Biological activities of dihydrodiols derived from two polycyclic hydrocarbons in rodent test systems.

[1]  H. Marquardt,et al.  Induction of malignant transformation and mutagenesis by dihydrodiols derived from 7,12-dimethylbenz[a]anthracene. , 1978, Biochemical and biophysical research communications.

[2]  H. Bartsch,et al.  Microsome-mediated mutagenicities of the dihydrodiols of 7,12-dimethylbenz[a]anthracene: high mutagenic activity of the 3,4-dihydrodiol. , 1978, Biochemical and biophysical research communications.

[3]  C. Walsh,et al.  The preparation of dihydrodiols from 7-methylbenz[a]-anthracene. , 1978, Chemico-biological interactions.

[4]  A. Dipple,et al.  Differences between products of binding of 7,12-dimethylbenz[a]anthracene to DNA in mouse skin and in a rat liver microsomal system. , 1978, Biochemical and Biophysical Research Communications - BBRC.

[5]  C. Harris,et al.  Structures of benzo(a)pyrene–nucleic acid adducts formed in human and bovine bronchial explants , 1977, Nature.

[6]  C. Walsh,et al.  The metabolic activation of 7-methylbenz(a)anthracene in mouse skin. , 1977, Chemico-biological interactions.

[7]  P. Sims,et al.  The metabolic activation of 7‐methylbenz(a)anthracene: The induction of malignant transformation and mutation in mammalian cells by non‐K‐region dihydrodiols , 1977, International journal of cancer.

[8]  P. Vigny,et al.  Metabolic activation of polycyclic hydrocarbons Fluorescence spectral evidence is consistent with metabolism at the 1,2‐ and 3,4‐double bonds of 7‐methylbenz[a]anthracene , 1977, FEBS letters.

[9]  P. Grover,et al.  The metabolic activation of 7-methylbenz(a)anthracene in mouse skin: High tumour-initiating activity of the 3,4-dihydrodiol , 1977 .

[10]  D. Jerina,et al.  (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo (a)pyrene: a potent skin carcinogen when applied topically to mice. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[11]  T. Slaga,et al.  Skin tumor initiating ability of benzo(a)pyrene 4,5- 7,5- and 7,8-diol-9,10-epoxides and 7,8-diol. , 1976, Cancer letters.

[12]  P. Grover,et al.  Tumour-initiating activities on mouse skin of dihydrodiols derived from benzo[a]pyrene. , 1976, British Journal of Cancer.

[13]  A. Y. Lu,et al.  Mutagenicity of metabolically activated benzo[a]anthracene 3,4-dihydrodiol: evidence for bay region activation of carcinogenic polycyclic hydrocarbons. , 1976, Biochemical and biophysical research communications.

[14]  A. Hewer,et al.  The involvement of a diol‐epoxide in the metabolic activation of benzo(a)pyrene in human bronchial mucosa and in mouse skin , 1976, International journal of cancer.

[15]  H. Marquardt,et al.  In vitro malignant transformation of mouse fibroblasts by non-K-region dihydrodiols derived from 7-methylbenz(a)anthracene, 7,12-dimethylbenz(a)anthracene, and benzo(a)pyrene. , 1976, Cancer research.

[16]  H. Bartsch,et al.  Mutagenicity of non-K-region diols and diol-epoxides of benz(a)anthracene and benzo(a)pyrene in S. typhimurium TA 100. , 1975, Biochemical and biophysical research communications.

[17]  A. Hewer,et al.  Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide , 1974, Nature.

[18]  P. Lazar,et al.  Validity of the Sebaceous Gland Test and the Hyperplasia Test for the Prediction of the Carcinogenicity of Cigarette Smoke Condensates and Their Fractions , 1974 .

[19]  P. Sims.  The metabolism of some aromatic hydrocarbons by mouse embryo cell cultures. , 1970, Biochemical pharmacology.

[20]  P. Sims.  The metabolism of 7- and 12-methylbenz[a]anthracene and their derivatives. , 1967, The Biochemical journal.

[21]  F. Bock,et al.  A survey of compounds for activity in the suppression of mouse sebaceous glands. , 1958, Cancer research.