Spatial intensity distribution analysis (SpIDA): a new tool for receptor tyrosine kinase activation and transactivation quantification.

[1]  Mikhail Sergeev,et al.  Determination of Membrane Protein Transporter Oligomerization in Native Tissue Using Spatial Fluorescence Intensity Fluctuation Analysis , 2012, PloS one.

[2]  Mikhail Sergeev,et al.  Ligand-induced clustering of EGF receptors: a quantitative study by fluorescence image moment analysis. , 2012, Biophysical chemistry.

[3]  Yves De Koninck,et al.  Efficacy of Synaptic Inhibition Depends on Multiple, Dynamically Interacting Mechanisms Implicated in Chloride Homeostasis , 2011, PLoS Comput. Biol..

[4]  Y. de Koninck,et al.  Revealing protein oligomerization and densities in situ using spatial intensity distribution analysis , 2011, Proceedings of the National Academy of Sciences.

[5]  Y. de Koninck,et al.  Quantification of receptor tyrosine kinase transactivation through direct dimerization and surface density measurements in single cells , 2011, Proceedings of the National Academy of Sciences.

[6]  L. Luttrell,et al.  Beyond Desensitization: Physiological Relevance of Arrestin-Dependent Signaling , 2010, Pharmacological Reviews.

[7]  J. Beaulieu,et al.  Confocal Analysis of Cholinergic and Dopaminergic Inputs onto Pyramidal Cells in the Prefrontal Cortex of Rodents , 2010, Front. Neuroanat..

[8]  C. Tautermann,et al.  G-protein-coupled receptor-focused drug discovery using a target class platform approach. , 2009, Drug discovery today.

[9]  R. Gainetdinov,et al.  Antagonism of dopamine D2 receptor/β-arrestin 2 interaction is a common property of clinically effective antipsychotics , 2008, Proceedings of the National Academy of Sciences.

[10]  B. Gloss,et al.  Drd1a-tdTomato BAC Transgenic Mice for Simultaneous Visualization of Medium Spiny Neurons in the Direct and Indirect Pathways of the Basal Ganglia , 2008, The Journal of Neuroscience.

[11]  A. Salahpour,et al.  Experimental challenge to a 'rigorous' BRET analysis of GPCR oligomerization , 2007, Nature Methods.

[12]  L. Prézeau,et al.  Real-Time Analysis of Agonist-Induced Activation of Protease-Activated Receptor 1/Gαi1 Protein Complex Measured by Bioluminescence Resonance Energy Transfer in Living Cells , 2007, Molecular Pharmacology.

[13]  M. Caron,et al.  β-Arrestin Goes Nuclear , 2005, Cell.

[14]  F. Lee,et al.  Transactivation of Trk Neurotrophin Receptors by G-Protein-Coupled Receptor Ligands Occurs on Intracellular Membranes , 2004, The Journal of Neuroscience.

[15]  Terrence P. Kenakin,et al.  A Pharmacology Primer: Theory, Application and Methods , 2004 .

[16]  R. Tsien,et al.  Partitioning of Lipid-Modified Monomeric GFPs into Membrane Microdomains of Live Cells , 2002, Science.

[17]  S. Ferguson,et al.  Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. , 2001, Pharmacological reviews.

[18]  J. Schlessinger,et al.  Cell Signaling by Receptor Tyrosine Kinases , 2000, Cell.

[19]  E Gratton,et al.  The photon counting histogram in fluorescence fluctuation spectroscopy. , 1999, Biophysical journal.

[20]  T M Jovin,et al.  Comparison of fixation protocols for adherent cultured cells applied to a GFP fusion protein of the epidermal growth factor receptor. , 1999, Cytometry.

[21]  H. Kawakatsu,et al.  Calcium-dependent Epidermal Growth Factor Receptor Transactivation Mediates the Angiotensin II-induced Mitogen-activated Protein Kinase Activation in Vascular Smooth Muscle Cells* , 1998, The Journal of Biological Chemistry.

[22]  A. Levitzki,et al.  Tyrosine kinase inhibition: an approach to drug development. , 1995, Science.

[23]  P. Stahl,et al.  Structure-function relationship of the small GTPase rab5. , 1993, The Journal of biological chemistry.

[24]  Kai Simons,et al.  The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway , 1992, Cell.

[25]  E. Rozengurt,et al.  Phorbol esters and vasopressin stimulate DNA synthesis by a common mechanism , 1980, Nature.

[26]  D. Sheff,et al.  Immunostaining: detection of signaling protein location in tissues, cells and subcellular compartments. , 2013, Methods in cell biology.

[27]  Y. de Koninck,et al.  Quantification of receptor tyrosine kinase activation and transactivation by G-protein-coupled receptors using spatial intensity distribution analysis (SpIDA). , 2013, Methods in enzymology.

[28]  B. Berk,et al.  Crosstalk coregulation mechanisms of G protein-coupled receptors and receptor tyrosine kinases. , 2006, Methods in molecular biology.

[29]  G. Kondoh Development of glycosylphosphatidylinositol-anchored enhanced green fluorescent protein. One-step visualization of GPI fate in global tissues and ubiquitous cell surface marking. , 2002, Methods in molecular biology.

[30]  A. Ullrich,et al.  Growth factor receptor tyrosine kinases. , 1988, Annual review of biochemistry.

[31]  A. Gilman,et al.  G proteins: transducers of receptor-generated signals. , 1987, Annual review of biochemistry.