Reconstruction of Coefficients in Scalar Second‐Order Elliptic Equations from Knowledge of Their Solutions

This paper concerns the reconstruction of possibly complex-valued coefficients in a second-order scalar elliptic equation posed on a bounded domain from knowledge of several solutions of that equation. We show that for a sufficiently large number of solutions and for an open set of corresponding boundary conditions, all coefficients can be uniquely and stably reconstructed up to a well characterized gauge transformation. We also show that in some specific situations, a minimum number of such available solutions equal to $I_n=\frac12n(n+3)$ is sufficient to uniquely and globally reconstruct the unknown coefficients. This theory finds applications in several coupled-physics medical imaging modalities including photo-acoustic tomography, transient elastography, and magnetic resonance elastography.

[1]  Kari Astala,et al.  Elliptic Partial Differential Equations and Quasiconformal Mappings in the Plane (Pms-48) , 2009 .

[2]  P. Lax,et al.  A stability theorem for solutions of abstract differential equations, and its application to the study of the local behavior of solutions of elliptic equations , 1956 .

[3]  Guillaume Bal,et al.  Hybrid inverse problems and internal functionals , 2011, 1110.4733.

[4]  Gen Nakamura,et al.  Inversion analysis for magnetic resonance elastography , 2008 .

[5]  Guillaume Bal,et al.  On multi-spectral quantitative photoacoustic tomography , 2011 .

[6]  Guillaume Bal,et al.  On multi-spectral quantitative photoacoustic tomography in diffusive regime , 2012 .

[7]  G. Richter An Inverse Problem for the Steady State Diffusion Equation , 1981 .

[8]  Habib Ammari,et al.  An Introduction to Mathematics of Emerging Biomedical Imaging , 2008 .

[9]  Lihong V. Wang,et al.  Dark-Field Confocal Photoacoustic Microscopy , 2009 .

[10]  L. Hörmander The Analysis of Linear Partial Differential Operators III , 2007 .

[11]  P. Bassanini,et al.  Elliptic Partial Differential Equations of Second Order , 1997 .

[12]  Claude Zuily,et al.  Uniqueness and Non-Uniqueness in the Cauchy Problem , 1983 .

[13]  O. Scherzer Handbook of mathematical methods in imaging , 2011 .

[14]  Guillaume Bal,et al.  Inverse diffusion theory of photoacoustics , 2009, 0910.2503.

[15]  Guillaume Bal,et al.  Reconstructions for some coupled-physics inverse problems , 2012, Appl. Math. Lett..

[16]  Lihong V. Wang Photoacoustic imaging and spectroscopy , 2009 .

[17]  A. Calderón,et al.  Uniqueness in the Cauchy Problem for Partial Differential Equations , 1958 .

[18]  Yu Jiang,et al.  Approximate Steady State Models for Magnetic Resonance Elastography , 2011, SIAM J. Appl. Math..

[19]  G. Bal,et al.  Inverse anisotropic diffusion from power density measurements in two dimensions , 2011, 1110.4606.

[20]  Gen Nakamura,et al.  Oscillating-decaying solutions, Runge approximation property for the anisotropic elasticity system and their applications to inverse problems , 2005 .

[21]  Guillaume Bal,et al.  Multi-source quantitative photoacoustic tomography in a diffusive regime , 2011 .

[22]  G. Uhlmann,et al.  Thermoacoustic tomography with variable sound speed , 2009, 0902.1973.

[23]  L. Nirenberg Uniqueness in Cauchy problems for differential equations with constant leading coefficients , 1957 .

[24]  Guillaume Bal,et al.  Multi-source quantitative PAT in diffusive regime , 2011 .

[25]  G. Eskin Lectures on Linear Partial Differential Equations , 2011 .

[26]  C. B. Morrey Multiple Integrals in the Calculus of Variations , 1966 .

[27]  L. Hörmander The analysis of linear partial differential operators , 1990 .

[28]  Gunther Uhlmann,et al.  Electrical impedance tomography and Calderón's problem , 2009 .

[29]  B. T. Cox,et al.  The challenges for quantitative photoacoustic imaging , 2009, BiOS.

[30]  G. Alessandrini An identification problem for an elliptic equation in two variables , 1986 .

[31]  Armando Manduca,et al.  Calculating tissue shear modulus and pressure by 2D log-elastographic methods , 2010, Inverse problems.

[32]  Habib Ammari,et al.  A method of biological tissues elasticity reconstruction using magnetic resonance elastography measurements , 2007 .

[33]  S. Arridge,et al.  Estimating chromophore distributions from multiwavelength photoacoustic images. , 2009, Journal of the Optical Society of America. A, Optics, image science, and vision.