Nanoparticle-based immunotherapeutics: from the properties of nanocores to the differential effects of administration routes.

[1]  H. Goldschmidt,et al.  The pre-existing T cell landscape determines the response to bispecific T cell engagers in multiple myeloma patients. , 2023, Cancer cell.

[2]  B. Pelaz,et al.  Nanosized metal–organic frameworks as unique platforms for bioapplications , 2023, Chemical communications.

[3]  B. Pelaz,et al.  Biomimetic cell-derived nanocarriers in cancer research , 2022, Journal of nanobiotechnology.

[4]  Chaotao Hu,et al.  Application of nanosonosensitizer materials in cancer sono-dynamic therapy , 2022, RSC advances.

[5]  C. Agrati,et al.  Coordinated innate and T-cell immune responses in mild COVID-19 patients from household contacts of COVID-19 cases during the first pandemic wave , 2022, Frontiers in Immunology.

[6]  E. Topol,et al.  Operation Nasal Vaccine—Lightning speed to counter COVID-19 , 2022, Science Immunology.

[7]  Neil C. Dalvie,et al.  Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity , 2022, Science Translational Medicine.

[8]  Aaron J. Johnson,et al.  Respiratory mucosal immunity against SARS-CoV-2 following mRNA vaccination , 2022, Science Immunology.

[9]  Chenjie Xu,et al.  Precision cancer sono-immunotherapy using deep-tissue activatable semiconducting polymer immunomodulatory nanoparticles , 2022, Nature Communications.

[10]  Yannan Yang,et al.  Nanostructured Organosilica Nitric Oxide Donors Intrinsically Regulate Macrophage Polarization with Antitumor Effect. , 2022, ACS nano.

[11]  L. Calzolai,et al.  Characterization of nanoparticles-based vaccines for COVID-19 , 2022, Nature Nanotechnology.

[12]  Yu Chen,et al.  Nanoparticle-enhanced radiotherapy synergizes with PD-L1 blockade to limit post-surgical cancer recurrence and metastasis , 2022, Nature Communications.

[13]  Y. Oh,et al.  In vivo fate and intracellular trafficking of vaccine delivery systems , 2022, Advanced Drug Delivery Reviews.

[14]  H. Yang,et al.  Artificial Assembled Macrophage Co-Deliver Black Phosphorus Quantum Dot and CDK4/6 Inhibitor for Colorectal Cancer Triple-Therapy. , 2022, ACS applied materials & interfaces.

[15]  K. Willard-Gallo,et al.  T follicular helper and B cell crosstalk in tertiary lymphoid structures and cancer immunotherapy , 2022, Nature Communications.

[16]  Raghavendra Kikkeri,et al.  The Shape of Nanostructures Encodes Immunomodulation of Carbohydrate Antigen and Vaccine Development. , 2022, ACS chemical biology.

[17]  L. Bian,et al.  The Effect of the Nanoparticle Shape on T Cell Activation. , 2022, Small.

[18]  K. Roe.  NK‐cell exhaustion, B‐cell exhaustion and T‐cell exhaustion—the differences and similarities , 2022, Immunology.

[19]  Hongming Song,et al.  IR792-MCN@ZIF-8-PD-L1 siRNA drug delivery system enhances photothermal immunotherapy for triple-negative breast cancer under near-infrared laser irradiation , 2022, Journal of Nanobiotechnology.

[20]  Pei Cao,et al.  Tailoring functional nanoparticles for oral vaccine delivery: Recent advances and future perspectives , 2022, Composites Part B: Engineering.

[21]  L. Zitvogel,et al.  Immunogenic cell stress and death , 2022, Nature Immunology.

[22]  Zhigang Wang,et al.  Near-Infrared II Nanoadjuvant-Mediated Chemodynamic, Photodynamic, and Photothermal Therapy Combines Immunogenic Cell Death with PD-L1 Blockade to Enhance Antitumor Immunity. , 2022, Small.

[23]  M. Netea,et al.  Regulating trained immunity with nanomedicine , 2022, Nature Reviews Materials.

[24]  Christian J. Konopka,et al.  Dextran-Mimetic Quantum Dots for Multimodal Macrophage Imaging In Vivo, Ex Vivo, and In Situ. , 2022, ACS nano.

[25]  Yining Zhu,et al.  Aluminum nanoparticles deliver a dual-epitope peptide for enhanced anti-tumor immunotherapy. , 2022, Journal of controlled release : official journal of the Controlled Release Society.

[26]  N. Dantas,et al.  CdSe magic-sized quantum dots attenuate reactive oxygen species generated by neutrophils and macrophages with implications in experimental arthritis. , 2022, Nanomedicine : nanotechnology, biology, and medicine.

[27]  Z. Teng,et al.  Flower-like mesoporous silica nanoparticles as an antigen delivery platform to promote systemic immune response. , 2022, Nanomedicine : nanotechnology, biology, and medicine.

[28]  M. Diamond,et al.  Innate immunity: the first line of defense against SARS-CoV-2 , 2022, Nature Immunology.

[29]  Q. Lu,et al.  A nano-innate immune system activator for cancer therapy in a 4T1 tumor-bearing mouse model , 2022, Journal of Nanobiotechnology.

[30]  J. Gray,et al.  Targeted Nanoparticle for Co-delivery of HER2 siRNA and a Taxane to Mirror the Standard Treatment of HER2+ Breast Cancer: Efficacy in Breast Tumor and Brain Metastasis. , 2022, Small.

[31]  T. Hyeon,et al.  Enhanced Chemodynamic Therapy by Cu-Fe Peroxide Nanoparticles: Tumor Microenvironment-Mediated Synergistic Fenton Reaction. , 2022, ACS nano.

