Maternal and Neonatal Outcomes After Attempted Suicide

OBJECTIVE: The purpose of this study was to describe identifiers and estimate maternal and neonatal outcomes in women who attempt suicide during pregnancy. METHODS: A linked Vital Statistics-Patient Discharge database of the State of California was used to identify cases of intentional injury during pregnancy. A retrospective analysis of maternal and neonatal outcomes in pregnant women who were admitted for attempted suicide is presented. RESULTS: There were 4,833,286 deliveries in California from 1991 to 1999. Of those deliveries, 2,132 were complicated by attempted suicide during pregnancy (0.4 per 1,000 pregnancies). The control population was composed of patients who did not attempt suicide. The group of women that attempted suicide during pregnancy had increases in premature labor, cesarean delivery, and need for blood transfusion. Analysis of neonatal outcomes revealed increases in respiratory distress syndrome and low birth weight infants. A subanalysis, including women who delivered at the hospitalization for attempted suicide, demonstrated increased premature delivery, respiratory distress syndrome, and neonatal and infant death. CONCLUSION: Attempted suicide is associated with significantly higher rates of maternal and perinatal morbidity, and in some cases, perinatal mortality. The best identifier for women at risk for attempting suicide is substance abuse. Care provider identification and prevention are of key importance in preventing these outcomes. LEVEL OF EVIDENCE: II-2

[1]  A. Czeizel,et al.  Teratologic Evaluation of 178 Infants Born to Mothers Who Attempted Suicide by Drugs During Pregnancy , 1997, Obstetrics and gynecology.

[2]  S. Zubrick,et al.  Pregnancy, delivery, and neonatal complications in a population cohort of women with schizophrenia and major affective disorders. , 2005, The American journal of psychiatry.

[3]  L. Appleby,et al.  Suicide during pregnancy and in the first postnatal year. , 1991, BMJ.

[4]  D. Zatzick,et al.  Chart-recorded psychiatric diagnoses in women giving birth in California in 1992. , 1999, The American journal of psychiatry.

[5]  I. Gotlib,et al.  Prevalence rates and demographic characteristics associated with depression in pregnancy and the postpartum. , 1989, Journal of consulting and clinical psychology.

[6]  D. Diamond,et al.  Maternal predictors of fetal demise in trauma during pregnancy. , 1991, Surgery, gynecology & obstetrics.

[7]  D. Hoyt,et al.  Trauma in pregnancy: maternal and fetal outcomes. , 1998, The Journal of trauma.

[8]  H B Weiss,et al.  Fetal deaths related to maternal injury. , 2001, JAMA.

[9]  T S Nesbitt,et al.  Vital statistics linked birth/infant death and hospital discharge record linkage for epidemiological studies. , 1997, Computers and biomedical research, an international journal.

[10]  G. Koren,et al.  Perinatal outcome following third trimester exposure to paroxetine. , 2002, Archives of pediatrics & adolescent medicine.

[11]  J. Lonnqvist,et al.  Suicides after pregnancy in Finland, 1987–94: register linkage study , 1996, BMJ.

[12]  L. Hankoff Reducing Suicide: A National Imperative , 2003 .

[13]  J. Dayan,et al.  Role of anxiety and depression in the onset of spontaneous preterm labor. , 2002, American journal of epidemiology.

[14]  Ronald C Kessler,et al.  Trends in suicide ideation, plans, gestures, and attempts in the United States, 1990-1992 to 2001-2003. , 2005, JAMA.

[15]  M. O’Hara Social support, life events, and depression during pregnancy and the puerperium. , 1986, Archives of general psychiatry.

[16]  M. Hedegaard,et al.  Psychological distress in pregnancy and preterm delivery , 1994 .

[17]  M. Knudson,et al.  Profile of mothers at risk: an analysis of injury and pregnancy loss in 1,195 trauma patients. , 2005, Journal of the American College of Surgeons.

[18]  S. Hoffman,et al.  Depressive symptomatology during pregnancy: evidence for an association with decreased fetal growth in pregnancies of lower social class women. , 2000, Health psychology : official journal of the Division of Health Psychology, American Psychological Association.

[19]  S. James,et al.  Maternal prenatal depressive symptoms and spontaneous preterm births among African-American women in Baltimore, Maryland. , 2002, American journal of epidemiology.

[20]  R. Steer,et al.  Self-reported depression and negative pregnancy outcomes. , 1992, Journal of clinical epidemiology.

[21]  B. Källén Neonate characteristics after maternal use of antidepressants in late pregnancy. , 2004, Archives of pediatrics & adolescent medicine.

[22]  J. Olsen,et al.  Pregnancy outcome after suicide attempt by drug use: a Danish population‐based study , 2002, Acta obstetricia et gynecologica Scandinavica.

[23]  J K Williams,et al.  Evaluation of Blunt Abdominal Trauma in the Third Trimester of Pregnancy: Maternal and Fetal Considerations , 1990, Obstetrics and gynecology.

[24]  A. Leon,et al.  Lower risk of suicide during pregnancy. , 1997, The American journal of psychiatry.