Quality of life in cirrhotic patients and liver transplant recipients

This study analyses the health related quality of life in patients diagnosed with hepatic cirrhosis (HC) in the three Child-Pugh stages (A, B and C) and in liver transplant recipients (OLT). Health related quality of life was quantified by the multidimensional psychometric test PLC (Siegrits, Boer and Junge, 1996). In general, patients HC and OLT had a poorer scores than the control group in Physical Wellbeing, Physical Function, Positive Mood, Negative Mood and Psychological Wellbeing scales. Also, patients with OLT present a better quality of life than patients with advanced cirrhosis (Child B and C) in scales that evaluate Physical, Psychological and Social functions. The OLT group even obtained higher scores in the Positive Mood scale than Child-A cirrhotics. Our results suggest that although quality of life in OLT patients does not reach levels of healthy individuals, it is significantly better than in cirrhotic patients, especially than those in advanced stages. Calidad de vida en pacientes cirroticos y trasplantados hepaticos. Este estudio analiza la calidad de vida relacionada con la salud en pacientes diagnosticados de cirrosis hepatica (CH) en los tres estadios Child-Pugh (A, B y C) y en pacientes trasplantados (OLT). La calidad de vida ha sido cuantificada por la prueba psicometrica multidimensional PLC (Siegrits, Boer and Junge, 1996). En general, los pacientes CH y OLT presentaron peores puntuaciones que el grupo control en las dimensiones de Capacidad fisica, Funcion fisica, Animo positivo, Animo negativo y Bienestar psicologico. Aunque los pacientes OLT mostraron mejor calidad de vida que los pacientes con estados avanzados de cirrosis (Child B y C) en las escalas que evaluan las funciones fisica, psicologica y social. El grupo OLT presentan puntuaciones mas altas en la dimension Animo positivo respecto al grupo de pacientes cirroticos en estadio Child A. Nuestros resultados sugieren que la calidad de vida en pacientes OLT no alcanza los niveles de la poblacion sana, pero es significativamente mejor que en pacientes CH especialmente en fases avanzadas.

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