[32]  Xiqun Jiang,et al.  Enhancing Penetration Ability of Semiconducting Polymer Nanoparticles for Sonodynamic Therapy of Large Solid Tumor , 2022, Advanced science.

[33]  Meiwan Chen,et al.  Microfluidic Synthesis of Manganese-Alginate Nanogels with Self-Supplying H2O2 Capability for Synergistic Chemo/Chemodynamic Therapy and Boosting Anticancer Immunity , 2022, Chemical Engineering Journal.

[34]  N. Kotov,et al.  Enantiomer-dependent immunological response to chiral nanoparticles , 2022, Nature.

[35]  Wei Zhang,et al.  Biomimetic manganese-eumelanin nanocomposites for combined hyperthermia-immunotherapy against prostate cancer , 2021, Journal of Nanobiotechnology.

[36]  K. Dawson,et al.  A Nanoscale Shape-Discovery Framework Supporting Systematic Investigations of Shape-Dependent Biological Effects and Immunomodulation , 2021, ACS nano.

[37]  Weiqi Wang,et al.  Insights on functionalized carbon nanotubes for cancer theranostics , 2021, Journal of Nanobiotechnology.

[38]  N. Michael,et al.  SARS-CoV-2 ferritin nanoparticle vaccine induces robust innate immune activity driving polyfunctional spike-specific T cell responses , 2021, npj Vaccines.

[39]  C. Roberts,et al.  The role of nanoparticle format and route of administration on self-amplifying mRNA vaccine potency , 2021, Journal of Controlled Release.

[40]  Ronnie H. Fang,et al.  Acute myeloid leukemia cell membrane-coated nanoparticles for cancer vaccination immunotherapy , 2021, Leukemia.

[41]  M. Buggert,et al.  Human mucosal tissue-resident memory T cells in health and disease , 2021, Mucosal Immunology.

[42]  Wangxiao He,et al.  A Tumor-Targeting Metal-Organic Nanoparticle Constructed by Dynamic Combinatorial Chemistry toward Accurately Redressing Carcinogenic Wnt Cascade. , 2021, Small.

[43]  Yuxin Guo,et al.  Chemodynamic Therapy via Fenton and Fenton-Like Nanomaterials: Strategies and Recent Advances. , 2021, Small.

[44]  H. Ghandehari,et al.  Mechanisms of Immune Response to Inorganic Nanoparticles and Their Degradation Products. , 2021, Advanced drug delivery reviews.

[45]  Conglian Yang,et al.  Cell-Derived Biogenetic Gold Nanoparticles for Sensitizing Radiotherapy and Boosting Immune Response against Cancer. , 2021, Small.

[46]  T. Pellegrino,et al.  Magnetic nanoparticles and clusters for magnetic hyperthermia: optimizing their heat performance and developing combinatorial therapies to tackle cancer. , 2021, Chemical Society reviews.

[47]  Yan Yang,et al.  Nanofactory for metabolic and chemodynamic therapy: pro-tumor lactate trapping and anti-tumor ROS transition , 2021, Journal of Nanobiotechnology.

[48]  Min Wang,et al.  The Dynamic Interactions between Nanoparticles and Macrophages Impact Their Fate in Brain Tumors. , 2021, Small.

[49]  A. Samia,et al.  Hyperthermia-mediated changes in the tumor immune microenvironment using iron oxide nanoparticles , 2021, Nanoscale advances.

[50]  R. Rotomskis,et al.  Uptake of Upconverting Nanoparticles by Breast Cancer Cells: Surface Coating versus the Protein Corona , 2021, ACS applied materials & interfaces.

[51]  D. Zhao,et al.  Imparting multi-functionality to covalent organic framework nanoparticles by the dual-ligand assistant encapsulation strategy , 2021, Nature Communications.

[52]  R. Grose,et al.  Tumour microenvironment 3D-modelling: simplicity to complexity and back again. , 2021, Trends in cancer.

[53]  T. Randall,et al.  Scent of a vaccine , 2021, Science.

[54]  R. Oueslati,et al.  Silver nanoparticles’ impact on the gene expression of the cytosolic adaptor MyD-88 and the interferon regulatory factor IRF in the gills and digestive gland of mytilus galloprovincialis , 2021, Drug and chemical toxicology.

[55]  Cong Song,et al.  Overcoming T Cell Exhaustion via Immune Checkpoint Modulation with a Dendrimer‐Based Hybrid Nanocomplex , 2021, Advanced healthcare materials.

[56]  F. Voncken,et al.  Contemporary radiotherapy: present and future , 2021, The Lancet.

[57]  Qun Wang,et al.  Effects of polyethylene glycol on the surface of nanoparticles for targeted drug delivery. , 2021, Nanoscale.

[58]  J. Conde,et al.  Nanomedicine-based strategies to target and modulate the tumor microenvironment. , 2021, Trends in cancer.

[59]  Xiangliang Yang,et al.  Biomimetic sonodynamic therapy-nanovaccine integration platform potentiates Anti-PD-1 therapy in hypoxic tumors , 2021, Nano Today.

[60]  P. Ritprajak,et al.  Facile synthesis of magnetic silica-mannan nanocomposites for enhancement in internalization and immune response of dendritic cells , 2021 .

[61]  T. Pellegrino,et al.  Magnetic Nanostructures as Emerging Therapeutic Tools to Boost Anti-Tumour Immunity , 2021, Cancers.

[62]  S. De Gendt,et al.  Multicomponent Covalent Chemical Patterning of Graphene. , 2021, ACS nano.

