Gas exchange modelling: no more gills, please.

[1]  P J Hunter,et al.  Multibreath washout analysis: modelling the influence of conducting airway asymmetry. , 2001, Respiration physiology.

[2]  A Zwart,et al.  Ventilation-perfusion ratio obtained by a noninvasive frequency response technique. , 1976, Journal of applied physiology.

[3]  C E Hahn,et al.  Assessment of cardiorespiratory function using oscillating inert gas forcing signals. , 1994, Journal of applied physiology.

[4]  T. Yokoyama,et al.  Effects of ventilation-perfusion inequality on elimination of inert gases. , 1967, Respiration physiology.

[5]  M J Purves,et al.  Fluctuations of arterial oxygen tension which have the same period as respiration. , 1966, Respiration physiology.

[6]  Martin J. Tobin,et al.  Principles and Practice of Intensive Care Monitoring. , 1997 .

[7]  P. Wagner.  Pulmonary gas exchange , 2007, American journal of respiratory and critical care medicine.

[8]  C. Otto,et al.  Effects of respiratory rate, plateau pressure, and positive end-expiratory pressure on PaO2 oscillations after saline lavage. , 2002, American journal of respiratory and critical care medicine.

[9]  J. West.  Regional differences in the lung. , 1968, Chest.

[10]  T. Raffin,et al.  Indices of hypoxemia in patients with acute respiratory distress syndrome: reliability, validity, and clinical usefulness. , 1997, Critical care medicine.

[11]  P. Peyton,et al.  Ventilation-perfusion inhomogeneity increases gas uptake in anesthesia: computer modeling of gas exchange. , 2001, Journal of applied physiology.

[12]  J B West,et al.  Pulmonary gas exchange. , 1998, International review of physiology.

[13]  P. Peyton,et al.  Ventilation-perfusion inhomogeneity increases gas uptake: theoretical modeling of gas exchange. , 2001, Journal of applied physiology.

[14]  J. Vincent,et al.  Yearbook of Intensive Care and Emergency Medicine , 1995, Yearbook of Intensive Care and Emergency Medicine.

[15]  A. Farmery,et al.  A tidal ventilation model for oxygenation in respiratory failure , 2003, Respiratory Physiology & Neurobiology.

[16]  B. Lachmann,et al.  Open up the lung and keep the lung open , 1992, Intensive Care Medicine.

[17]  J. West.  Bioengineering aspects of the lung , 1977 .

[18]  J. Piiper,et al.  4 – Intrapulmonary Gas Mixing and Stratification , 1980 .

[19]  H. Folgering,et al.  Respiratory oscillations of the arterial $$P_{{\text{O}}_{\text{2}} }$$ and their effects on the ventilatory controlling system in the cat , 1978, Pflügers Archiv.

[20]  Michael P. Hlastala,et al.  Physiology of respiration , 1996 .

[21]  P. J. Hunter,et al.  Generation of an Anatomically Based Three-Dimensional Model of the Conducting Airways , 2000, Annals of Biomedical Engineering.

[22]  C. Hahn,et al.  A tidal breathing model of the inert gas sinewave technique for inhomogeneous lungs. , 2000, Respiration physiology.

[23]  J. D. Young.  Hypoxemia and Mortality in the ICU , 2000 .

[24]  J. W. Boretos,et al.  Physiological and clinical aspects of oxygenator design : (Proceedings of the seminar, copenhagen, June 15-20, 1975). edited by S.G. Dawids and H.C. Engell, Elsevier Scientific Publishing Co., Amsterdam, 1976, xviii + 330 pp., ISBN 0-444-41453-3, Dfl. 96.00/US $39.25. , 1978 .

[25]  Engel La,et al.  Gas Mixing and Distribution in the Lung , 1985 .

[26]  John F. Nunn,et al.  Applied Respiratory Physiology , 1977 .

[27]  S. Lewis,et al.  Continuous distributions of specific ventilation recovered from inert gas washout. , 1978, Journal of applied physiology: respiratory, environmental and exercise physiology.

[28]  R. Klocke,et al.  Variability of indices of hypoxemia in adult respiratory distress syndrome. , 1997, Critical care medicine.

[29]  C. Hahn,et al.  A reconciliation of continuous and tidal ventilation gas exchange models. , 1997, Respiration physiology.

