Implant system for treatment of the orbital blowout fractures in the maxillofacial region using polypropylene yarn and bioactive bone cement

Fractures in the craniofacial region are a serious problem in terms of treatment. The most reasonable solution is the use of individual implants dedicated to a specific patient. The aim of this study was to develop the implant system specifically for treatment of the orbital floor defects of blowout fractures of maxillofacial region, using polypropylene yarn and bone cement. Three types of bone cement were used to fix the polypropylene yarn: unmodified, antibiotic-loaded and modified with nanometals. The following research was carried out: selection of cement production parameters, assessment of the curing time, measurement of polymerization temperature, an analysis of microstructure and surface topography, evaluation of wettability, measurement of microhardness, and studies of bactericidal effectiveness. The research confirms the possibility of using bone cement and polypropylene yarn for an individual implant, dedicated to the fractures treatment in the maxillofacial region. Moreover, the bactericidal properties of the proposed modifications for bone cement have been verified, hence bioactive cements are recommended for use in the case of infectious complications.

[1]  N. Shaw.  Requirements , 2018, Computerization and Going Paperless in Canadian Primary Care.

[2]  G. Sundar,et al.  Permanent Versus Bioresorbable Implants in Orbital Floor Blowout Fractures. , 2018, Ophthalmic plastic and reconstructive surgery.

[3]  P. Greil,et al.  Modular ceramic scaffolds for individual implants. , 2018, Acta biomaterialia.

[4]  N. Moritz,et al.  Biomechanical testing of bioactive bone cements – a comparison of the impact of modifiers: antibiotics and nanometals , 2018, Polymer Testing.

[5]  Dominic Eggbeer,et al.  Reporting fidelity in the literature for computer aided design and additive manufacture of implants and guides , 2018, Additive Manufacturing.

[6]  T. Wada,et al.  Open porous dealloying-based biomaterials as a novel biomaterial platform. , 2018, Materials science & engineering. C, Materials for biological applications.

[7]  A. Banerjee,et al.  Role of porosity and matrix behavior on compressive fracture of Haversian bone using random spring network model. , 2018, Journal of the mechanical behavior of biomedical materials.

[8]  Dongxu Ke,et al.  Additive manufacturing of biomaterials. , 2018, Progress in materials science.

[9]  Lan Li,et al.  Design and fabrication of graduated porous Ti-based alloy implants for biomedical applications , 2017 .

[10]  L. Balan,et al.  Antibacterial properties and compressive strength of new one-step preparation silver nanoparticles in glass ionomer cements (NanoAg-GIC). , 2017, Journal of dentistry.

[11]  R. Narayan,et al.  Nanosilver-PMMA composite coating optimized to provide robust antibacterial efficacy while minimizing human bone marrow stromal cell toxicity. , 2017, Toxicology in vitro : an international journal published in association with BIBRA.

[12]  Wenbin Zhu,et al.  Synthesis of imidazolium-containing mono-methacrylates as polymerizable antibacterial agents for acrylic bone cements. , 2017, Journal of the mechanical behavior of biomedical materials.

[13]  D. Ulrich,et al.  A preclinical evaluation of polypropylene/polylacticacid hybrid meshes for fascial defect repair using a rat abdominal hernia model , 2017, Geburtshilfe und Frauenheilkunde.

[14]  C. Viozzi.  Maxillofacial and Mandibular Fractures in Sports. , 2017, Clinics in sports medicine.

[15]  Juliana Bonilla-Velez,et al.  Management of orbital fractures: challenges and solutions , 2015, Clinical ophthalmology.

[16]  J. D. del Real,et al.  Evaluation of Elution and Mechanical Properties of High-Dose Antibiotic-Loaded Bone Cement: Comparative "In Vitro" Study of the Influence of Vancomycin and Cefazolin. , 2015, The Journal of arthroplasty.

[17]  O. Ogle.  Implant surface material, design, and osseointegration. , 2015, Dental clinics of North America.

[18]  Juan F. Vivanco,et al.  Mechanical, material, and antimicrobial properties of acrylic bone cement impregnated with silver nanoparticles. , 2015, Materials science & engineering. C, Materials for biological applications.

[19]  G. Lucchetta,et al.  Antibiotic-free composite bone cements with antibacterial and bioactive properties. A preliminary study. , 2014, Materials science & engineering. C, Materials for biological applications.

[20]  Paul J. Schmitt,et al.  Surgical perspectives in craniofacial trauma. , 2014, Neuroimaging clinics of North America.

[21]  Marcin Kozakiewicz,et al.  Computer-aided orbital wall defects treatment by individual design ultrahigh molecular weight polyethylene implants. , 2014, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.

[22]  M. Blauth,et al.  Principles of osteoporotic fracture treatment. , 2013, Best practice & research. Clinical rheumatology.

[23]  S. N. Khan,et al.  Osseointegration and more–A review of literature , 2012 .

[24]  Forrest S. Roth,et al.  Pearls of Orbital Trauma Management , 2010, Seminars in plastic surgery.

[25]  W. Dhert,et al.  No efficacy of silver bone cement in the prevention of methicillin‐sensitive Staphylococcal infections in a rabbit contaminated implant bed model , 2009, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[26]  Marcin Wekwejt,et al.  Badania bioaktywności modyfikowanego cementu kostnego – przegląd literaturowy , 2017 .

[27]  K. Saleh,et al.  Acrylic bone cements for joint replacement , 2017 .

[28]  Marek Szkodo,et al.  Requirements, modifications and methods of mechanical testing of bone cement – literature review , 2017 .

[29]  Zhang Wentao,et al.  Approach to osteomyelitis treatment with antibiotic loaded PMMA. , 2017, Microbial pathogenesis.

[30]  B. Świeczko-Żurek.  Antimicrobal and ostheointegration activity of bone cement contains nanometals , 2016 .

[31]  R. Ciuluvică,et al.  Biomaterials for orbital fractures repair , 2015, Journal of medicine and life.

[32]  D. Seligson.  Orthopedic infections. , 1994, Orthopedics.