Essential function in vivo for Dicer-2 in host defense against RNA viruses in drosophila

[1]  J. Imler,et al.  Toll-like receptors and innate antiviral immunity. , 2006, Tissue antigens.

[2]  A. James,et al.  Engineering RNA interference-based resistance to dengue virus type 2 in genetically modified Aedes aegypti. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[3]  Shizuo Akira,et al.  Innate immune recognition of viral infection , 2006, Nature Immunology.

[4]  J. Lieberman,et al.  An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection , 2006, Nature.

[5]  S. Whelan,et al.  An antiviral role for the RNA interference machinery in Caenorhabditis elegans. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[6]  June Hyung Lee,et al.  Dual modes of RNA-silencing suppression by Flock House virus protein B2 , 2005, Nature Structural &Molecular Biology.

[7]  David P. Bartel,et al.  Partially Redundant Functions of Arabidopsis DICER-like Enzymes and a Role for DCL4 in Producing trans-Acting siRNAs , 2005, Current Biology.

[8]  N. Zhong,et al.  Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque , 2005, Nature Medicine.

[9]  Khaled Machaca,et al.  RNA interference is an antiviral defence mechanism in Caenorhabditis elegans , 2005, Nature.

[10]  Morris F. Maduro,et al.  Animal virus replication and RNAi-mediated antiviral silencing in Caenorhabditis elegans , 2005, Nature.

[11]  J. Hoffmann,et al.  The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila , 2005, Nature Immunology.

[12]  Olivier Voinnet,et al.  Induction and suppression of RNA silencing: insights from viral infections , 2005, Nature Reviews Genetics.

[13]  N. Perrimon,et al.  Genome-wide RNAi screen reveals a specific sensitivity of IRES-containing RNA viruses to host translation inhibition. , 2005, Genes & development.

[14]  S. Barik,et al.  Inhibition of respiratory viruses by nasally administered siRNA , 2005, Nature Medicine.

[15]  Hong Yang,et al.  Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene , 2005, Nature Medicine.

[16]  B. Foy,et al.  RNA interference acts as a natural antiviral response to O'nyong-nyong virus (Alphavirus; Togaviridae) infection of Anopheles gambiae. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[17]  T. Tuschl,et al.  Mechanisms of gene silencing by double-stranded RNA , 2004, Nature.

[18]  Akira Ishizuka,et al.  Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways. , 2004, Genes & development.

[19]  Qing Ge,et al.  Inhibition of influenza virus production in virus-infected mice by RNA interference. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[20]  T. Tumpey,et al.  Protection against lethal influenza virus challenge by RNA interference in vivo. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[21]  E. Sontheimer,et al.  Distinct Roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA Silencing Pathways , 2004, Cell.

[22]  Norbert Perrimon,et al.  The roles of JAK/STAT signaling in Drosophila immune responses , 2004, Immunological reviews.

[23]  K. Anderson,et al.  Drosophila: the genetics of innate immune recognition and response. , 2004, Annual review of immunology.

[24]  Adam M. Gustafson,et al.  Genetic and Functional Diversification of Small RNA Pathways in Plants , 2004, PLoS biology.

[25]  Shou-Wei Ding,et al.  Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[26]  O. Terenius,et al.  Parasite‐specific immune response in adult Drosophila melanogaster: a genomic study , 2004, EMBO reports.

[27]  D. Bartel.  MicroRNAs Genomics, Biogenesis, Mechanism, and Function , 2004, Cell.

[28]  N. Perrimon,et al.  Entry is a rate-limiting step for viral infection in a Drosophila melanogaster model of pathogenesis , 2004, Nature Immunology.

[29]  J. Hoffmann,et al.  The immune response of Drosophila , 2003, Nature.

[30]  S. Elledge,et al.  Dicer is essential for mouse development , 2003, Nature Genetics.

[31]  D. Zachary,et al.  Pherokine-2 and -3. , 2003, European journal of biochemistry.

[32]  Christophe Antoniewski,et al.  Absence of transitive and systemic pathways allows cell-specific and isoform-specific RNAi in Drosophila. , 2003, RNA.

[33]  D. Hultmark.  Drosophila immunity: paths and patterns. , 2003, Current opinion in immunology.

[34]  B. Beutler,et al.  Innate immune sensing and its roots: the story of endotoxin , 2003, Nature Reviews Immunology.

[35]  A. Schneemann,et al.  Analysis of RNA packaging in wild-type and mosaic protein capsids of flock house virus using recombinant baculovirus vectors. , 2003, Virology.

[36]  S. Ding,et al.  Induction and Suppression of RNA Silencing by an Animal Virus , 2002, Science.

[37]  Charles A. Janeway,et al.  Decoding the Patterns of Self and Nonself by the Innate Immune System , 2002, Science.

[38]  L. A. Ball,et al.  Characterization and template properties of RNA dimers generated during flock house virus RNA replication. , 2001, Virology.

[39]  D. Zachary,et al.  Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis. , 2001, Developmental cell.

[40]  Ming-Bo Wang,et al.  Gene silencing as an adaptive defence against viruses , 2001, Nature.

[41]  L K Miller,et al.  An exegesis of IAPs: salvation and surprises from BIR motifs. , 1999, Trends in cell biology.

[42]  F C Kafatos,et al.  Phylogenetic perspectives in innate immunity. , 1999, Science.

[43]  D. Baulcombe,et al.  Systemic Spread of Sequence-Specific Transgene RNA Degradation in Plants Is Initiated by Localized Introduction of Ectopic Promoterless DNA , 1998, Cell.

[44]  John E. Johnson,et al.  The structure and function of nodavirus particles: a paradigm for understanding chemical biology. , 1998, Advances in virus research.

[45]  H. Vaucheret,et al.  Systemic acquired silencing: transgene‐specific post‐transcriptional silencing is transmitted by grafting from silenced stocks to non‐silenced scions , 1997, The EMBO journal.

[46]  D. Baulcombe,et al.  A similarity between viral defense and gene silencing in plants. , 1997, Science.

[47]  L. A. Ball,et al.  Requirements for the self-directed replication of flock house virus RNA 1 , 1995, Journal of virology.

[48]  C. Rieder,et al.  Greatwall kinase , 2004, The Journal of cell biology.

[49]  N. Perrimon,et al.  Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. , 1993, Development.