Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Using an improved method of gel electrophoresis, many hitherto unknown proteins have been found in bacteriophage T4 and some of these have been identified with specific gene products. Four major components of the head are cleaved during the process of assembly, apparently after the precursor proteins have assembled into some large intermediate structure.

[1]  T. Minagawa Some characteristics of the internal protein phage T2. , 1961, Virology.

[2]  R. S. Edgar,et al.  Physiological Studies of Conditional Lethal Mutants of Bacteriophage T4D , 1963 .

[3]  S. Brenner,et al.  Co-Linearity of the Gene with the Polypeptide Chain , 1964, Nature.

[4]  B. Davis DISC ELECTROPHORESIS – II METHOD AND APPLICATION TO HUMAN SERUM PROTEINS * , 1964, Annals of the New York Academy of Sciences.

[5]  C. Levinthal,et al.  Analysis of C14-labeled proteins by disc electrophoresis. , 1965, Biochemical and biophysical research communications.

[6]  E. Kellenberger,et al.  Studies on the morphopoiesis of the head of phage T-even. I. Morphological, immunological, and genetic characterization of polyheads. , 1965, Journal of ultrastructure research.

[7]  S. Champe,et al.  Components in T4-infected cells associated with phage assembly. , 1966, Virology.

[8]  W. Wood,et al.  Morphogenesis of bacteriophage T4 in extracts of mutant-infected cells. , 1966, Proceedings of the National Academy of Sciences of the United States of America.

[9]  J V Maizel,et al.  Molecular weight estimation of polypeptide chains by electrophoresis in SDS-polyacrylamide gels. , 1967, Biochemical and biophysical research communications.

[10]  F. Eiserling,et al.  Studies on the morphopoiesis of the head of phage T-even. 3. The cores of head-related structures. , 1967, Journal of ultrastructure research.

[11]  C. Levinthal,et al.  Protein synthesis by Escherichia coli infected with bacteriophage T4D. , 1968, Virology.

[12]  J. King Assembly of the tau of bacteriophage T4 , 1968 .

[13]  E. Kellenberger Studies on the morphopoiesis of the head of phage T-even. V. The components of the T4 capsid and of other, capsid-related structures. , 1968, Virology.

[14]  Thomas A. Steitz,et al.  Structure of crystalline α-chymotrypsin: III. Crystallographic studies of substrates and inhibitors bound to the active site of α-chymotrypsin , 1969 .

[15]  K. Weber,et al.  The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis. , 1969, The Journal of biological chemistry.

[16]  U. K. Laemmli,et al.  A factor preventing the major head protein of bacteriophage T4 from random aggregation. , 1970, Journal of molecular biology.

[17]  P. Roslansky,et al.  Gel electrophoresis of the head proteins of T-even phage. , 1970, Virology.

[18]  L. Larcom,et al.  Subunits of T4 head structures. , 1970, Virology.

[19]  U. K. Laemmli,et al.  Form-determining function of the genes required for the assembly of the head of bacteriophage T4. , 1970, Journal of molecular biology.