Hsp90 isoforms: functions, expression and clinical importance

[1]  N. Wu,et al.  PKCϵ Is a Unique Regulator for hsp90β Gene in Heat Shock Response* , 2003, Journal of Biological Chemistry.

[2]  T. Cavalier-smith,et al.  Phylogenetic Analysis of Eukaryotes Using Heat-Shock Protein Hsp90 , 2003, Journal of Molecular Evolution.

[3]  L. Fritz,et al.  A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors , 2003, Nature.

[4]  P. Csermely,et al.  Hsp90 Inhibition Accelerates Cell Lysis , 2003, Journal of Biological Chemistry.

[5]  P. Csermely,et al.  Comparative analysis of the ATP-binding sites of Hsp90 by nucleotide affinity cleavage: a distinct nucleotide specificity of the C-terminal ATP-binding site. , 2003, European journal of biochemistry.

[6]  L. Neckers Development of small molecule Hsp90 inhibitors: utilizing both forward and reverse chemical genomics for drug identification. , 2003, Current medicinal chemistry.

[7]  P. Underhill,et al.  Molecular variation of human HSP90α and HSP90β genes in Caucasians , 2003 .

[8]  W. Pratt,et al.  Regulation of Signaling Protein Function and Trafficking by the hsp90/hsp70-Based Chaperone Machinery 1 , 2003, Experimental biology and medicine.

[9]  N. Rosen,et al.  Development of a purine-scaffold novel class of Hsp90 binders that inhibit the proliferation of cancer cells and induce the degradation of Her2 tyrosine kinase. , 2002, Bioorganic & medicinal chemistry.

[10]  D. Picard,et al.  Heat-shock protein 90, a chaperone for folding and regulation , 2002, Cellular and Molecular Life Sciences CMLS.

[11]  C. Kimmel,et al.  HSP90α, HSP90β, and p53 Expression following in Vitro Hyperthermia Exposure in Gestation Day 10 Rat Embryos , 2002 .

[12]  K. Kita,et al.  Involvement of human heat shock protein 90α in nicotine‐induced apoptosis , 2002 .

[13]  M. Rooze,et al.  Heat shock protein HSP86 expression during mouse embryo development, especially in the germ-line , 2002, Anatomy and Embryology.

[14]  P. Tsvetkov,et al.  Binding of ATP to Heat Shock Protein 90 , 2002, The Journal of Biological Chemistry.

[15]  C. Ramana,et al.  The Role of Hsp90N, a New Member of the Hsp90 Family, in Signal Transduction and Neoplastic Transformation* , 2002, The Journal of Biological Chemistry.

[16]  J. Buchner,et al.  Hsp90: Chaperoning signal transduction , 2001, Journal of cellular physiology.

[17]  A. Nakai,et al.  Cell cycle transition under stress conditions controlled by vertebrate heat shock factors , 2001, The EMBO journal.

[18]  K. Pepin,et al.  Molecular cloning of horse Hsp90 cDNA and its comparative analysis with other vertebrate Hsp90 sequences. , 2001, The Journal of veterinary medical science.

[19]  L. Neckers,et al.  The Heat Shock Protein 90 Antagonist Novobiocin Interacts with a Previously Unrecognized ATP-binding Domain in the Carboxyl Terminus of the Chaperone* , 2000, The Journal of Biological Chemistry.

[20]  Y. Moriyama,et al.  Overexpression and localization of heat shock proteins mRNA in pancreatic carcinoma. , 2000, Journal of Nippon Medical School = Nippon Ika Daigaku zasshi.

[21]  D. Donner,et al.  The hsp90-related Protein TRAP1 Is a Mitochondrial Protein with Distinct Functional Properties* , 2000, The Journal of Biological Chemistry.

[22]  J. Hata,et al.  Function of 90-kDa heat shock protein in cellular differentiation of human embryonal carcinoma cells , 2000, In Vitro Cellular & Developmental Biology - Animal.

[23]  X. Liu,et al.  Expression of heat shock protein 90 beta in human gastric cancer tissue and SGC7901/VCR of MDR-type gastric cancer cell line. , 1999, Chinese medical journal.

[24]  R. Maccioni,et al.  The β‐isoform of heat shock protein hsp‐90 is structurally related with human microtubule‐interacting protein Mip‐90 , 1999, FEBS letters.

[25]  G. Jung,et al.  Involvement of c-Jun NH(2)-terminal kinase pathway in differential regulation of heat shock proteins by anticancer drugs. , 1999, Biochemical and biophysical research communications.

