Caspase-3-like proteases and 6-hydroxydopamine induced neuronal cell death.

[1]  Y. Lazebnik,et al.  Caspases: enemies within. , 1998, Science.

[2]  S. Paul,et al.  Peptide inhibitors of caspase-3-like proteases attenuate MPP+ -induced toxicity of cultured fetal rat mesencephalic dopamine neurons , 1998, Neuroscience.

[3]  C. Borner,et al.  Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c , 1998, Nature.

[4]  Sten Orrenius,et al.  Injected cytochrome c induces apoptosis , 1998, Nature.

[5]  S. Nagata,et al.  A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD , 1998, Nature.

[6]  M. V. Heiden,et al.  Bcl-xL Regulates the Membrane Potential and Volume Homeostasis of Mitochondria , 1997, Cell.

[7]  John Calvin Reed,et al.  Cytochrome c: Can't Live with It—Can't Live without It , 1997, Cell.

[8]  S. Srinivasula,et al.  Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade , 1997, Cell.

[9]  G. Salvesen,et al.  Caspases: Intracellular Signaling by Proteolysis , 1997, Cell.

[10]  S. Korsmeyer,et al.  Bax Deletion Further Orders the Cell Death Pathway in Cerebellar Granule Cells and Suggests a Caspase-independent Pathway to Cell Death , 1997, The Journal of cell biology.

[11]  S. Paul,et al.  Involvement of a Caspase‐3‐Like Cysteine Protease in 1‐Methyl‐4‐Phenylpyridinium‐Mediated Apoptosis of Cultured Cerebellar Granule Neurons , 1997, Journal of neurochemistry.

[12]  W. Cass,et al.  GDNF Protection against 6-OHDA: Time Dependence and Requirement for Protein Synthesis , 1997, The Journal of Neuroscience.

[13]  A. Yakovlev,et al.  The Role of CED-3-Related Cysteine Proteases in Apoptosis of Cerebellar Granule Cells , 1997, The Journal of Neuroscience.

[14]  Xiaodong Wang,et al.  Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3 , 1997, Cell.

[15]  N. Thornberry,et al.  Caspases: killer proteases. , 1997, Trends in biochemical sciences.

[16]  N. Thornberry,et al.  A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B , 1997, The Journal of Biological Chemistry.

[17]  A. Napolitano,et al.  Iron-mediated generation of the neurotoxin 6-hydroxydopamine quinone by reaction of fatty acid hydroperoxides with dopamine: a possible contributory mechanism for neuronal degeneration in Parkinson's disease. , 1997, Journal of medicinal chemistry.

[18]  Xiaodong Wang,et al.  DFF, a Heterodimeric Protein That Functions Downstream of Caspase-3 to Trigger DNA Fragmentation during Apoptosis , 1997, Cell.

[19]  K. Wilson,et al.  Substrate and Inhibitor Specificity of Interleukin-1β-converting Enzyme and Related Caspases* , 1997, The Journal of Biological Chemistry.

[20]  S. Paul,et al.  Cloning and Expression of a Rat Brain Interleukin-1β-Converting Enzyme (ICE)-Related Protease (IRP) and Its Possible Role in Apoptosis of Cultured Cerebellar Granule Neurons , 1997, The Journal of Neuroscience.

[21]  Dean P. Jones,et al.  Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked , 1997, Science.

[22]  J.-G. Chang,et al.  Molecular analysis of survival motor neuron (SMN) and neuronal apoptosis inhibitory protein (NAIP) genes of spinal muscular atrophy patients and their parents , 1997, Human Genetics.

[23]  A. Rosen,et al.  Macromolecular substrates for the ICE‐like proteases during apoptosis , 1997, Journal of cellular biochemistry.

[24]  J. Xiang,et al.  BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[25]  T. Miller,et al.  Metabolic and Genetic Analyses of Apoptosis in Potassium/Serum-Deprived Rat Cerebellar Granule Cells , 1996, The Journal of Neuroscience.

[26]  Keisuke Kuida,et al.  Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice , 1996, Nature.

[27]  C. Cotman,et al.  Mechanisms of Neuronal Death in Alzheimer's Disease , 1996, Brain pathology.

