All fiber 1064-nm time-lens source for coherent anti-Stokes Raman scattering and stimulated Raman scattering microscopy

We use the time-lens concept to demonstrate a new scheme for synchronization of two pulsed light sources for biological imaging. An all fiber, 1064 nm time-lens source is synchronized to a picosecond solid-state Ti: Sapphire mode-locked laser by using the mode-locked laser pulses as the clock. We demonstrate the application of this synchronized source for CARS and SRS imaging by imaging mouse tissues. Synchronized two wavelength pulsed source is a major technical difficulty for CARS and SRS imaging. The time-lens source demonstrated here may provide an all-fiber, user friendly alternative for future SRS imaging.

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