signalling? , 2011, BioEssays : news and reviews in molecular, cellular and developmental biology.
[20] C. Gil,et al. C-terminal fragment of tetanus toxin heavy chain activates Akt and MEK/ERK signalling pathways in a Trk receptor-dependent manner in cultured cortical neurons. , 2003, The Biochemical journal.
[21] S. Mochida. Protein–protein interactions in neurotransmitter release , 2000, Neuroscience Research.
[22] A. Ortega,et al. Tetanus toxin HC fragment reduces neuronal MPP+ toxicity , 2009, Molecular and Cellular Neuroscience.
[23] Jonathan P. Riley,et al. FUSION OF THE TETANUS TOXIN C FRAGMENT BINDING DOMAIN AND BCL‐XL FOR PROTECTION OF PERIPHERAL NERVE NEURONS , 2008, Neurosurgery.
[24] J. Eccles,et al. The action of tetanus toxin on the inhibition of motoneurones , 1957, The Journal of physiology.
[25] E. Duflot,et al. Low pH induces a hydrophobic domain in the tetanus toxin molecule. , 1984, European journal of biochemistry.
[26] G. Menestrina,et al. Interaction of tetanus toxin with lipid vesicles. Effects of pH, surface charge, and transmembrane potential on the kinetics of channel formation. , 1989, Biophysical journal.
[27] H. Wiegandt,et al. Structure of tetanus toxin. II. Toxin binding to ganglioside. , 1977, The Journal of biological chemistry.
[28] E. Habermann,et al. Clostridial neurotoxins: handling and action at the cellular and molecular level. , 1986, Current topics in microbiology and immunology.
[29] J. Ciriza,et al. Non-viral gene delivery of the GDNF, either alone or fused to the C-fragment of tetanus toxin protein, prolongs survival in a mouse ALS model. , 2012, Restorative neurology and neuroscience.
[30] F. Hughson,et al. SNARE protein structure and function. , 2003, Annual review of cell and developmental biology.
[31] J. Alves,et al. Two carbohydrate binding sites in the H(CC)-domain of tetanus neurotoxin are required for toxicity. , 2003, Journal of molecular biology.
[32] J. Inserte,et al. Inhibition by tetanus toxin of sodium-dependent, high-affinity [3H]5-hydroxytryptamine uptake in rat synaptosomes. , 1999, Biochemical pharmacology.
[33] C. Gil,et al. Activation of signal transduction pathways involving trkA, PLCγ‐1, PKC isoforms and ERK‐1/2 by tetanus toxin , 2000 .
[34] B. Rupp,et al. The 1.61 Angstrom Structure of the Tetanus Toxin Ganglioside Binding Region: Solved by MAD and Mir Phase Combination , 1998 .
[35] J. Johnson,et al. Taxonomy of the Clostridia: ribosomal ribonucleic acid homologies among the species. , 1975, Journal of general microbiology.
[36] Gregory A.Petsko and Dagmar Ringe. Protein structure and function , 2003 .
[37] E. Johnson,et al. Clostridial toxins as therapeutic agents: benefits of nature's most toxic proteins. , 1999, Annual review of microbiology.
[38] Katrin Deinhardt,et al. Tetanus toxin is internalized by a sequential clathrin-dependent mechanism initiated within lipid microdomains and independent of epsin1 , 2006, The Journal of cell biology.
[39] C. Evinger,et al. Transsynaptic retrograde transport of fragment C of tetanus toxin demonstrated by immunohistochemical localization , 1986, Brain Research.
[40] R. Venable,et al. Identification of a binding site for ganglioside on the receptor binding domain of tetanus toxin. , 2002, Biochemistry.
[41] P. Brûlet,et al. Construction of hybrid proteins that migrate retrogradely and transynaptically into the central nervous system. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[42] N. Silman,et al. Tyrosine‐1290 of tetanus neurotoxin plays a key role in its binding to gangliosides and functional binding to neurones , 2001, FEBS letters.
[43] P. Fishman,et al. Retrograde transneuronal transfer of the C-fragment of tetanus toxin , 1987, Brain Research.
[44] A. M. Harvey. The peripheral action of tetanus toxin , 1939, The Journal of physiology.
[45] C. Torda,et al. The effect of tetanus toxin on the choline esterase activity of the muscles of rats , 1939, Journal of Physiology.
[46] V. Krishnan,et al. Identification of novel small molecules that bind to two different sites on the surface of tetanus toxin C fragment. , 2002, Chemical research in toxicology.
[47] M. Martins,et al. Targeted gene delivery into peripheral sensorial neurons mediated by self-assembled vectors composed of poly(ethylene imine) and tetanus toxin fragment c. , 2010, Journal of controlled release : official journal of the Controlled Release Society.
[48] P. Lazarovici,et al. Molecular interactions between micellar polysialogangliosides and affinity-purified tetanotoxins in aqueous solution. , 1987, The Journal of biological chemistry.
[49] Carlos F. Ibáñez,et al. p75 neurotrophin receptor signaling in nervous system injury and degeneration: paradox and opportunity , 2012, Trends in Neurosciences.
[50] P. Brûlet,et al. Neuronal activity-dependent membrane traffic at the neuromuscular junction , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[51] S. Flexner,et al. THE EFFECT OF EOSIN UPON TETANUS TOXIN AND UPON TETANUS IN RATS AND GUINEA-PIGS , 1906, The Journal of experimental medicine.
