Regulation of asymmetric cell division and polarity by Scribble is not required for humoral immunity

[1]  Barbara Hausmann,et al.  T cell affinity regulates asymmetric division, effector cell differentiation, and tissue pathology. , 2012, Immunity.

[2]  R. Huganir,et al.  Characterization of In Vivo Dlg1 Deletion on T Cell Development and Function , 2012, PloS one.

[3]  Andrew Filby,et al.  Reporting imaging flow cytometry data for publication: Why mask the detail? , 2012, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

[4]  L. Aravind,et al.  The Scaffolding Protein Synapse-Associated Protein 97 Is Required for Enhanced Signaling Through Isotype-Switched IgG Memory B Cell Receptors , 2012, Science Signaling.

[5]  D. Tarlinton,et al.  Determining germinal centre B cell fate. , 2012, Trends in immunology.

[6]  J. Trapani,et al.  This information is current as Granzyme B Activated Mouse B Cells Lack Expression of Hawkins and , 2012 .

[7]  Facundo D. Batista,et al.  Asymmetric Segregation of Polarized Antigen on B Cell Division Shapes Presentation Capacity , 2012, Science.

[8]  Jhagvaral Hasbold,et al.  Activation-Induced B Cell Fates Are Selected by Intracellular Stochastic Competition , 2012, Science.

[9]  Michael P. Cancro,et al.  Asymmetric B Cell Division in the Germinal Center Reaction , 2012, Science.

[10]  D. Tuveson,et al.  SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia. , 2011, The Journal of clinical investigation.

[11]  Huw Summers,et al.  An imaging flow cytometric method for measuring cell division history and molecular symmetry during mitosis , 2011, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

[12]  John T. Chang,et al.  Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division. , 2011, Immunity.

[13]  T. Pawson,et al.  Immature T-cell clustering and efficient differentiation require the polarity protein Scribble , 2010, Proceedings of the National Academy of Sciences.

[14]  Y. Taketani,et al.  The cell polarity regulator hScrib controls ERK activation through a KIM site-dependent interaction , 2010, Oncogene.

[15]  John T. Chang,et al.  Asymmetric Cell Division of T Cells upon Antigen Presentation Uses Multiple Conserved Mechanisms , 2010, The Journal of Immunology.

[16]  S. Nutt,et al.  Blimp-1 transcription factor is required for the differentiation of effector CD8(+) T cells and memory responses. , 2009, Immunity.

[17]  K. Prehoda,et al.  aPKC Phosphorylates Miranda to Polarize Fate Determinants during Neuroblast Asymmetric Cell Division , 2009, Current Biology.

[18]  Daniel Day,et al.  A method for prolonged imaging of motile lymphocytes , 2009, Immunology and cell biology.

[19]  H. Richardson,et al.  Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module , 2008, Oncogene.

[20]  H. Richardson,et al.  Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling , 2008, Oncogene.

[21]  Takashi Nishimura,et al.  Linking Cell Cycle to Asymmetric Division: Aurora-A Phosphorylates the Par Complex to Regulate Numb Localization , 2008, Cell.

[22]  E. D. De Robertis,et al.  Asymmetric mitosis: Unequal segregation of proteins destined for degradation , 2008, Proceedings of the National Academy of Sciences.

[23]  John F Markham,et al.  Measuring lymphocyte proliferation, survival and differentiation using CFSE time-series data , 2007, Nature Protocols.

[24]  Nikhil S. Joshi,et al.  Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. , 2007, Immunity.

[25]  John T. Chang,et al.  Asymmetric T Lymphocyte Division in the Initiation of Adaptive Immune Responses , 2007, Science.

[26]  P. Hodgkin,et al.  A model of immune regulation as a consequence of randomized lymphocyte division and death times , 2007, Proceedings of the National Academy of Sciences.

[27]  T. Phan,et al.  High affinity germinal center B cells are actively selected into the plasma cell compartment , 2006, The Journal of experimental medicine.

[28]  Christopher C. Goodnow,et al.  ERK Signaling Is a Molecular Switch Integrating Opposing Inputs from B Cell Receptor and T Cell Cytokines to Control TLR4-Driven Plasma Cell Differentiation1 , 2006, The Journal of Immunology.

[29]  T. Phan,et al.  Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation , 2006, The Journal of experimental medicine.

[30]  K. Mechtler,et al.  Asymmetric Segregation of the Tumor Suppressor Brat Regulates Self-Renewal in Drosophila Neural Stem Cells , 2006, Cell.

[31]  Kristin J. Robinson,et al.  Lgl, Pins and aPKC regulate neuroblast self-renewal versus differentiation , 2006, Nature.

[32]  E. Caussinus,et al.  Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster , 2005, Nature Genetics.

[33]  M. Smyth,et al.  A network of PDZ-containing proteins regulates T cell polarity and morphology during migration and immunological synapse formation. , 2005, Immunity.

[34]  S. Tapscott,et al.  Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice. , 2004, Genes & development.

[35]  S. Tangye,et al.  Evidence from the generation of immunoglobulin G–secreting cells that stochastic mechanisms regulate lymphocyte differentiation , 2004, Nature Immunology.

[36]  J. Trapani,et al.  hScrib is a functional homologue of the Drosophila tumour suppressor Scribble , 2003, Oncogene.

[37]  K. Mechtler,et al.  The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl , 2003, Nature.

[38]  C. Doe,et al.  Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry , 2003, Nature Cell Biology.

[39]  P. Doherty,et al.  Diversity of Epitope and Cytokine Profiles for Primary and Secondary Influenza A Virus-Specific CD8+ T Cell Responses1 , 2001, The Journal of Immunology.

[40]  A. Bernstein,et al.  Craniofacial Dysmorphogenesis Including Cleft Palate in Mice with an Insertional Mutation in the discs large Gene , 2001, Molecular and Cellular Biology.

[41]  J. Altman,et al.  A Previously Unrecognized H-2Db-Restricted Peptide Prominent in the Primary Influenza A Virus-Specific CD8+T-Cell Response Is Much Less Apparent following Secondary Challenge , 2000, Journal of Virology.

[42]  M. Neuberger,et al.  B cells extract and present immobilized antigen: implications for affinity discrimination , 2000, The EMBO journal.

[43]  J. Altman,et al.  Virus-specific CD8+ T cells in primary and secondary influenza pneumonia. , 1998, Immunity.

[44]  Kenneth G. C. Smith,et al.  The extent of affinity maturation differs between the memory and antibody‐forming cell compartments in the primary immune response , 1997, The EMBO journal.

[45]  J. Davey,et al.  Cytotoxic T cells recognize fragments of the influenza nucleoprotein , 1985, Cell.

[46]  J Steinkamp,et al.  Cell heterogeneity during the cell cycle , 1982, Journal of cellular physiology.