Dysregulation of Blimp1 transcriptional repressor unleashes p130Cas/ErbB2 breast cancer invasion

[1]  W. Gradishar,et al.  Management of Metastatic HER2-Positive Breast Cancer: Where Are We and Where Do We Go From Here? , 2016, Oncology.

[2]  B. Illades-Aguiar,et al.  miR-23b as a potential tumor suppressor and its regulation by DNA methylation in cervical cancer , 2015, Infectious Agents and Cancer.

[3]  G. Inghirami,et al.  PRDM1/BLIMP1: a tumor suppressor gene in B and T cell lymphomas , 2015, Leukemia & lymphoma.

[4]  P. Casali,et al.  Histone Deacetylase Inhibitors Upregulate B Cell microRNAs That Silence AID and Blimp-1 Expression for Epigenetic Modulation of Antibody and Autoantibody Responses , 2014, The Journal of Immunology.

[5]  D. Schlaepfer,et al.  FAK in cancer: mechanistic findings and clinical applications , 2014, Nature Reviews Cancer.

[6]  M. Donadelli,et al.  Regulation of miR-23b expression and its dual role on ROS production and tumour development. , 2014, Cancer letters.

[7]  Kiyoji Nishiwaki,et al.  BLMP-1/Blimp-1 Regulates the Spatiotemporal Cell Migration Pattern in C. elegans , 2014, PLoS genetics.

[8]  N. Sang,et al.  ErbB2 Activation Upregulates Glutaminase 1 Expression Which Promotes Breast Cancer Cell Proliferation , 2014, Journal of cellular biochemistry.

[9]  F. Orso,et al.  Identification of p130Cas/ErbB2-dependent invasive signatures in transformed mammary epithelial cells , 2013, Cell cycle.

[10]  Andrea Sottoriva,et al.  The shaping and functional consequences of the microRNA landscape in breast cancer , 2013, Nature.

[11]  George A Calin,et al.  Prooncogenic factors miR-23b and miR-27b are regulated by Her2/Neu, EGF, and TNF-α in breast cancer. , 2013, Cancer research.

[12]  M. Periyasamy,et al.  miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts , 2013, Nucleic acids research.

[13]  P. Frankel,et al.  p130Cas: a key signalling node in health and disease. , 2013, Cellular signalling.

[14]  D. Allred,et al.  Loss of Par3 promotes breast cancer metastasis by compromising cell–cell cohesion , 2012, Nature Cell Biology.

[15]  D. Seldin,et al.  Epithelial-to-mesenchymal transition induced by TGF-β1 is mediated by Blimp-1-dependent repression of BMP-5. , 2012, Cancer research.

[16]  Data production leads,et al.  An integrated encyclopedia of DNA elements in the human genome , 2012 .

[17]  T. Naoe,et al.  B Cell Receptor-ERK1/2 Signal Cancels PAX5-Dependent Repression of BLIMP1 through PAX5 Phosphorylation: A Mechanism of Antigen-Triggering Plasma Cell Differentiation , 2012, The Journal of Immunology.

[18]  F. Markowetz,et al.  The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups , 2012, Nature.

[19]  G. Sonenshein,et al.  Blimp1 Activation by AP-1 in Human Lung Cancer Cells Promotes a Migratory Phenotype and Is Inhibited by the Lysyl Oxidase Propeptide , 2012, PloS one.

[20]  M. McNiven,et al.  Invasive matrix degradation at focal adhesions occurs via protease recruitment by a FAK–p130Cas complex , 2012, The Journal of cell biology.

[21]  Martin Renqiang Min,et al.  An integrated encyclopedia of DNA elements in the human genome , 2012 .

[22]  Changhong Sun,et al.  Genome-wide functional screening of miR-23b as a pleiotropic modulator suppressing cancer metastasis. , 2011, Nature communications.

[23]  K. Karube,et al.  Identification of FOXO3 and PRDM1 as tumor-suppressor gene candidates in NK-cell neoplasms by genomic and functional analyses. , 2011, Blood.

