Leukocyte and endothelial cell adhesion molecules as targets for therapeutic interventions in inflammatory disease.
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[1] K. Ley,et al. P-selectin Glycoprotein Ligand-1 Mediates L-Selectin–dependent Leukocyte Rolling in Venules , 2003, The Journal of experimental medicine.
[2] W. Hagmann,et al. VLA‐4 antagonists: Potent inhibitors of lymphocyte migration , 2003, Medicinal research reviews.
[3] P. Elliott,et al. Proteasome inhibition: a new anti-inflammatory strategy , 2003, Journal of Molecular Medicine.
[4] S. Bodary,et al. Adhesion molecules as therapeutic targets for autoimmune diseases and transplant rejection , 2003, Expert opinion on biological therapy.
[5] M. Schön,et al. Interfering with leukocyte rolling--a promising therapeutic approach in inflammatory skin disorders? , 2003, Trends in pharmacological sciences.
[6] Subrata Ghosh,et al. Natalizumab for active Crohn's disease. , 2003, The New England journal of medicine.
[7] David H. Miller,et al. A controlled trial of natalizumab for relapsing multiple sclerosis. , 2003, The New England journal of medicine.
[8] G. Wolff,et al. Development of Synthetic Pan-Selectin Antagonists: A New Treatment Strategy for Chronic Inflammation in Asthma , 2003, Pathobiology.
[9] J. Mocco,et al. HuEP5C7 as a Humanized Monoclonal Anti-E/P-Selectin Neurovascular Protective Strategy in a Blinded Placebo-Controlled Trial of Nonhuman Primate Stroke , 2002, Circulation research.
[10] N. Kaila,et al. Design and synthesis of sialyl Lewisx mimics as E‐ and P‐selectin inhibitors , 2002, Medicinal research reviews.
[11] R. Gibbons,et al. The effect of blockade of the CD11/CD18 integrin receptor on infarct size in patients with acute myocardial infarction treated with direct angioplasty: the results of the HALT-MI study. , 2002, Journal of the American College of Cardiology.
[12] R. Horuk,et al. Chemokines, chemokine receptors and small-molecule antagonists: recent developments. , 2002, Trends in pharmacological sciences.
[13] G. Weitz-Schmidt,et al. Statins as anti-inflammatory agents. , 2002, Trends in pharmacological sciences.
[14] N. Hogg,et al. Mechanisms contributing to the activity of integrins on leukocytes , 2002, Immunological reviews.
[15] Michael Loran Dustin,et al. The immunological synapse: integrins take the stage , 2002, Immunological reviews.
[16] J. Lowe. Glycosylation in the control of selectin counter‐receptor structure and function , 2002, Immunological reviews.
[17] Junichi Takagi,et al. Integrin activation and structural rearrangement , 2002, Immunological reviews.
[18] P. Rutgeerts,et al. Antiadhesion molecule therapy in inflammatory bowel disease. , 2002, Inflammatory bowel diseases.
[19] D. Sutherlin,et al. Selective α4β7 Integrin Antagonists and Their Potential as Antiinflammatory Agents , 2002 .
[20] M. Perretti,et al. Regulation of Leukocyte‐Endothelial Interactions by Glucocorticoids , 2002, Annals of the New York Academy of Sciences.
[21] David Y Jackson,et al. Alpha 4 integrin antagonists. , 2002, Current pharmaceutical design.
[22] A. Milici,et al. Pulmonary Eosinophilia in a Murine Model of Allergic Inflammation Is Attenuated by Small Molecule α4β1 Antagonists , 2002 .
[23] J. Harlan,et al. Leukocyte-endothelial interactions: Clinical trials of anti-adhesion therapy , 2002, Critical care medicine.
[24] C. Griffiths,et al. Anti‐E‐selectin is ineffective in the treatment of psoriasis: a randomized trial , 2002, The British journal of dermatology.
[25] W. Muller,et al. Leukocyte-Endothelial Cell Interactions in the Inflammatory Response , 2002, Laboratory Investigation.
[26] H. Gollnick,et al. Efomycine M, a new specific inhibitor of selectin, impairs leukocyte adhesion and alleviates cutaneous inflammation , 2002, Nature Medicine.
[27] R. Cummings,et al. P-selectin glycoprotein ligand-1-deficient mice have impaired leukocyte tethering to E-selectin under flow. , 2002, The Journal of clinical investigation.
[28] Helena Yusuf-Makagiansar,et al. Inhibition of LFA‐1/ICAM‐1 and VLA‐4/VCAM‐1 as a therapeutic approach to inflammation and autoimmune diseases , 2002, Medicinal research reviews.
[29] David A. Cheresh,et al. Role of integrins in cell invasion and migration , 2002, Nature Reviews Cancer.
[30] M. Díaz-Ricart,et al. Treatment of acute myocardial infarction thrombolytic P-selectin inhibitor , 2002 .