[26]  Z. Lele,et al.  Disruption of zebrafish somite development by pharmacologic inhibition of Hsp90. , 1999, Developmental biology.

[27]  N. Wu,et al.  Regulation of human hsp90α gene expression , 1999, FEBS letters.

[28]  R. Quatrano Genomics , 1998, Plant Cell.

[29]  K. Irie,et al.  Radicicol Leads to Selective Depletion of Raf Kinase and Disrupts K-Ras-activated Aberrant Signaling Pathway* , 1998, The Journal of Biological Chemistry.

[30]  N. Wu,et al.  Essential role of the first intron in the transcription of hsp90β gene , 1997, FEBS letters.

[31]  W. Hiddemann,et al.  Increase of P-glycoprotein-mediated drug resistance by hsp 90b , 1996 .

[32]  G. Shyamala,et al.  Cloning and characterization of the promoter for murine 84-kDa heat-shock protein. , 1996, Gene.

[33]  R. Gupta,et al.  Phylogenetic analysis of the 90 kD heat shock family of protein sequences and an examination of the relationship among animals, plants, and fungi species. , 1995, Molecular biology and evolution.

[34]  H. Friess,et al.  Differential expression of heat shock proteins in pancreatic carcinoma. , 1994, Cancer research.

[35]  D. Maglott,et al.  Assignment of an intron-containing human heat-shock protein gene (hsp90 beta, HSPCB) to chromosome 6 near TCTE1 (6p21) and two intronless pseudogenes to chromosomes 4 and 15 by polymerase chain reaction amplification from a panel of hybrid cell lines. , 1993, Genomics.

[36]  D. Isenberg,et al.  Elevated levels of the 90 kD heat shock protein in patients with systemic lupus erythematosus are dependent upon enhanced transcription of the hsp90 beta gene. , 1993, Journal of autoimmunity.

[37]  E. Baulieu,et al.  Cell Cycle Regulation of the Chicken hsp90α Expression , 1993 .

[38]  E. Baulieu,et al.  Cloning of chicken hsp90β : the only vertebrate hsp90 insensitive to heat shock , 1993 .

[39]  H. Nawata,et al.  High constitutive expression of heat shock protein 90α in human acute leukemia cells , 1992 .

[40]  Y. Murakami,et al.  Mapping of the gene family for human heat-shock protein 90α to chromosomes 1, 4, 11, and 14 , 1992 .

[41]  R. Coombes,et al.  Clinical and biological significance of HSP89 alpha in human breast cancer , 1992, International journal of cancer.

[42]  D. Wolgemuth,et al.  Stage and lineage‐regulated expression of two HSP90 transcripts during mouse germ cell differentiation and embryogenesis , 1991, Molecular reproduction and development.

[43]  T. Ley,et al.  Nucleotide sequence and regulation of a human 90-kDa heat shock protein gene. , 1989, The Journal of biological chemistry.

[44]  L. Weber,et al.  Sequence and regulation of a gene encoding a human 89-kilodalton heat shock protein , 1989, Molecular and cellular biology.

[45]  S. Lindquist,et al.  RNA splicing is interrupted by heat shock and is rescued by heat shock protein synthesis , 1986, Cell.

[46]  G. Gauss,et al.  Kinetics of gametogenesis , 2004, Cell and Tissue Research.

[47]  L. Pearl,et al.  Structure, function, and mechanism of the Hsp90 molecular chaperone. , 2001, Advances in protein chemistry.

[48]  M. Saraste,et al.  FEBS Lett , 2000 .

[49]  P. Gruss,et al.  Mice lacking HSP90beta fail to develop a placental labyrinth. , 2000, Development.

[50]  P. Csermely,et al.  Associate Editor: D. Shugar The 90-kDa Molecular Chaperone Family: Structure, Function, and Clinical Applications. A Comprehensive Review , 1998 .

[51]  H. Fujita [Anticancer drugs]. , 1995, Nihon rinsho. Japanese journal of clinical medicine.

[52]  E. Baulieu,et al.  Growth factors acting via tyrosine kinase receptors induce HSP90 alpha gene expression. , 1991, Growth factors.

[53]  P. Csermely,et al.  A Nucleotide-dependent Molecular Switch Controls Atp Binding at the C-terminal Domain of Hsp90 N-terminal Nucleotide Binding Unmasks a C-terminal Binding Pocket* , 2022 .