[24]  P. Provero,et al.  p130Cas promotes invasiveness of three-dimensional ErbB2-transformed mammary acinar structures by enhanced activation of mTOR/p70S6K and Rac1. , 2011, European journal of cell biology.

[25]  Xavier Robin,et al.  pROC: an open-source package for R and S+ to analyze and compare ROC curves , 2011, BMC Bioinformatics.

[26]  P. Defilippi,et al.  Integrin signalling adaptors: not only figurants in the cancer story , 2010, Nature Reviews Cancer.

[27]  G. Forni,et al.  p130Cas is an essential transducer element in ErbB2 transformation , 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[28]  Trevor Hastie,et al.  Regularization Paths for Generalized Linear Models via Coordinate Descent. , 2010, Journal of statistical software.

[29]  E. Golemis,et al.  CAS proteins in normal and pathological cell growth control , 2010, Cellular and Molecular Life Sciences.

[30]  R. Welsh Blimp hovers over T cell immunity. , 2009, Immunity.

[31]  S. Nutt,et al.  Blimp-1 transcription factor is required for the differentiation of effector CD8(+) T cells and memory responses. , 2009, Immunity.

[32]  G. Shukla,et al.  Intrinsic expression of host genes and intronic miRNAs in prostate carcinoma cells , 2009, Cancer Cell International.

[33]  V. Trinkaus-Randall,et al.  RelB NF-κB Represses Estrogen Receptor α Expression via Induction of the Zinc Finger Protein Blimp1 , 2009, Molecular and Cellular Biology.

[34]  L. Garrett-Sinha,et al.  Blimp1: a conserved transcriptional repressor critical for differentiation of many tissues. , 2009, Experimental cell research.

[35]  T. Tuschl,et al.  Tumorigenesis and Neoplastic Progression MicroRNA-Mediated Down-Regulation of PRDM 1 / Blimp-1 in Hodgkin / Reed-Sternberg Cells : A Potential Pathogenetic Lesion in Hodgkin Lymphomas , 2010 .

[36]  A. Canutescu,et al.  A novel Cas family member, HEPL, regulates FAK and cell spreading. , 2008, Molecular biology of the cell.

[37]  K. Fairfax,et al.  BLIMP1 guides the fate of effector B and T cells , 2007, Nature Reviews Immunology.

[38]  M. Moasser The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis , 2007, Oncogene.

[39]  Paola Defilippi,et al.  p130Cas: a versatile scaffold in signaling networks. , 2006, Trends in cell biology.

[40]  A. Sapino,et al.  p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis. , 2006, Cancer research.

[41]  T. Wilm,et al.  Essential roles of a zebrafish prdm1/blimp1 homolog in embryo patterning and organogenesis , 2005, Development.

[42]  D. A. Hanson,et al.  Focal adhesion kinase: in command and control of cell motility , 2005, Nature Reviews Molecular Cell Biology.

[43]  A. Sandelin,et al.  Applied bioinformatics for the identification of regulatory elements , 2004, Nature Reviews Genetics.

[44]  Joshua LaBaer,et al.  Cooperation of the ErbB2 receptor and transforming growth factor beta in induction of migration and invasion in mammary epithelial cells. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[45]  Donna J. Webb,et al.  FAK–Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly , 2004, Nature Cell Biology.

[46]  A. Bookout,et al.  Quantitative real-time PCR protocol for analysis of nuclear receptor signaling pathways , 2003, Nuclear receptor signaling.

[47]  Tom H. Pringle,et al.  The human genome browser at UCSC. , 2002, Genome research.

[48]  M. Bissell,et al.  ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini , 2001, Nature Cell Biology.

[49]  D. Schlaepfer,et al.  Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration. , 1999, Journal of cell science.

[50]  M. J. van de Vijver,et al.  Neu-protein overexpression in breast cancer. Association with comedo-type ductal carcinoma in situ and limited prognostic value in stage II breast cancer. , 1988, The New England journal of medicine.