[30]  H. Kaufman,et al.  Continuous Pulmonary Capillary Blood Flow Estimation from Measurements of Respiratory Anesthetic Gas Concentration , 1985, IEEE Transactions on Biomedical Engineering.

[31]  R. Carnap,et al.  INTERNATIONAL ENCYCLOPEDIA OF UNIFIED SCIENCE. , 1939, Science.

[32]  Donald M. Wiberg,et al.  The extended Kalman filter as a pulmonary blood flow estimator , 1981, Autom..

[33]  L. Farhi.  Elimination of inert gas by the lung. , 1967, Respiration physiology.

[34]  P. Peyton,et al.  Effect of ventilation-perfusion inhomogeneity and N(2)O on oxygenation: physiological modeling of gas exchange. , 2001, Journal of applied physiology.

[35]  J P Viale,et al.  Within-breath arterial PO2 oscillations in an experimental model of acute respiratory distress syndrome. , 2000, British journal of anaesthesia.

[36]  C. Hahn,et al.  Gas exchange in a three-compartment lung model analyzed by forcing sinusoids of N2O. , 1993, Journal of applied physiology.

[37]  B. Shapiro,et al.  Unreliability of oxygen tension-based indices in reflecting intrapulmonary shunting in critically ill patients. , 1988, Critical care medicine.

[38]  P J Hunter,et al.  Characterising respiratory airway gas mixing using a lumped parameter model of the pulmonary acinus. , 2001, Respiration physiology.

[39]  N. A. Bergman,et al.  CYCLIC VARIATIONS IN BLOOD OXYGENATION WITH THE RESPIRATORY CYCLE , 1961, Anesthesiology.

[40]  C. Hahn,et al.  The effects of ventilation pattern on carbon dioxide transfer in three computer models of the airways , 2002, Respiratory Physiology & Neurobiology.

[41]  H. Stam,et al.  Design and validation of an indicator gas injector for multiple gas washout tests in mechanically ventilated patients , 1990, Critical care medicine.

[42]  P. Larsen,et al.  Cardioventilatory coupling in atrial fibrillation. , 1999, British journal of anaesthesia.

[43]  D J Gavaghan,et al.  A tidal breathing model of the forced inspired inert gas sinewave technique. , 1996, Respiration physiology.

[44]  C. Hahn,et al.  Pulmonary blood flow measured by inspiratory inert gas concentration forcing oscillations. , 1998, Respiration physiology.

[45]  H. Robertson,et al.  Complexity in structure and function of the lung , 1998 .

[46]  H. Zetterström.  Assessment of the efficiency of pulmonary oxygenation. The choice of oxygenation index , 1988, Acta anaesthesiologica Scandinavica.

[47]  M. Paiva.  Theoretical studies of gas mixing in the lung , 1985 .

[48]  A. Cournand,et al.  STUDIES ON THE INTRAPULMONARY MIXTURE OF GASES. III. AN OPEN CIRCUIT METHOD FOR MEASURING RESIDUAL AIR. , 1940, The Journal of clinical investigation.

[49]  T. Feeley,et al.  Changes in Venous Admixture with Alterations of Inspired Oxygen Concentration , 1980, Anesthesiology.

[50]  T. Kuhn,et al.  The Structure of Scientific Revolutions. , 1964 .

[51]  Ewald R. Weibel,et al.  The pathway for oxygen : structure and function in the mammalian respiratory system , 1984 .

[52]  R. Lewontin,et al.  Organism and environment , 1997 .

[53]  Peter D. Wagner,et al.  8 – Numerical Analysis of Gas Exchange , 1980 .

[54]  C. Hahn,et al.  A tidal breathing model for the multiple inert gas elimination technique. , 1999, Journal of applied physiology.

[55]  T G Buchman,et al.  Uncoupling of biological oscillators: a complementary hypothesis concerning the pathogenesis of multiple organ dysfunction syndrome. , 1996, Critical care medicine.

[56]  E. Weibel.  Morphometry of the Human Lung , 1965, Springer Berlin Heidelberg.

[57]  Arthur S Slutsky,et al.  Estimation Of Ventilation-perfusion Ratio Distribution In The Lung By Respiratory Gas Analysis , 1991, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society Volume 13: 1991.

[58]  J. Brunner,et al.  A simple method to estimate functional residual capacity in mechanically ventilated patients , 2005, Intensive Care Medicine.