[28]  M. Hayden,et al.  Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract , 1996, Nature Genetics.

[29]  M. Weller,et al.  Potassium Deprivation-Induced Apoptosis of Cerebellar Granule Neurons: A Sequential Requirement for New mRNA and Protein Synthesis, ICE-Like Protease Activity, and Reactive Oxygen Species , 1996, The Journal of Neuroscience.

[30]  P. Carvey,et al.  Loss of Striatal DA Innervation Increases Striatal Trophic Activity Directed at DA Neurons in Culture , 1996, Experimental Neurology.

[31]  Xiaodong Wang,et al.  Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c , 1996, Cell.

[32]  K. Tipton,et al.  Nature of Inhibition of Mitochondrial Respiratory Complex I by 6‐Hydroxydopamine , 1996, Journal of neurochemistry.

[33]  Y. Lazebnik,et al.  Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[34]  Patrick R. Griffin,et al.  Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis , 1995, Nature.

[35]  A. K. Agarwal,et al.  Free Radical‐Generated Neurotoxicity of 6‐Hydroxydopamine , 1995, Journal of neurochemistry.

[36]  M. Youdim,et al.  Inhibition of mitochondrial complexes I and IV by 6-hydroxydopamine. , 1995, European journal of pharmacology.

[37]  R. Kamen,et al.  Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock , 1995, Cell.

[38]  C. Waters,et al.  Neurotoxin-induced cell death in neuronal PC12 cells is mediated by induction of apoptosis , 1994, Neuroscience.

[39]  M. Weller,et al.  Depolarization or glutamate receptor activation blocks apoptotic cell death of cultured cerebellar granule neurons , 1994, Brain Research.

[40]  S. D’Mello,et al.  Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[41]  J. Luthman,et al.  Structural and neurochemical effects in mouse cerebellum following neonatal methylazoxymethanol and 6-hydroxydopamine treatment , 1990, International Journal of Developmental Neuroscience.

[42]  A. Marini,et al.  The neurotoxicity of 1-methyl-4-phenylpyridinium in cultured cerebellar granule cells , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[43]  A. Guidotti,et al.  The activation of inositol phospholipid metabolism as a signal- transducing system for excitatory amino acids in primary cultures of cerebellar granule cells , 1986, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[44]  T. Berger,et al.  Effects of intraventricular 6-hydroxydopamine on the dopaminergic innervation of striatum: Histochemical and neurochemical analysis , 1986, Brain Research.

[45]  M. Berry,et al.  Selective destruction of meningeal cells by 6-hydroxydopamine: a tool to study meningeal-neuroepithelial interaction in brain development. , 1985, Developmental biology.

[46]  D. Jacobowitz,et al.  Pharmacological actions of 6-hydroxydopamine. , 1974, Pharmacological reviews.

[47]  Y. Agid,et al.  Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease. , 1997, Histology and histopathology.

[48]  E. Zamrini,et al.  Apoptotic-like changes in Lewy-body-associated disorders and normal aging in substantia nigral neurons. , 1997, The American journal of pathology.

[49]  M. Youdim,et al.  Mechanism of 6-hydroxydopamine neurotoxicity. , 1997, Journal of neural transmission. Supplementum.

[50]  K. Jellinger,et al.  Chemical evidence for 6-hydroxydopamine to be an endogenous toxic factor in the pathogenesis of Parkinson's disease. , 1995, Journal of neural transmission. Supplementum.

[51]  H. Lorenz,et al.  A rapid and simple method for the isolation of apoptotic DNA fragments. , 1994, Nucleic acids research.

[52]  R. Oppenheim.  Cell death during development of the nervous system. , 1991, Annual review of neuroscience.

[53]  A. Guidotti,et al.  Glutamate-induced neuronal death in primary cultures of cerebellar granule cells: protection by synthetic derivatives of endogenous sphingolipids. , 1990, The Journal of pharmacology and experimental therapeutics.

[54]  A. Barrett.  [42] Cathepsin G , 1981 .

[55]  C. Sachs,et al.  Mechanisms of action of 6-hydroxydopamine. , 1975, Biochemical Pharmacology.