[63]  D. Ling,et al.  Low-dose X-ray enhanced tumor accumulation of theranostic nanoparticles for high-performance bimodal imaging-guided photothermal therapy , 2021, Journal of Nanobiotechnology.

[64]  Shaobing Zhou,et al.  Polarization of Tumor-Associated Macrophages by Nanoparticle-Loaded Escherichia coli Combined with Immunogenic Cell Death for Cancer Immunotherapy. , 2021, Nano letters.

[65]  V. Puntes,et al.  Gold nanoparticles (AuNPs) impair LPS-driven immune responses by promoting a tolerogenic-like dendritic cell phenotype with altered endosomal structures , 2021, Nanoscale.

[66]  Teri W. Odom,et al.  Nanoparticle Shape Determines Dynamics of Targeting Nanoconstructs on Cell Membranes. , 2021, Journal of the American Chemical Society.

[67]  Q. Pankhurst,et al.  Potential of Magnetic Hyperthermia to Stimulate Localized Immune Activation. , 2021, Small.

[68]  D. Baker,et al.  Quadrivalent influenza nanoparticle vaccines induce broad protection , 2021, Nature.

[69]  R. Parton,et al.  Key principles and methods for studying the endocytosis of biological and nanoparticle therapeutics , 2021, Nature Nanotechnology.

[70]  Y. Daali,et al.  Mesoporous Silica Nanoparticles as pH-Responsive Carrier for the Immune-Activating Drug Resiquimod Enhance the Local Immune Response in Mice. , 2021, ACS nano.

[71]  Hong Yang,et al.  Administration route governs the therapeutic efficacy, biodistribution and macrophage targeting of anti-inflammatory nanoparticles in the lung , 2021, Journal of Nanobiotechnology.

[72]  Fernando Torres Andón,et al.  Nano‐Oncologicals: A Tortoise Trail Reaching New Avenues , 2021, Advanced Functional Materials.

[73]  M. Shawkey,et al.  Unraveling the Structure and Function of Melanin through Synthesis. , 2021, Journal of the American Chemical Society.

[74]  Z. Teng,et al.  Bi-functional gold Nanocages enhance specific immunological responses of foot-and-mouth disease virus-like particles vaccine as a carrier and adjuvant. , 2021, Nanomedicine : nanotechnology, biology, and medicine.

[75]  J. Boudon,et al.  In vivo protein corona on nanoparticles: does the control of all material parameters orient the biological behavior? , 2021, Nanoscale advances.

[76]  Jop de Vrieze.  Pfizer's vaccine raises allergy concerns. , 2021, Science.

[77]  Xiaolong Liu,et al.  Localized NIR-II photo-immunotherapy through the combination of photothermal ablation and in situ generated interleukin-12 cytokine for efficiently eliminating primary and abscopal tumors. , 2020, Nanoscale.

[78]  S. Sacanna,et al.  Modulation of Immune Responses by Particle Size and Shape , 2021, Frontiers in Immunology.

[79]  Y. Yao,et al.  Effective and Safe Stimulation of Humoral and Cell-Mediated Immunity by Intradermal Immunization with a Cyclic Dinucleotide/Nanoparticle Combination Adjuvant , 2020, The Journal of Immunology.

[80]  Cheng-Hsun Wu,et al.  STING Activator c-di-GMP-Loaded Mesoporous Silica Nanoparticles Enhance Immunotherapy Against Breast Cancer. , 2020, ACS applied materials & interfaces.

[81]  Jun Lin,et al.  Intelligent MoS2-CuO heterostructures with multiplexed imaging and remarkably enhanced antitumor efficacy via synergetic photothermal therapy/ chemodynamic therapy/ immunotherapy. , 2020, Biomaterials.

[82]  Qiqing Zhang,et al.  An Intelligent Biomimetic Nanoplatform for Holistic Treatment of Metastatic Triple-Negative Breast Cancer via Photothermal Ablation and Immune Remodeling. , 2020, ACS nano.

[83]  K. Leong,et al.  Nanoparticle-Enabled Dual Modulation of Phagocytic Signals to Improve Macrophage-Mediated Cancer Immunotherapy. , 2020, Small.

[84]  Paul C. Wang,et al.  Proton-driven transformable nanovaccine for cancer immunotherapy , 2020, Nature Nanotechnology.

[85]  Jun Xu,et al.  Sonodynamic therapy with immune modulatable two-dimensional coordination nanosheets for enhanced anti-tumor immunotherapy , 2020, Nano Research.

[86]  F. Ginhoux,et al.  Intravenous Nanoparticle Vaccination Generates Stem-Like TCF1+ Neoantigen-Specific CD8+ T Cells , 2020, Nature immunology.

[87]  Daniel W. Kulp,et al.  A DNA-Launched Nanoparticle Vaccine Elicits CD8+ T-cell Immunity to Promote In Vivo Tumor Control , 2020, Cancer Immunology Research.

[88]  S. Singamaneni,et al.  Polydopamine-Mesoporous Silica Core-Shell Nanoparticles for Combined Photothermal-Immunotherapy. , 2020, ACS applied materials & interfaces.

[89]  J. Collier,et al.  Advances in nanomaterial vaccine strategies to address infectious diseases impacting global health , 2020, Nature Nanotechnology.

[90]  Chaoqun You,et al.  A pH-activated autocatalytic nanoreactor for self-boosting Fenton-like chemodynamic therapy. , 2020, Nanoscale.

[91]  S. Masters,et al.  Constitutive immune mechanisms: mediators of host defence and immune regulation , 2020, Nature Reviews Immunology.

[92]  A. Ito,et al.  A nanoscale metal organic frameworks-based vaccine synergises with PD-1 blockade to potentiate anti-tumour immunity , 2020, Nature Communications.

