The Safety Profile Studies of Kajal in Rabbits

3 Abstract: Kajal was analyzed chemically using standard method of AOAC and found Zinc (19.81%), Sulfur (2.98%), Total Ash (46.96%) and no Lead, Cadmium, Antimony, Mercury and Arsenic contents. The safety profile studies were carried out in rabbits (both male and female) by ocular route according to the standard method. The biochemical and elemental analysis of blood samples were carried out after 0, 45 and 90 days. All the animals exhibited normal physiological activities during the whole studies. Zinc levels remained constant throughout the experimental period in all test and control rabbits. No sulfur was detected in any group, despite its minor presence in the applied sample. No mortality of animals occurred and all animals remained healthy and active throughout the experimental period.

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