Extremely Long-Range Chromatin Loops Link Topological Domains to Facilitate a Diverse Antibody Repertoire.

[1]  C. Benner,et al.  New roles for DNA cytosine modification, eRNA, anchors, and superanchors in developing B cell progenitors , 2015, Proceedings of the National Academy of Sciences.

[2]  Andrew S. Belmont,et al.  Large-scale chromatin organization: the good, the surprising, and the still perplexing. , 2014, Current opinion in cell biology.

[3]  A. Feeney,et al.  Flexible ordering of antibody class switch and V(D)J joining during B-cell ontogeny , 2013, Genes & development.

[4]  F. Alt,et al.  Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire. , 2013, Immunity.

[5]  Jennifer E. Phillips-Cremins,et al.  Architectural Protein Subclasses Shape 3D Organization of Genomes during Lineage Commitment , 2013, Cell.

[6]  Bas van Steensel,et al.  Genome Architecture: Domain Organization of Interphase Chromosomes , 2013, Cell.

[7]  J. Dekker,et al.  The hierarchy of the 3D genome. , 2013, Molecular cell.

[8]  P. Ferrier.  Faculty Opinions recommendation of Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate. , 2012 .

[9]  Bradley E. Bernstein,et al.  DNA Sequence-Dependent Compartmentalization and Silencing of Chromatin at the Nuclear Lamina , 2012, Cell.

[10]  J. Sedat,et al.  Spatial partitioning of the regulatory landscape of the X-inactivation centre , 2012, Nature.

[11]  Jesse R. Dixon,et al.  Topological Domains in Mammalian Genomes Identified by Analysis of Chromatin Interactions , 2012, Nature.

[12]  V. Seitan,et al.  Cohesin and chromatin organisation. , 2012, Current opinion in genetics & development.

[13]  Michael S. Becker,et al.  Spatial Organization of the Mouse Genome and Its Role in Recurrent Chromosomal Translocations , 2012, Cell.

[14]  Haiping Hao,et al.  Two Forms of Loops Generate the Chromatin Conformation of the Immunoglobulin Heavy-Chain Gene Locus , 2011, Cell.

[15]  F. Alt,et al.  CTCF Binding Elements Mediate Control of V(D)J Recombination , 2011, Nature.

[16]  Nicholas J. Schork,et al.  CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells , 2011, Proceedings of the National Academy of Sciences.

[17]  Maria Novatchkova,et al.  The distal V(H) gene cluster of the Igh locus contains distinct regulatory elements with Pax5 transcription factor-dependent activity in pro-B cells. , 2011, Immunity.

[18]  P. Flicek,et al.  Molecular maps of the reorganization of genome-nuclear lamina interactions during differentiation. , 2010, Molecular cell.

[19]  David G. Schatz,et al.  The In Vivo Pattern of Binding of RAG1 and RAG2 to Antigen Receptor Loci , 2010, Cell.

[20]  C. Murre.  Faculty Opinions recommendation of Cutting edge: developmental stage-specific recruitment of cohesin to CTCF sites throughout immunoglobulin loci during B lymphocyte development. , 2009 .

[21]  Dustin E. Schones,et al.  Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains. , 2008, Genome research.

[22]  Ignacio A. Demarco,et al.  Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros , 2008, Nature Immunology.

[23]  Tobias A. Knoch,et al.  The 3D Structure of the Immunoglobulin Heavy-Chain Locus: Implications for Long-Range Genomic Interactions , 2008, Cell.

[24]  K. Rajewsky,et al.  Yin Yang 1 is a critical regulator of B-cell development. , 2007, Genes & development.

[25]  J. Dekker,et al.  Mapping networks of physical interactions between genomic elements using 5C technology , 2007, Nature Protocols.

[26]  T. Pandita,et al.  ATM stabilizes DNA double-strand-break complexes during V(D)J recombination , 2006, Nature.

[27]  Colette M. Johnston,et al.  Complete Sequence Assembly and Characterization of the C57BL/6 Mouse Ig Heavy Chain V Region1 , 2006, The Journal of Immunology.

[28]  E. Oltz,et al.  Regulation of IgH Gene Assembly: Role of the Intronic Enhancer and 5′DQ52 Region in Targeting DHJH Recombination1 , 2006, The Journal of Immunology.

[29]  F. Alt,et al.  Elucidation of IgH intronic enhancer functions via germ-line deletion. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[30]  Roy Riblet,et al.  Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells. , 2005, Genes & development.

[31]  M. Busslinger,et al.  Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene. , 2004, Genes & development.

[32]  Roy Riblet,et al.  Subnuclear Compartmentalization of Immunoglobulin Loci During Lymphocyte Development , 2002, Science.

[33]  I. Amit,et al.  Comprehensive mapping of long-range interactions reveals folding principles of the human genome. , 2009, Science.

[34]  D. Schatz,et al.  Pax5 is required for recombination of transcribed, acetylated, 5' IgH V gene segments. , 2003, Genes & development.