[93]  A. Singh,et al.  Role of gold nanoparticles in advanced biomedical applications , 2020, Nanoscale advances.

[94]  S. Mazzucchelli,et al.  Indocyanine Green Nanoparticles: Are They Compelling for Cancer Treatment? , 2020, Frontiers in Chemistry.

[95]  C. Brander,et al.  TOX is expressed by exhausted and polyfunctional human effector memory CD8+ T cells , 2020, Science Immunology.

[96]  J. L. Jiménez Blanco,et al.  Nanoparticle-Delivered HIV Peptides to Dendritic Cells a Promising Approach to Generate a Therapeutic Vaccine , 2020, Pharmaceutics.

[97]  C. Pao,et al.  Modulating Performance and Stability of Inorganic Lead-Free Perovskite Solar Cells via Lewis-pair mediation. , 2020, ACS applied materials & interfaces.

[98]  K. Dawson,et al.  Classification and biological identity of complex nano shapes , 2020, Communications Materials.

[99]  Jun Xu,et al.  Photosensitizer-Modified MnO2 Nanoparticles to Enhance Photodynamic Treatment of Abscesses and Boost Immune Protection for Treated Mice. , 2020, Small.

[100]  V. Canzonieri,et al.  Self-Therapeutic Nanomaterials for Cancer Therapy: A Review , 2020 .

[101]  B. Espiña,et al.  Magnetic Hyperthermia for Cancer Treatment: Main Parameters Affecting the Outcome of In Vitro and In Vivo Studies , 2020, Molecules.

[102]  Xiaofang Zhong,et al.  The pore size of mesoporous silica nanoparticles regulates their antigen delivery efficiency , 2020, Science Advances.

[103]  E. Richardson,et al.  Revisiting the role of CD4+ T cells in cancer immunotherapy—new insights into old paradigms , 2020, Cancer Gene Therapy.

[104]  M. Lenardo,et al.  A guide to cancer immunotherapy: from T cell basic science to clinical practice , 2020, Nature Reviews Immunology.

[105]  Peifeng Li,et al.  Reactive Oxygen Species-Related Nanoparticle Toxicity in the Biomedical Field , 2020, Nanoscale Research Letters.

[106]  A. Loskog,et al.  The Tumor Microenvironment: A Milieu Hindering and Obstructing Antitumor Immune Responses , 2020, Frontiers in Immunology.

[107]  Qijie Zhao,et al.  Engineering nanoparticles to reprogram radiotherapy and immunotherapy: recent advances and future challenges , 2020, Journal of Nanobiotechnology.

[108]  Xiangyang Shi,et al.  Adoptive cellular immunotherapy of tumors via effective CpG delivery to dendritic cells using dendrimer-entrapped gold nanoparticles as a gene vector. , 2020, Journal of materials chemistry. B.

[109]  Challenging paradigms in tumour drug delivery , 2020, Nature Materials.

[110]  D. Zheng,et al.  A vaccine-based nanosystem for initiating innate immunity and improving tumor immunotherapy , 2020, Nature Communications.

[111]  A. Chen,et al.  Targeted tumour theranostics in mice via carbon quantum dots structurally mimicking large amino acids , 2020, Nature Biomedical Engineering.

[112]  M. Jaafari,et al.  Ex vivo-generated dendritic cell-based vaccines in melanoma: the role of nanoparticulate delivery systems. , 2020, Immunotherapy.

[113]  J. M. Lanao,et al.  Targeting of Hepatic Macrophages by Therapeutic Nanoparticles , 2020, Frontiers in Immunology.

[114]  R. Wyatt,et al.  Route of Vaccine Administration Alters Antigen Trafficking but Not Innate or Adaptive Immunity. , 2020, Cell reports.

[115]  Feng Liu,et al.  Quantum dot-pulsed dendritic cell vaccines plus macrophage polarization for amplified cancer immunotherapy. , 2020, Biomaterials.

[116]  Daniel W. Kulp,et al.  In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity , 2020, Advanced science.

[117]  Xing-jie Liang,et al.  Comprehensive understanding of magnetic hyperthermia for improving antitumor therapeutic efficacy , 2020, Theranostics.

[118]  Thanh Loc Nguyen,et al.  Injectable dual-scale mesoporous silica cancer vaccine enabling efficient delivery of antigen/adjuvant-loaded nanoparticles to dendritic cells recruited in local macroporous scaffold. , 2020, Biomaterials.

[119]  Yue Li,et al.  V(D)J recombination, somatic hypermutation and class switch recombination of immunoglobulins: mechanism and regulation , 2020, Immunology.

[120]  R. Jain,et al.  A framework for advancing our understanding of cancer-associated fibroblasts , 2020, Nature Reviews Cancer.

[121]  B. Fadeel,et al.  Silver nanoparticles modulate lipopolysaccharide-triggered Toll-like receptor signaling in immune-competent human cell lines , 2020, Nanoscale advances.

[122]  Qingsheng Wu,et al.  Combined Magnetic Hyperthermia and Immune Therapy for Primary and Metastatic Tumor Treatments. , 2020, ACS nano.

[123]  Peihong Wu,et al.  Bisphosphonate Stabilized Calcium Phosphate Nanoparticles for Effective Delivery of Plasmid DNA to Macrophages. , 2020, ACS applied bio materials.

[124]  C. Drake,et al.  Peptide-TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T cell immunity to tumor antigens , 2019, Nature Biotechnology.

[125]  L. Hofbauer,et al.  Increased pore size of scaffolds improves coating efficiency with sulfated hyaluronan and mineralization capacity of osteoblasts , 2019, Biomaterials research.