[31] G. Zimmerman,et al. Leukocyte adhesion deficiency syndromes: adhesion and tethering defects involving beta 2 integrins and selectin ligands. , 2002, Current opinion in hematology.
[32] R. Gibbons,et al. Double-Blind, Randomized Trial of an Anti-CD18 Antibody in Conjunction With Recombinant Tissue Plasminogen Activator for Acute Myocardial Infarction: Limitation of Myocardial Infarction Following Thrombolysis in Acute Myocardial Infarction (LIMIT AMI) Study , 2001, Circulation.
[33] Enlimomab Acute Stroke Trial Investigators. Use of anti-ICAM-1 therapy in ischemic stroke , 2001, Neurology.
[34] L. Kifle,et al. Selective inhibition of ICAM-1 and E-selectin expression in human endothelial cells. 2. Aryl modifications of 4-(aryloxy)thieno[2,3-c]pyridines with fine-tuning at C-2 carbamides. , 2001, Journal of medicinal chemistry.
[35] E B Reilly,et al. Discovery of potent antagonists of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction. 3. Amide (C-ring) structure-activity relationship and improvement of overall properties of arylthio cinnamides. , 2001, Journal of medicinal chemistry.
[36] L. Lindbom,et al. Importance of Primary Capture and L-Selectin–Dependent Secondary Capture in Leukocyte Accumulation in Inflammation and Atherosclerosis in Vivo , 2001, The Journal of experimental medicine.
[37] Romano Sj,et al. Targeting selectins for the treatment of respiratory diseases. , 2001 .
[38] J. Marth,et al. Severe impairment of leukocyte rolling in venules of core 2 glucosaminyltransferase-deficient mice. , 2001, Blood.
[39] D. Slee,et al. Development of potent non-carbohydrate imidazole-based small molecule selectin inhibitors with antiinflammatory activity. , 2001, Journal of medicinal chemistry.
[40] F. Sánchez‐Madrid,et al. Drugs, inflammation and cell adhesion receptors , 2001, Expert opinion on pharmacotherapy.
[41] G. Liu. Inhibitors of LFA-1/ICAM-1 interaction: From monoclonal antibodies to small molecules , 2001 .
[42] K. Ley,et al. Functions of selectins. , 2001, Results and problems in cell differentiation.
[43] K. Ley. Pathways and bottlenecks in the web of inflammatory adhesion molecules and chemoattractants , 2001, Immunologic research.
[44] R. Dixon,et al. Inhibition of coronary thrombosis and local inflammation by a noncarbohydrate selectin inhibitor. , 2000, American journal of physiology. Heart and circulatory physiology.
[45] C. Mackay,et al. T-cell function and migration. Two sides of the same coin. , 2000, The New England journal of medicine.
[46] P. Rieu,et al. Neutrophils: Molecules, Functions and Pathophysiological Aspects , 2000, Laboratory Investigation.
[47] D. Lefer. Pharmacology of selectin inhibitors in ischemia/reperfusion states. , 2000, Annual review of pharmacology and toxicology.
[48] B. Furie,et al. Targeted Gene Disruption Demonstrates That P-Selectin Glycoprotein Ligand 1 (Psgl-1) Is Required for P-Selectin–Mediated but Not E-Selectin–Mediated Neutrophil Rolling and Migration , 1999, The Journal of experimental medicine.
[49] P. Reilly,et al. Cutting edge: a small molecule antagonist of LFA-1-mediated cell adhesion. , 1999, Journal of immunology.
[50] C. Lowell,et al. Integrin signalling in neutrophils and macrophages. , 1999, Cellular signalling.
[51] R. B. Pepinsky,et al. Selective, tight-binding inhibitors of integrin α4β1 that inhibit allergic airway responses , 1999 .
[52] D. Vestweber,et al. Mechanisms that regulate the function of the selectins and their ligands. , 1999, Physiological reviews.
[53] T. Richards,et al. Phase I study of a humanized anti‐CD11/CD18 monoclonal antibody in multiple sclerosis , 1998, Clinical pharmacology and therapeutics.
[54] R. Dixon,et al. Novel synthetic inhibitors of selectin-mediated cell adhesion: synthesis of 1,6-bis[3-(3-carboxymethylphenyl)-4-(2-alpha-D- mannopyranosyloxy)phenyl]hexane (TBC1269). , 1998, Journal of medicinal chemistry.
[55] E. Butcher,et al. Molecular Mechanisms of Lymphocyte Homing to Peripheral Lymph Nodes , 1998, The Journal of experimental medicine.
[56] E. Berg,et al. α4 integrins mediate lymphocyte attachment and rolling under physiologic flow , 1995, Cell.
[57] T. Carlos,et al. Leukocyte-endothelial adhesion molecules. , 1994, Blood.
[58] John I. Gallin,et al. Inflammation: Basic Principles and Clinical Correlates , 1992 .
[59] S. Watson,et al. The three members of the selectin receptor family recognize a common carbohydrate epitope, the sialyl Lewis(x) oligosaccharide , 1992, The Journal of cell biology.