Search for new tools to combat Gram-negative resistant bacteria among amine derivatives of 5-arylidenehydantoin.

[1]  J. Karolak-Wojciechowska,et al.  Synthesis and SAR-study for novel arylpiperazine derivatives of 5-arylidenehydantoin with α₁-adrenoceptor antagonistic properties. , 2012, Bioorganic & medicinal chemistry.

[2]  J. Handzlik,et al.  Antiarrhythmic properties of phenylpiperazine derivatives of phenytoin with α₁-adrenoceptor affinities. , 2012, Bioorganic & medicinal chemistry.

[3]  J. Handzlik,et al.  Amine-alkyl derivatives of hydantoin: new tool to combat resistant bacteria. , 2011, European journal of medicinal chemistry.

[4]  J. Handzlik,et al.  Strategies for bypassing the membrane barrier in multidrug resistant Gram‐negative bacteria , 2011, FEBS letters.

[5]  J. Pagés,et al.  An original deal for new molecule: reversal of efflux pump activity, a rational strategy to combat gram-negative resistant bacteria. , 2011, Current medicinal chemistry.

[6]  J. Handzlik,et al.  Pharmacophore models based studies on the affinity and selectivity toward 5-HT1A with reference to α1-adrenergic receptors among arylpiperazine derivatives of phenytoin. , 2011, Bioorganic & medicinal chemistry.

[7]  J. Handzlik,et al.  Search for influence of spatial properties on affinity at α1-adrenoceptor subtypes for phenylpiperazine derivatives of phenytoin. , 2010, Bioorganic & medicinal chemistry letters.

[8]  K. Kieć‐Kononowicz,et al.  Synthesis of 5-arylidene-2-amino-4-azolones and evaluation of their anticancer activity. , 2010, Bioorganic & medicinal chemistry.

[9]  K. Kieć‐Kononowicz,et al.  Crystallographic studies of ( Z ) and ( E ) isomers of 2-amino-5-(2-chlorobenzylidene)-1-methyl-1H-imidazol-4(5H)-one , 2010 .

[10]  K. Kieć‐Kononowicz,et al.  Crystallographic and spectroscopic studies of 5-arylidene-2-amino-imidazol-4-ones , 2009 .

[11]  H. Nikaido,et al.  Mechanisms of RND multidrug efflux pumps. , 2009, Biochimica et biophysica acta.

[12]  J. Pagés,et al.  Mechanisms of drug efflux and strategies to combat them: challenging the efflux pump of Gram-negative bacteria. , 2009, Biochimica et biophysica acta.

[13]  J. Handzlik,et al.  Synthesis, alpha 1-adrenoceptor antagonist activity, and SAR study of novel arylpiperazine derivatives of phenytoin. , 2008, Bioorganic & medicinal chemistry.

[14]  J. Frère,et al.  Treatment of health-care-associated infections caused by Gram-negative bacteria: a consensus statement. , 2008, The Lancet. Infectious diseases.

[15]  M. Totrov,et al.  Waltzing transporters and 'the dance macabre' between humans and bacteria , 2007, Nature Reviews Drug Discovery.

[16]  E. Mini,et al.  Pharmacological strategies for overcoming multidrug resistance. , 2006, Current drug targets.

[17]  J. Pagés,et al.  Quinoline derivatives as promising inhibitors of antibiotic efflux pump in multidrug resistant Enterobacter aerogenes isolates. , 2006, Current drug targets.

[18]  I. Paulsen,et al.  Microbial drug efflux proteins of the major facilitator superfamily. , 2006, Current drug targets.

[19]  K. Kieć‐Kononowicz,et al.  Synthesis, structure-activity relationship of some new anti-arrhythmic 5-arylidene imidazolidine-2,4-dione derivatives. , 2005, European journal of medicinal chemistry.

[20]  K. Kieć‐Kononowicz,et al.  Synthesis, structure and antiarrhythmic properties evaluation of new basic derivatives of 5,5-diphenylhydantoin. , 2003, European journal of medicinal chemistry.

[21]  S. Dei,et al.  The medicinal chemistry of multidrug resistance (MDR) reversing drugs. , 2002, Farmaco.

[22]  K. Kieć‐Kononowicz,et al.  Antimycobacterial activity of 5-arylidene aromatic derivatives of hydantoin. , 2002, Farmaco.

[23]  K. Kieć‐Kononowicz,et al.  Antimicrobial activity of 5-arylidene aromatic derivatives of hydantoin. Part 2. , 2002, Farmaco.

[24]  J. Marton,et al.  Preparation and fungicidal activity of 5-substituted hydantoins and their 2-thio analogs , 1993 .

[25]  K. Ang,et al.  NMR spectroscopic study of configurations and conformations of 5-pyridylmethylenehydantoins , 1990 .

[26]  K. Ang,et al.  (Z)- and (E)-5-Arylmethylenehydantoins: spectroscopic properties and configuration assignment , 1986 .