[126]  S. Pokhrel,et al.  Model‐Based Nanoengineered Pharmacokinetics of Iron‐Doped Copper Oxide for Nanomedical Applications , 2019, Angewandte Chemie.

[127]  M. Walid Qoronfleh,et al.  Therapeutic efficacy of nanoparticles and routes of administration , 2019, Biomaterials Research.

[128]  James E Dahlman,et al.  Mild Innate Immune Activation Overrides Efficient Nanoparticle‐Mediated RNA Delivery , 2019, Advanced materials.

[129]  Zhuang Liu,et al.  GSH‐Depleted PtCu3 Nanocages for Chemodynamic‐ Enhanced Sonodynamic Cancer Therapy , 2019, Advanced Functional Materials.

[130]  Dong‐Hyun Kim,et al.  Sequential MR Image-Guided Local Immune Checkpoint Blockade Cancer Immunotherapy Using Ferumoxytol Capped Ultralarge Pore Mesoporous Silica Carriers after Standard Chemotherapy. , 2019, Small.

[131]  Adrian Berger,et al.  Anionic nanoparticles enable the oral delivery of proteins by enhancing intestinal permeability , 2019, Nature Biomedical Engineering.

[132]  James E. Crowe,et al.  Mucosal Immunization with a pH-Responsive Nanoparticle Vaccine Induces Protective CD8+ Lung-Resident Memory T Cells. , 2019, ACS nano.

[133]  Daniel G. Anderson,et al.  Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation , 2019, Nature Biotechnology.

[134]  E. Wherry,et al.  Defining ‘T cell exhaustion’ , 2019, Nature Reviews Immunology.

[135]  Cheng Xu,et al.  Positron Emission Tomography-Guided Photodynamic Therapy with Biodegradable Mesoporous Silica Nanoparticles for Personalized Cancer Immunotherapy. , 2019, ACS nano.

[136]  B. Liu,et al.  A tumor microenvironment responsive biodegradable CaCO3/MnO2- based nanoplatform for the enhanced photodynamic therapy and improved PD-L1 immunotherapy , 2019, Theranostics.

[137]  W. Chan,et al.  Nanoparticle size influences antigen retention and presentation in lymph node follicles for humoral immunity. , 2019, Nano letters.

[138]  B. Liu,et al.  Effects of gold nanoprism-assisted human PD-L1 siRNA on both gene down-regulation and photothermal therapy on lung cancer. , 2019, Acta biomaterialia.

[139]  D. F. Barber,et al.  Magnetic Nanoparticles Attached to the NK Cell Surface for Tumor Targeting in Adoptive Transfer Therapies Does Not Affect Cellular Effector Functions , 2019, Front. Immunol..

[140]  M. Penichet,et al.  Blood–brain barrier permeable nano immunoconjugates induce local immune responses for glioma therapy , 2019, Nature Communications.

[141]  Zhenzhong Zhang,et al.  Cancer Cell Membrane-Biomimetic Nanoplatform for Enhanced Sonodynamic Therapy on Breast Cancer via Autophagy Regulation Strategy. , 2019, ACS applied materials & interfaces.

[142]  Conglian Yang,et al.  Intracellularly generated immunological gold nanoparticles for combinatorial photothermal therapy and immunotherapy against tumor. , 2019, Nano letters.

[143]  D. F. Barber,et al.  Magnetic targeting of adoptively transferred tumour-specific nanoparticle-loaded CD8+ T cells does not improve their tumour infiltration in a mouse model of cancer but promotes the retention of these cells in tumour-draining lymph nodes , 2019, Journal of Nanobiotechnology.

[144]  P. Ágoston,et al.  NBTXR3, a first-in-class radioenhancer hafnium oxide nanoparticle, plus radiotherapy versus radiotherapy alone in patients with locally advanced soft-tissue sarcoma (Act.In.Sarc): a multicentre, phase 2-3, randomised, controlled trial. , 2019, The Lancet. Oncology.

[145]  Gorka Orive,et al.  Quantum Dots in Biomedical Applications , 2019, Acta biomaterialia.

[146]  S. Sakaguchi,et al.  Targeting Treg cells in cancer immunotherapy , 2019, European journal of immunology.

[147]  Xing-jie Liang,et al.  Nanoscale Metal-Organic Framework Mediates Radical Therapy to Enhance Cancer Immunotherapy. , 2019, Chem.

[148]  M. Philip,et al.  Heterogeneity and fate choice: T cell exhaustion in cancer and chronic infections. , 2019, Current opinion in immunology.

[149]  Gry Persson,et al.  The Tolerogenic Function of Regulatory T Cells in Pregnancy and Cancer , 2019, Front. Immunol..

[150]  Luodan Yu,et al.  Checkpoint blockade and nanosonosensitizer-augmented noninvasive sonodynamic therapy combination reduces tumour growth and metastases in mice , 2019, Nature Communications.

[151]  E. Wherry,et al.  CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer. , 2019, Annual review of immunology.

[152]  Tingting Wang,et al.  Light-Enhanced O2-Evolving Nanoparticles Boost Photodynamic Therapy To Elicit Antitumor Immunity. , 2019, ACS applied materials & interfaces.

[153]  Quentin Harmer,et al.  Impact of Locally Administered Carboxydextran-Coated Super-Paramagnetic Iron Nanoparticles on Cellular Immune Function. , 2019, Small.

[154]  J. Cyster,et al.  B Cell Responses: Cell Interaction Dynamics and Decisions , 2019, Cell.

[155]  David Baker,et al.  Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus , 2019, Cell.

