Divergent metabolic phenotypes in two genetic syndromes of low insulin secretion.

[1]  J. Guevara-Aguirre,et al.  IGF-I deficiency and enhanced insulin sensitivity due to a mutated growth hormone receptor gene in humans , 2020, Molecular and Cellular Endocrinology.

[2]  J. Guevara-Aguirre,et al.  Insights from the clinical phenotype of subjects with Laron syndrome in Ecuador , 2020, Reviews in Endocrine and Metabolic Disorders.

[3]  A. Besson,et al.  Functional Versatility of the CDK Inhibitor p57Kip2 , 2020, Frontiers in Cell and Developmental Biology.

[4]  H. Werner,et al.  Laron syndrome – A historical perspective , 2020, Reviews in Endocrine and Metabolic Disorders.

[5]  J. Guevara-Aguirre,et al.  Assessing insulin sensitivity and resistance in syndromes of severe short stature. , 2020, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

[6]  J. Guevara-Aguirre,et al.  GH and GHR signaling in human disease. , 2017, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

[7]  J. Guevara-Aguirre,et al.  Insulin resistance depends on GH counter-regulation in two syndromes of short stature. , 2017, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

[8]  M. Bugliani,et al.  Pancreatic Beta Cell Identity in Humans and the Role of Type 2 Diabetes , 2017, Front. Cell Dev. Biol..

[9]  M. Maghnie,et al.  Diagnosis and management of Silver–Russell syndrome: first international consensus statement , 2017, Nature Reviews Endocrinology.

[10]  S. Kwak,et al.  10-year trajectory of β-cell function and insulin sensitivity in the development of type 2 diabetes: a community-based prospective cohort study. , 2016, The lancet. Diabetes & endocrinology.

[11]  M. Polak,et al.  Mutations of the Imprinted CDKN1C Gene as a Cause of the Overgrowth Beckwith–Wiedemann Syndrome: Clinical Spectrum and Functional Characterization , 2015, Human mutation.

[12]  R. de Cabo,et al.  GH Receptor Deficiency in Ecuadorian Adults Is Associated With Obesity and Enhanced Insulin Sensitivity. , 2015, The Journal of clinical endocrinology and metabolism.

[13]  Leslie S Satin,et al.  Pulsatile insulin secretion, impaired glucose tolerance and type 2 diabetes. , 2015, Molecular aspects of medicine.

[14]  G. Rutter,et al.  Pancreatic β-cell identity, glucose sensing and the control of insulin secretion. , 2015, The Biochemical journal.

[15]  A. Bagchi,et al.  Insulin resistance: an additional risk factor in the pathogenesis of cardiovascular disease in type 2 diabetes , 2015, Heart Failure Reviews.

[16]  Michael H. Guo,et al.  A novel variant in CDKN1C is associated with intrauterine growth restriction, short stature, and early-adulthood-onset diabetes. , 2014, The Journal of clinical endocrinology and metabolism.

[17]  J. Guevara-Aguirre,et al.  Obesity, diabetes and cancer: insight into the relationship from a cohort with growth hormone receptor deficiency , 2014, Diabetologia.

[18]  G. Rossi Diagnosis and Classification of Diabetes Mellitus , 2011, Diabetes Care.

[19]  S. Nelson,et al.  Mutations in the PCNA-binding domain of CDKN1C cause IMAGE Syndrome , 2012, Nature Genetics.

[20]  H. Ostrer,et al.  Intrauterine and postnatal growth failure with normal GH/IGF1 axis and insulin-resistant diabetes in a consanguineous kinship. , 2012, European journal of endocrinology.

[21]  Per Westermark,et al.  Islet amyloid polypeptide, islet amyloid, and diabetes mellitus. , 2011, Physiological reviews.

[22]  Federica Madia,et al.  Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-Aging Signaling, Cancer, and Diabetes in Humans , 2011, Science Translational Medicine.

[23]  M. Karaca,et al.  Functional pancreatic beta-cell mass: involvement in type 2 diabetes and therapeutic intervention. , 2009, Diabetes & metabolism.

[24]  R. Muniyappa,et al.  Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage. , 2008, American journal of physiology. Endocrinology and metabolism.

[25]  P. Lapunzina,et al.  Familial occurrence of the IMAGe association: additional clinical variants and a proposed mode of inheritance. , 2005, The Journal of clinical endocrinology and metabolism.

[26]  M. Lipsett,et al.  Disruption of growth hormone receptor gene causes diminished pancreatic islet size and increased insulin sensitivity in mice. , 2004, American journal of physiology. Endocrinology and metabolism.

[27]  L. Groop,et al.  Insulin resistance and insulin deficiency in the pathogenesis of Type 2 (non-insulin-dependent) diabetes mellitus: errors of metabolism or of methods? , 1993, Diabetologia.

[28]  Andrea Tura,et al.  Assessing insulin secretion by modeling in multiple-meal tests: role of potentiation. , 2002, Diabetes.

[29]  L. Miller,et al.  Glucose and forskolin regulate IAPP gene expression through different signal transduction pathways. , 2001, American journal of physiology. Endocrinology and metabolism.

[30]  K. Polonsky,et al.  Interactions between insulin resistance and insulin secretion in the development of glucose intolerance. , 2000, The Journal of clinical investigation.

[31]  A. King,et al.  Hypoglycemia in Beckwith-Wiedemann syndrome. , 2000, Seminars in perinatology.

[32]  M. Kay,et al.  IMAGe, a new clinical association of intrauterine growth retardation, metaphyseal dysplasia, adrenal hypoplasia congenita, and genital anomalies. , 1999, The Journal of clinical endocrinology and metabolism.

[33]  C. Bogardus,et al.  The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. , 1999, The Journal of clinical investigation.

[34]  J. Guevara-Aguirre,et al.  Growth hormone (GH) insensitivity due to primary GH receptor deficiency. , 1994, Endocrine reviews.

[35]  U. Francke,et al.  Mutation creating a new splice site in the growth hormone receptor genes of 37 Ecuadorean patients with Laron syndrome , 1992, Human mutation.

[36]  R. DeFronzo,et al.  Insulin Resistance: A Multifaceted Syndrome Responsible for NIDDM, Obesity, Hypertension, Dyslipidemia, and Atherosclerotic Cardiovascular Disease , 1991, Diabetes Care.

[37]  G. Reaven Role of Insulin Resistance in Human Disease , 1988, Diabetes.

[38]  R. DeFronzo,et al.  Glucose clamp technique: a method for quantifying insulin secretion and resistance. , 1979, The American journal of physiology.

[39]  A. Pertzelan,et al.  Genetic pituitary dwarfism with high serum concentation of growth hormone--a new inborn error of metabolism? , 1966, Israel journal of medical sciences.