Successful lumbar surgery results in improved psychological well-being: a longitudinal assessment of depressive and anxiety symptoms.

BACKGROUND CONTEXT Preoperative psychological symptoms predict surgical outcomes. The impact of surgical outcomes on psychological well-being, however, has not been delineated. PURPOSE This study aimed to compare pre- with postoperative depressive and anxiety symptoms based on success of surgery, defined as fulfilled expectations and improvement in disability and pain. STUDY DESIGN/SETTING A prospective 2-year longitudinal study in a tertiary care center was carried out. PATIENT SAMPLE The sample consisted of 276 patients who underwent lumbar surgery. OUTCOME MEASURES The Geriatric Depression Scale (GDS) and the Spielberger State-Trait Anxiety Inventory (STAI) were the outcome measures. METHODS Patients completed the following validated surveys several days before and again 2 years after surgery: the GDS with a set threshold for a positive screen for depression; the STAI with population norms used as threshold values; the Oswestry Disability Index (ODI); a numerical pain rating; and the Expectations Survey measuring amount of improvement expected. Dependent variables were pre- to postoperative within-patient change in GDS and STAI scores. Independent variables were three outcomes of surgery: proportion of expectations fulfilled, and changes in ODI scores and pain ratings. Analyses were conducted with GDS and STAI scores as continuous variables and according to threshold values, and for expectations, ODI and pain according to minimum clinically important differences (MCIDs). RESULTS Mean age was 55, 56% were men, and 78% had degenerative diagnoses. For depressive symptoms, 41% screened positive preoperatively and 16% screened positive postoperatively; 72% had some improvement. In multivariable analysis adjusted for age, gender, comorbidity, diagnosis, and surgical invasiveness, depressive symptoms improved more for more expectations fulfilled (p<.0001), more ODI improvement (p<.0001), and more pain improvement (p=.001). For anxiety symptoms: 59% were worse than population norms preoperatively and 26% were worse postoperatively; 73% had some improvement. In adjusted multivariable analyses, anxiety symptoms improved more for more expectations fulfilled (p=.0002), more ODI improvement (p<.0001), and more pain improvement (p=.03). Similar results were obtained according to threshold values and MCIDs. CONCLUSION Substantial improvements in psychological well-being resulted after surgery among patients with favorable spine-specific outcomes.

[1]  C. Mancuso,et al.  Physical and Psychological Comorbidity Independently Associated With Spine-Related Disability , 2014, Spine.

[2]  O. Airaksinen,et al.  Depressive Burden in the Preoperative and Early Recovery Phase Predicts Poorer Surgery Outcome Among Lumbar Spinal Stenosis Patients: A One-Year Prospective Follow-up Study , 2009, Spine.

[3]  C. Mancuso,et al.  Fulfillment of patients' expectations of lumbar and cervical spine surgery. , 2016, The spine journal : official journal of the North American Spine Society.

[4]  C. Mancuso,et al.  Proportion of Expectations Fulfilled: A New Method to Report Patient-centered Outcomes of Spine Surgery , 2016, Spine.

[5]  Joseph S. Cheng,et al.  Microdiscectomy improves pain-associated depression, somatic anxiety, and mental well-being in patients with herniated lumbar disc. , 2012 .

[6]  B. G. Rule,et al.  Reliability of the Geriatric Depression Scale for Younger Adults , 1990 .

[7]  V. Leirer,et al.  Development and validation of a geriatric depression screening scale: a preliminary report. , 1982, Journal of psychiatric research.

[8]  J. Farrar,et al.  Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale , 2001, PAIN.

[9]  M. Battié,et al.  Depression as a prognostic factor of lumbar spinal stenosis: a systematic review. , 2014, The spine journal : official journal of the North American Spine Society.

[10]  T. Mayer,et al.  Psychological Evaluation of the Spine Patient , 2008, The Journal of the American Academy of Orthopaedic Surgeons.

[11]  T. Mayer,et al.  Psychiatric Illness and Chronic Low-Back Pain: The Mind and the Spine—Which Goes First? , 1993, Spine.

[12]  D. Brodke,et al.  Clinical impression versus standardized questionnaire: the spinal surgeon's ability to assess psychological distress. , 2010, The Journal of bone and joint surgery. American volume.

[13]  C. Mancuso,et al.  Development and testing of an expectations survey for patients undergoing lumbar spine surgery. , 2013, The Journal of bone and joint surgery. American volume.

[14]  C. Mackenzie,et al.  A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. , 1987, Journal of chronic diseases.

[15]  Lorri A. Lee,et al.  Development of an Index to Characterize the “Invasiveness” of Spine Surgery: Validation by Comparison to Blood Loss and Operative Time , 2008, Spine.

[16]  M. McGirt,et al.  The impact of preoperative depression on quality of life outcomes after lumbar surgery. , 2014, The spine journal : official journal of the North American Spine Society.

[17]  P. Trief,et al.  A Prospective Study of Psychological Predictors of Lumbar Surgery Outcome , 2000, Spine.

[18]  P. Pynsent,et al.  The Oswestry Disability Index. , 2000, Spine.

[19]  S. Berven,et al.  Minimum clinically important difference in lumbar spine surgery patients: a choice of methods using the Oswestry Disability Index, Medical Outcomes Study questionnaire Short Form 36, and pain scales. , 2008, The spine journal : official journal of the North American Spine Society.

[20]  V. Neuhaus,et al.  Psychiatric Disorders and Major Spine Surgery: Epidemiology and Perioperative Outcomes , 2014, Spine.

[21]  J. Dekker,et al.  The prevalence of depressive symptoms before and after surgery and its association with disability in patients undergoing lumbar spinal fusion , 2013, European Spine Journal.

[22]  Joseph S. Cheng,et al.  Responsiveness of depression and its influence on surgical outcomes of lumbar degenerative diseases , 2015, European Journal of Orthopaedic Surgery & Traumatology.

[23]  J. Fairbank Revised Oswestry Disability questionnaire. , 2000, Spine.

[24]  C. Mancuso,et al.  Patients’ expectations of lumbar spine surgery , 2015, European Spine Journal.