[156]  Brian Ruffell,et al.  Macrophages as regulators of tumour immunity and immunotherapy , 2019, Nature Reviews Immunology.

[157]  Feng Liu,et al.  Self-Assembled Copper-Amino Acid Nanoparticles for in Situ Glutathione "AND" H2O2 Sequentially Triggered Chemodynamic Therapy. , 2018, Journal of the American Chemical Society.

[158]  Seyed Moein Moghimi,et al.  Immunoglobulin deposition on biomolecule corona determines complement opsonisation efficiency of preclinical and clinical nanoparticles , 2018, Nature Nanotechnology.

[159]  W. Schwindt,et al.  Combined intracavitary thermotherapy with iron oxide nanoparticles and radiotherapy as local treatment modality in recurrent glioblastoma patients , 2018, Journal of Neuro-Oncology.

[160]  Yayi Hou,et al.  Anti-tumor macrophages activated by ferumoxytol combined or surface-functionalized with the TLR3 agonist poly (I : C) promote melanoma regression , 2018, Theranostics.

[161]  Paul J. Hoover,et al.  Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma , 2018, Cell.

[162]  J. Seo,et al.  Cloaking nanoparticles with protein corona shield for targeted drug delivery , 2018, Nature Communications.

[163]  C. Brinker,et al.  Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics , 2018, Nature Communications.

[164]  M. Fortin,et al.  Gold Nanoparticles in Radiotherapy and Recent Progress in Nanobrachytherapy , 2018, Advanced healthcare materials.

[165]  Sven Burgdorf,et al.  Current Concepts of Antigen Cross-Presentation , 2018, Front. Immunol..

[166]  Yifan Ma,et al.  Oxygen-boosted immunogenic photodynamic therapy with gold nanocages@manganese dioxide to inhibit tumor growth and metastases. , 2018, Biomaterials.

[167]  Yongzhong Du,et al.  Sustained release of anti‐PD‐1 peptide for perdurable immunotherapy together with photothermal ablation against primary and distant tumors , 2018, Journal of controlled release : official journal of the Controlled Release Society.

[168]  C. Hsieh,et al.  Combination of fucoidan-based magnetic nanoparticles and immunomodulators enhances tumour-localized immunotherapy , 2018, Nature Nanotechnology.

[169]  Tadaki Suzuki,et al.  Shape-dependent adjuvanticity of nanoparticle-conjugated RNA adjuvants for intranasal inactivated influenza vaccines , 2018, RSC advances.

[170]  Lanxia Liu,et al.  Photothermally Controlled MHC Class I Restricted CD8+ T‐Cell Responses Elicited by Hyaluronic Acid Decorated Gold Nanoparticles as a Vaccine for Cancer Immunotherapy , 2018, Advanced healthcare materials.

[171]  Da-Peng Yang,et al.  Combining Magnetic Resonance Imaging with Photothermal Therapy of CuS@BSA Nanoparticles for Cancer Theranostics , 2018 .

[172]  K. Dawson,et al.  Differential Recognition of Nanoparticle Protein Corona and Modified Low-Density Lipoprotein by Macrophage Receptor with Collagenous Structure. , 2018, ACS nano.

[173]  Yugang Wang,et al.  Exploration of Antigen Induced CaCO3 Nanoparticles for Therapeutic Vaccine. , 2018, Small.

[174]  V. Engelhard,et al.  Immune Cell Infiltration and Tertiary Lymphoid Structures as Determinants of Antitumor Immunity , 2018, The Journal of Immunology.

[175]  I. Amelio,et al.  The hypoxic tumour microenvironment , 2018, Oncogenesis.

[176]  Scott N. Mueller,et al.  Migratory CD11b+ conventional dendritic cells induce T follicular helper cell–dependent antibody responses , 2017, Science Immunology.

[177]  Gordon J. Freeman,et al.  T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity , 2017, Nature Communications.

[178]  Zhuang Liu,et al.  Hollow MnO2 as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses , 2017, Nature Communications.

[179]  Vincent M Rotello,et al.  Effects of engineered nanoparticles on the innate immune system. , 2017, Seminars in immunology.

[180]  Xiaoyuan Chen,et al.  Suppressing Nanoparticle-Mononuclear Phagocyte System Interactions of Two-Dimensional Gold Nanorings for Improved Tumor Accumulation and Photothermal Ablation of Tumors. , 2017, ACS nano.

[181]  R. Ganss,et al.  De novo induction of intratumoral lymphoid structures and vessel normalization enhances immunotherapy in resistant tumors , 2017, Nature Immunology.

[182]  Liping Liu,et al.  Encapsulation of Hydrophilic and Hydrophobic Peptides into Hollow Mesoporous Silica Nanoparticles for Enhancement of Antitumor Immune Response. , 2017, Small.

[183]  M. Blosi,et al.  Lipopolysaccharide Adsorbed to the Bio-Corona of TiO2 Nanoparticles Powerfully Activates Selected Pro-inflammatory Transduction Pathways , 2017, Front. Immunol..

[184]  Laurence Zitvogel,et al.  The immune contexture in cancer prognosis and treatment , 2017, Nature Reviews Clinical Oncology.

[185]  Xiao Han,et al.  Redox-Sensitive Nanoscale Coordination Polymers for Drug Delivery and Cancer Theranostics. , 2017, ACS applied materials & interfaces.

[186]  Jianlin Shi,et al.  Large-pore, silica particles with antibody-like, biorecognition sites for efficient protein separation. , 2017, Journal of materials chemistry. B.

[187]  C. Duvall,et al.  Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol. , 2017, ACS nano.

