Enantioselective conjugate addition of Grignard reagents to enones catalyzed by chiral cuprate complexes

The enantioselective conjugate addition of Grignard reagents to enones catalyzed by copper (I) complexes with bidentate chiral auxiliary ligands, N,N'-dialkyl-substituted aminotropone iminates has been studied. The enantioselectivity of the reaction was significantly increased by addition of HMPA and silyl reagents