[52] G. Schiavo,et al. Rab5 and Rab7 Control Endocytic Sorting along the Axonal Retrograde Transport Pathway , 2006, Neuron.
[53] T. Helting,et al. Structure of tetanus toxin: the arrangement of papain digestion products within the heavy chain-light chain framework of extracellular toxin. , 1981, Biochimica et biophysica acta.
[54] P. Emsley,et al. The Crystal Structure of Tetanus Toxin Hc Fragment Complexed with a Synthetic GT1b Analogue Suggests Cross-linking between Ganglioside Receptors and the Toxin* , 2001, The Journal of Biological Chemistry.
[55] C. Gil,et al. The C‐terminal domain of the heavy chain of tetanus toxin rescues cerebellar granule neurones from apoptotic death: involvement of phosphatidylinositol 3‐kinase and mitogen‐activated protein kinase pathways , 2004, Journal of neurochemistry.
[56] S. van Heyningen. Binding of ganglioside by the chains of tetanus toxin , 1976, FEBS letters.
[57] J. Barbieri,et al. Insights into the different catalytic activities of Clostridium neurotoxins. , 2012, Biochemistry.
[58] M. Masserini,et al. Lipid interaction of Tetanus neurotoxin A calorimetric and fluorescence spectroscopy study , 1992, FEBS letters.
[59] E. Yavin,et al. Tetanus toxin‐induced protein kinase C activation and elevated serotonin levels in the perinatal rat brain , 1990, FEBS letters.
[60] P. Leigh,et al. A placebo-controlled trial of insulin-like growth factor-I in amyotrophic lateral sclerosis , 1998, Neurology.
[61] I. Ay,et al. A glial cell line-derived neurotrophic factor (GDNF):tetanus toxin fragment C protein conjugate improves delivery of GDNF to spinal cord motor neurons in mice , 2006, Brain Research.
[62] G. Schiavo,et al. Tetanus and botulinum neurotoxins: mechanism of action and therapeutic uses. , 1999, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
[63] G. Schiavo,et al. Neurotrophins Redirect p75NTR from a Clathrin‐Independent to a Clathrin‐Dependent Endocytic Pathway Coupled to Axonal Transport , 2007, Traffic.
[64] J. Ipsen. The effect of environmental temperature on the reaction of mice to tetanus toxin. , 1951, Journal of Immunology.
[65] F. Fauchereau,et al. Neuronal Targeting of Cardiotrophin-1 by Coupling with Tetanus Toxin C Fragment , 2001, Molecular and Cellular Neuroscience.
[66] W. E. van Heyningen. The fixation of tetanus toxin by ganglioside. , 1963, Biochemical pharmacology.
[67] U. Albus,et al. Interaction Between Tetanus Toxin and Rabbit Kidney: A Comparison with Rat Brain Preparations , 1986, Journal of neurochemistry.
[68] G. Schiavo,et al. Lipid rafts act as specialized domains for tetanus toxin binding and internalization into neurons. , 2001, Molecular biology of the cell.
[69] G. Schiavo,et al. Tetanus Toxin Fragment C Binds to a Protein Present in Neuronal Cell Lines and Motoneurons , 2000, Journal of neurochemistry.
[70] Y. Humeau,et al. How botulinum and tetanus neurotoxins block neurotransmitter release. , 2000, Biochimie.
[71] P. Brûlet,et al. A Non-Viral Vector for Targeting Gene Therapy to Motoneurons in the CNS , 2004, Neurodegenerative Diseases.
[72] A. Burlingame,et al. Electrospray mass spectrometry of neuac oligomers associated with the c fragment of the tetanus toxin , 2006, Journal of the American Society for Mass Spectrometry.
[73] R. Rush,et al. Hybrid Tetanus Toxin C Fragment-Diphtheria Toxin Translocation Domain Allows Specific Gene Transfer into PC12 Cells , 2002, Experimental Neurology.
[74] X. Navarro,et al. Lack of a synergistic effect of a non-viral ALS gene therapy based on BDNF and a TTC fusion molecule , 2011, Orphanet journal of rare diseases.
[75] Mauricio Montal,et al. Botulinum neurotoxin: a marvel of protein design. , 2010, Annual review of biochemistry.
[76] P. Brûlet,et al. Fragment C tetanus toxin: a putative activity-dependent neuroanatomical tracer. , 2003, Acta neurobiologiae experimentalis.
[77] X. Navarro,et al. Fragment C of tetanus toxin, more than a carrier. Novel perspectives in non-viral ALS gene therapy , 2009, Journal of Molecular Medicine.
[78] R. Segal,et al. p75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp , 2002, Nature.
[79] Jay H. Chang,et al. Pathophysiological Mechanisms for Actions of the Neurotrophins , 2006, Brain pathology.
[80] S. Skaper. The biology of neurotrophins, signalling pathways, and functional peptide mimetics of neurotrophins and their receptors. , 2008, CNS & neurological disorders drug targets.
[81] Experiments in examination of the ‘locked‐jaw’ induced by tetanus toxin , 1906, The Journal of physiology.
[82] M. Alava,et al. Tetanus Toxin Enhances Protein Kinase C Activity Translocation and Increases Polyphosphoinositide Hydrolysis in Rat Cerebral Cortex Preparations , 1998, Journal of neurochemistry.
[83] Common binding site for disialyllactose and tri‐peptide in C‐fragment of tetanus neurotoxin , 2005, Proteins.
[84] J. T. Erichsen,et al. Retrograde transneuronal transport properties of fragment C of tetanus toxin , 1990, Neuroscience.