[188]  Yanhui Qin,et al.  CpG loaded MoS2 nanosheets as multifunctional agents for photothermal enhanced cancer immunotherapy. , 2017, Nanoscale.

[189]  Seyed Moein Moghimi,et al.  Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo. , 2017, Nature nanotechnology.

[190]  Suk-Jo Kang,et al.  Extra-Large Pore Mesoporous Silica Nanoparticles for Directing in Vivo M2 Macrophage Polarization by Delivering IL-4. , 2017, Nano letters.

[191]  Yulei Chang,et al.  Precise Photodynamic Therapy of Cancer via Subcellular Dynamic Tracing of Dual-loaded Upconversion Nanophotosensitizers , 2017, Scientific Reports.

[192]  T. Park,et al.  Diverse Applications of Nanomedicine , 2017, ACS nano.

[193]  M. Collado,et al.  Advances toward More Efficient Targeted Delivery of Nanoparticles in Vivo: Understanding Interactions between Nanoparticles and Cells. , 2017, ACS nano.

[194]  Yi Zhang,et al.  Tumor-associated macrophages: from basic research to clinical application , 2017, Journal of Hematology & Oncology.

[195]  R. Steinhardt,et al.  Surface Coating of Nanoparticles Reduces Background Inflammatory Activity while Increasing Particle Uptake and Delivery. , 2017, ACS biomaterials science & engineering.

[196]  Bengt Fadeel,et al.  Cytotoxic and Proinflammatory Effects of Metal-Based Nanoparticles on THP-1 Monocytes Characterized by Combined Proteomics Approaches. , 2017, Journal of proteome research.

[197]  Xinyang Zhang,et al.  Enhanced Cisplatin Chemotherapy by Iron Oxide Nanocarrier-Mediated Generation of Highly Toxic Reactive Oxygen Species. , 2017, Nano letters.

[198]  Delyan R. Hristov,et al.  Identification of Receptor Binding to the Biomolecular Corona of Nanoparticles. , 2017, ACS nano.

[199]  S. Sakaguchi,et al.  Regulatory T cells in cancer immunotherapy , 2016, Cell Research.

[200]  Laura M Ensign,et al.  Nanoparticles for oral delivery: Design, evaluation and state-of-the-art. , 2016, Journal of controlled release : official journal of the Controlled Release Society.

[201]  Bradley Duncan,et al.  Immunomodulatory effects of coated gold nanoparticles in LPS-stimulated in vitro and in vivo murine model systems. , 2016, Chem.

[202]  David Baker,et al.  Accurate design of megadalton-scale two-component icosahedral protein complexes , 2016, Science.

[203]  F. Quintana,et al.  Tolerogenic nanoparticles inhibit T cell–mediated autoimmunity through SOCS2 , 2016, Science Signaling.

[204]  D. Salah,et al.  Singlet Oxygen Generation by Laser Irradiation of Gold Nanoparticles , 2016, The journal of physical chemistry. C, Nanomaterials and interfaces.

[205]  M. Kundi,et al.  Comparable immune responsiveness but increased reactogenicity after subcutaneous versus intramuscular administration of tick borne encephalitis (TBE) vaccine. , 2016, Vaccine.

[206]  J. DeSimone,et al.  Nanoparticle surface charge impacts distribution, uptake and lymph node trafficking by pulmonary antigen-presenting cells. , 2016, Nanomedicine : nanotechnology, biology, and medicine.

[207]  Lisa M. Coussens,et al.  The Basis of Oncoimmunology , 2016, Cell.

[208]  Ting Liu,et al.  Bioconjugated Manganese Dioxide Nanoparticles Enhance Chemotherapy Response by Priming Tumor-Associated Macrophages toward M1-like Phenotype and Attenuating Tumor Hypoxia. , 2016, ACS nano.

[209]  S. Kaech,et al.  The multifaceted role of CD4+ T cells in CD8+ T cell memory , 2016, Nature Reviews Immunology.

[210]  P. Chu,et al.  Ultrasmall Black Phosphorus Quantum Dots: Synthesis and Use as Photothermal Agents. , 2015, Angewandte Chemie.

[211]  Raimo Hartmann,et al.  Surface Functionalization of Nanoparticles with Polyethylene Glycol: Effects on Protein Adsorption and Cellular Uptake. , 2015, ACS nano.

[212]  D. Drobne,et al.  Nanoparticle interaction with the immune system / Interakcije nanodelcev z imunskim sistemom , 2015, Arhiv za higijenu rada i toksikologiju.

[213]  Elizabeth A. Repasky,et al.  Fever and the thermal regulation of immunity: the immune system feels the heat , 2015, Nature Reviews Immunology.

[214]  Christoffer Åberg,et al.  Mapping protein binding sites on the biomolecular corona of nanoparticles. , 2015, Nature nanotechnology.

[215]  Y. Yao,et al.  Dendrimer-like alpha-d-glucan nanoparticles activate dendritic cells and are effective vaccine adjuvants. , 2015, Journal of controlled release : official journal of the Controlled Release Society.

[216]  C. Mirkin,et al.  Immunomodulatory spherical nucleic acids , 2015, Proceedings of the National Academy of Sciences.

[217]  Scott G. Mitchell,et al.  Dissecting the molecular mechanism of apoptosis during photothermal therapy using gold nanoprisms. , 2015, ACS nano.

[218]  K. Soo,et al.  Nanoparticles in photodynamic therapy. , 2015, Chemical reviews.

[219]  M. Edidin,et al.  Magnetic Field-Induced T Cell Receptor Clustering by Nanoparticles Enhances T Cell Activation and Stimulates Antitumor Activity , 2014, ACS nano.

[220]  B. Bryan,et al.  A genomics approach to identify susceptibilities of breast cancer cells to “fever-range” hyperthermia , 2014, BMC Cancer.

[221]  K. Schäkel,et al.  Low-dose irradiation programs macrophage differentiation to an iNOS⁺/M1 phenotype that orchestrates effective T cell immunotherapy. , 2013, Cancer cell.

[222]  C. Alexander,et al.  Nanoparticle transport in epithelial cells: pathway switching through bioconjugation. , 2013, Small.

[223]  I. Mellman,et al.  Oncology meets immunology: the cancer-immunity cycle. , 2013, Immunity.

[224]  Ick Chan Kwon,et al.  Nanophotosensitizers toward advanced photodynamic therapy of Cancer. , 2013, Cancer letters.

[225]  Takafumi Ninomiya,et al.  Gold nanoparticles as a vaccine platform: influence of size and shape on immunological responses in vitro and in vivo. , 2013, ACS nano.

[226]  I. Merfort,et al.  Oxidative stress and inflammatory response to printer toner particles in human epithelial A549 lung cells. , 2013, Toxicology letters.

[227]  V. Pokharkar,et al.  Quillaja saponaria extract as mucosal adjuvant with chitosan functionalized gold nanoparticles for mucosal vaccine delivery: stability and immunoefficiency studies. , 2013, International journal of pharmaceutics.

[228]  Patrick Couvreur,et al.  Magnetic nanoparticles: design and characterization, toxicity and biocompatibility, pharmaceutical and biomedical applications. , 2012, Chemical reviews.

[229]  I. Mellman,et al.  Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells. , 2012, Blood.

[230]  R. Dummer,et al.  Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8+ T-cell responses in melanoma patients , 2012, European journal of immunology.

[231]  O. Joffre,et al.  Cross-presentation by dendritic cells , 2012, Nature Reviews Immunology.

[232]  E. Wherry,et al.  Progressive Loss of Memory T Cell Potential and Commitment to Exhaustion during Chronic Viral Infection , 2012, Journal of Virology.

[233]  Dan Peer,et al.  Nanoparticle hydrophobicity dictates immune response. , 2012, Journal of the American Chemical Society.

[234]  P. Gao,et al.  Synthesis of a novel kind of carbon nanoparticle with large mesopores and macropores and its application as an oral vaccine adjuvant. , 2011, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[235]  Young Keun Kim,et al.  A multifunctional core-shell nanoparticle for dendritic cell-based cancer immunotherapy. , 2011, Nature nanotechnology.

[236]  Davoud Ahmadvand,et al.  Material properties in complement activation. , 2011, Advanced drug delivery reviews.

[237]  Bengt Fadeel,et al.  Direct effects of carbon nanotubes on dendritic cells induce immune suppression upon pulmonary exposure. , 2011, ACS nano.

[238]  P. Kolattukudy,et al.  Cerium Oxide Nanoparticles Inhibits Oxidative Stress and Nuclear Factor-κB Activation in H9c2 Cardiomyocytes Exposed to Cigarette Smoke Extract , 2011, Journal of Pharmacology and Experimental Therapeutics.

[239]  H. Dai,et al.  Ultrasmall reduced graphene oxide with high near-infrared absorbance for photothermal therapy. , 2011, Journal of the American Chemical Society.

[240]  L. Zitvogel,et al.  Restoration of the immunogenicity of cisplatin-induced cancer cell death by endoplasmic reticulum stress , 2011, Oncogene.

[241]  R. Madan,et al.  Sipuleucel-T: harbinger of a new age of therapeutics for prostate cancer , 2011, Expert review of vaccines.

[242]  D. Roopenian,et al.  Efficient Mucosal Delivery of Vaccine Using the FcRn-Mediated IgG Transfer Pathway , 2011, Nature biotechnology.

[243]  Martin F. Bachmann,et al.  Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns , 2010, Nature Reviews Immunology.

[244]  Byung-Hoon Lee,et al.  Genomics-based screening of differentially expressed genes in the brains of mice exposed to silver nanoparticles via inhalation , 2010 .

[245]  Marina A Dobrovolskaia,et al.  Nanoparticles and the immune system. , 2010, Endocrinology.

[246]  Z. Marković,et al.  Opposite effects of nanocrystalline fullerene (C(60)) on tumour cell growth in vitro and in vivo and a possible role of immunosupression in the cancer-promoting activity of C(60). , 2009, Biomaterials.

[247]  S W Burchiel,et al.  Mechanisms for how inhaled multiwalled carbon nanotubes suppress systemic immune function in mice. , 2009, Nature nanotechnology.

[248]  T. Lebien,et al.  B lymphocytes: how they develop and function. , 2008, Blood.

[249]  Sai T Reddy,et al.  Exploiting lymphatic transport and complement activation in nanoparticle vaccines , 2007, Nature Biotechnology.

[250]  Oliver T. Bruns,et al.  Size and surface effects on the MRI relaxivity of manganese ferrite nanoparticle contrast agents. , 2007, Nano letters.

[251]  Jan Holmgren,et al.  Mucosal immunity and vaccines , 2005, Nature Medicine.

[252]  S. Rosenberg,et al.  Cancer immunotherapy: moving beyond current vaccines , 2004, Nature Medicine.

[253]  E. Wherry,et al.  Vaccines: Effector and memory T-cell differentiation: implications for vaccine development , 2002, Nature Reviews Immunology.

[254]  S. Stolik,et al.  Measurement of the penetration depths of red and near infrared light in human "ex vivo" tissues. , 2000, Journal of photochemistry and photobiology. B, Biology.

[255]  H. Maeda,et al.  A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. , 1986, Cancer research.